DiseaseINFOPACK: Enterovirus-71
VacZine Analytics
August 1, 2009 64 Pages - SKU: VZAN2467543
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Enterovirus 71 (EV-71) is a common etiologic agent of hand-foot and mouth (HFM) disease which is mainly a disease of children <10 yrs. Although prodrome symptoms of HFM are self resolving, EV-71 can also cause severe neurologic disease including encephalitis, meningitis, and polio-like paralysis. In particular EV-71 has caused epidemics in the Western pacific region such as Taiwan (1998), Singapore (2000) and China (2007) In the Taiwan epidemic 32% of cases experienced complications of which 6.8% involved fatal pulmonary edema. In July 2008, the Chinese CDC reported that 176,000 cases occurred in a single month (May).
Because of its potential to cause mortality and severe morbidity in children, and regional significance, EV-71 appears an attractive target for a vaccine-based preventative approach. This expert DiseaseINFOPACK report gives a comprehensive situation overview of current EV-71 disease dynamics and regional epidemiology. EV-71 is under consideration by a number of commercial manufacturers.
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- Executive summary
- The pathogen
- Clinical features: mild EV-71 infection
- Clinical features: severe EV-71 infection
- Host response
- Risk groups
- Transmission
- Treatment
- Prevention and control
- Diagnosis
- Surveillance
- Epidemiology: Overview
- Epidemiology: China
- Epidemiology: Taiwan
- Epidemiology: Singapore
- Epidemiology: Thailand
- Epidemiology: Malaysia
- Epidemiology: Vietnam
- Epidemiology: South Korea
- Epidemiology: Japan
- Epidemiology: Australia
- Epidemiology: US
- Epidemiology: Europe
- Epidemiology: Other
- Mortality
- Morbidity
- Vaccine Pipeline
- Opportunity for new treatments
- Appendix I - Bibliography
- Appendix II - About VacZine Analytics
- Disclaimer
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