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Microarray Markets

TriMark Publications
September 1, 2008
132 Pages - SKU: TRI2207060

Attention: There is an updated edition available for this report.

Abstract Table of Contents Related Reports

A microarray is an arrangement of miniaturized test sites or “spots” on a surface. Each spot is usually no more than 250 micrometers in diameter and contains biological molecules—usually DNA or protein—which act as probes for a test sample applied to the array. The surface may be a glass slide, a plastic plate with wells or a polymer bead. The microarray format allows many tests or experiments to be performed simultaneously, in parallel, leading to the generation of huge amounts of biological information for the application of only a tiny amount of sample. Microarrays are often also known as “biochips”. The purpose of this TriMark Publications report is to describe the specific segment of the microarray market aimed at analysis of proteins and DNA. Protein microarray applications include: 1) expression profiling; 2) serum-based diagnostics; 3) protein-protein binding assays; 4 drug-target binding; and 5) receptor epitope binding. It examines the market for DNA and protein array testing equipment and supplies using screening reagents and instruments for analysis of individual components in blood, serum or plasma. It defines the dollar volume of sales, both worldwide and in the U.S., and analyzes the factors that influence the size and the growth of the market segments. Also examined are the subsections of each market segment, including the research labs, hospital labs, and commercial laboratories. Additionally, the numbers of institutions using this type of testing and the factors that influence purchases are discussed. The report surveys almost all of the companies known to be marketing, manufacturing or developing instruments and reagents for the protein array market in the U.S. Each company is discussed in depth with a section on its history, product line, business and marketing analysis, and a subjective commentary of the company’s market position.

1. Overview: 1.1 Statement of Report; 1.2 About This Report; 1.3 Scope of the Report; 1.4 Objectives; 1.5 Methodology; 1.6 Executive Summary
2. Overview of Microarrays: 2.1 History of Microarrays; 2.2 Genomics and Proteomics; 2.3 General Theory of Microarrays; 2.4 DNA Microarrays; 2.5 Protein Microarrays; 2.6 Tissue Microarrays
3. DNA Microarrays: 3.1 Advantages and Drivers; 3.2 Limitations and Barriers to Commercialization; 3.3 DNA Microarray Technology Platforms; 3.4 Key Attributes of DNA Microarray Software; 3.5 Applications; 3.6 Future Directions for DNA Microarray Technology; 3.7 Competitive Landscape for DNA Microarrays
4. Protein Microarrays: 4.1 Critical Factors for Microarray Content; 4.2 Key Findings on Use of Microarrays; 4.3 Advantages and Drivers; 4.4 Limitations and Barriers to Commercialization; 4.5 Key Experimental Parameters of Protein Microarray Technology for Current and Future Users; 4.6 Reasons Why Researchers Utilize Protein Microarrays; 4.7 Factors for Adoption of Protein Microarrays Technology; 4.8 Top Suppliers of Protein Microarray Slides and Products; 4.9 Factors that Influence Sale Decisions; 4.10 Future Innovations in Protein Microarray Technology
5. Current DNA Microarrays: 5.1 Key Players; 5.3 Future Innovations in DNA Microarray Technology
6. Current Protein Microarrays: 6.1 Protein Profiling Microarrays—Antibody Arrays; 6.2 Protein Profiling Microarrays—Reverse Phase Microarrays; 6.3 Multiplex Sandwich Microarrays—Planar; 6.4 Multiplex Sandwich Immunoassays—Bead Based; 6.5 Microarrays for Protein Function Studies; 6.6 High Growth Applications
7. Technology: 7.1 Production of Microarrays; 7.2 2-D Versus 3-D Technology; 7.3 Substrates and Surface Chemistries; 7.4 Detection Methods; 7.5 Instruments; 7.6 Data Management and Informatics in Gene Expression
8. Applications: 8.1 DNA Microarrays in Gene Expression; 8.2 DNA Microarrays in SNP Analysis; 8.3 DNA Microarrays in Cancer; 8.4 Protein Expression; 8.5 Target /Biomarker Discovery; 8.6 Drug Discovery and Development (Gene and Protein Microarrays); 8.7 Clinical Diagnostics (Gene and Protein Microarrays); 8.8 RNA Microarrays; 8.9 Oligo Microarrays; 8.10 Yeast Microarrays; 8.11 Antibody Arrays; 8.12 Arrays for Toxicogenomics
9. The Commercial Opportunity for Microarrays: 9.1 Market Drivers for Microarrays; 9.2 Market Restraints for Microarrays; 9.3 Key Players; 9.4 Market Size, Strategic Trends and Competitive Landscape for Protein Arrays; 9.5 Marketing and Distribution; 9.6 Protein Arrays Market Analysis; 9.7 Genes Associated with Major Diseases; 9.8 Software and Data Analysis
10. Company Profiles: 10.1 Manufacturers
LIST OF FIGURES: Figure 6.1: Cytokines and Growth Factors: Sources of Microarrays for Cytokine Research; Figure 8.1: Microbial Genotyping: Applications for DNA Microarrays; Figure 8.2: Source of Variation in Microarray Data; Figure 8.3: Toxicogenomics: DNA Microarrays
LIST OF TABLES: Table 3.1: Microarray Product Revenue: Arrays, Reagents and Instruments, 2005 and 2010; Table 3.2: Microarray Market Drivers; Table 3.3: Microarray Market Barriers; Table 3.4: Unit Pricing of DNA Microarrays, 2000-2010; Table 3.5: Steps in the Design and Implementation of a DNA Microarray Experiment; Table 3.6: Microarray Applications; Table 3.7: List of DNA Array Manufacturers; Table 4.1: Critical Factors for Microarray Content; Table 4.2: Top Three Suppliers of Treated Protein Microarray Surfaces for Self-Printing; Table 4.3: Top Suppliers of Commercially Available Protein Microarrays; Table 4.4: Top Suppliers of Protein Microarray Readers; Table 5.1: Affymetrix Sales of Probe Arrays, 2000-2007; Table 5.2: Affymetrix Total Product Sales, 1999-2007; Table 5.3: Affymetrix Instrument Sales, 2000-2007; Table 6.1: Microarray Genetic Testing; Table 6.2: ChIP-on-Chip Microarray Market Size Projections, 2005-2011; Table 8.1: Applications of Biochips by Class; Table 8.2: Diagnostics Microarray Market Size Projections, 2005-2011; Table 8.3: HTS Microarray Market Size Projections, 2005-2011; Table 8.4: Pharmacogenomics Microarray Market Size Projections, 2005-2011; Table 8.5: Toxicology Screening Microarray Market Size Projections, 2005-2011; Table 8.6: Expression Profiling Microarray Market Size Projections, 2005-2011; Table 9.1: Market Share of Microarray Products, 2006; Table 9.2: Affymetrix Product Sales; Table 9.3: Leading Microarray Companies; Table 9.4: Worldwide Microarray Market Size, 2004-2012; Table 9.5: Microarray Market Share by Technology Type; Table 9.6: DNA Microarray U.S. Market Size, 2005-2011; Table 9.7: DNA Microarray Worldwide Market Size, 2002-2011; Table 9.8: Biochip Market by Usage, 2003 and

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