Disease INFOPACK: Chlamydia trachomatis
VacZine Analytics
May 1, 2008 50 Pages - SKU: VZAN1828262
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| Chlamydia trachomatis is an intracellular Gram-negative bacterium and a leading cause worldwide of sexually-transmitted disease and preventable blindness. The pathogen is a major cause of serious reproductive complications in the female with outcomes such as pelvic inflammatory disease (PID) and ectopic pregnancies. Although diagnosed infections with Chlamydia trachomatis are curable with antibiotic therapy the vast majority infections are “silent” and unrecognized. This is of concern due to continued transmission especially among individuals below 30 years of age. This DiseaseINFOPACK report is an expert review of the current literature regarding Chlamydia trachomatis. Particular emphasis has been placed on proprietary calculations of global incidence and prevalence based on available literature and “in-house” methodology. Key issues and challenges with regard to developing an effective prophylatic vaccine are also noted.
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- Executive summary (1)
- Executive summary (2)
- Authors Note
- The Pathogen
- Serovars
- Clinical Features
- Pathogenesis
- Host Response
- Transmission
- Risk Factors
- Prevention and Control
- Diagnosis
- Treatment
- Morbidity
- Morbidity (cont.)
- Pelvic Inflammatory Disease
- Pelvic Inflammatory Disease - Incidence
- Natural History of Infection
- Global Incidence
- US Incidence
- UK Incidence
- Reasons for Continuing Increase
- Cases by Age and Sex (US)
- Cases by Age and Sex (UK)
- Reasons for Gender Difference
- US Prevalence
- US Prevalence (sex, age group - 2007)
- UK Prevalence (sex, age group - 2007)
- Prevalence: Selected Countries
- Gardasil Registration Studies
- Regional Prevalence
- Calculation of Regional Prevalence
- Comments on Data Accuracy
- Key Issues and Challenges
- Opportunities for New Treatments
- Appendix I - Back-up
- Appendix II - Bibliography
- Appendix III - About VacZine Analytics
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