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| Chikungunya virus (CHIK) is an arthropod-borne RNA virus (arbovirus) which causes an acute illness including fever, skin rash, and incapacitating arthralgia. In some cases the virus can cause recurrent disease, neurological complications and severe neonatal disease (encephalopathy). Although CHIK is endemic in Africa/Southeast Asia, recent outbreaks during 2004-2007 have reached new geographical areas where cases are now reported in Europe, Hong-Kong, Canada, Taiwan and the USA. In some cases, these are directly associated with the return of infected tourists from India and islands of the Indian Ocean. Moreover, in 2007, the first CHIK outbreak was recorded in a temperate region of North Eastern of Italy with more than 200 cases .
This expert report provides an up-to-date comprehensive review of current literature pertaining to Chikungunya virus including its epidemiology (outbreaks), surveillance and dynamics. The report seeks to explore whether the virus is a real emerging threat due to drivers such as global warming, changing distribution of Chikungunya virus vectors and population immunity. Lastly, past and current candidate vaccine-based approaches to Chikungunya virus are discussed. Please note: this is delivered as a Zip file. |
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