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Gene Silencing Life Science Dashboard™ Series 1

Percepta Associates, Inc.
February 1, 2007
130 Pages - SKU: PCT2071689

Abstract Table of Contents Search inside this report Related Reports

RNA interference is rapidly emerging as a integral tool to the study of the physiological role of gene products. RNAi-based methods allow researchers to modulate and in many cases dramatically reduce expression of a gene of interest. Systems for delivering RNAs into cells for the purpose of gene silencing include standard transfection technologies as well as plasmid and viral systems for the inducible expression of siRNAs in vivo.

The Gene Silencing Dashboard™ was developed from responses to a 36-question survey completed by 367 scientists predominantly located in North America and Europe. This Dashboard reveals key market indicators for the gene silencing market as a whole as well as for the following methods representing market sub-segments:

RNAi screens using siRNA libraries (sets of 50 or more siRNAs)
Inducing siRNAs in vivo from a plasmid or other vector in cells
Delivering synthetic siRNAs into cells
Digesting long dsRNA in vivo using dicer or other enzymes
Expressing siRNA in vitro for delivery into cells
Using PCR mediated siRNA expression cassettes to generate siRNAs
Delivering siRNAs into cells by transfection
Delivering siRNAs into cells by electroporation
Delivering siRNAs into cells by viral infection
Using a reporter systems to track gene knockdown.

In order to dive more deeply into the characteristics and dynamics of the market for gene silencing products, Percepta has introduced the Gene Silencing Dashboard™, designed to take a snapshot of the current market landscape with the future goal of repeating and publishing the study to give Dashboard readers the ongoing story of how the market is adapting to new products, new competitors and new sales and marketing strategies.

Please note, the online download version is a global site license version of the report.

Executive Summary: Key Findings and Implications; Gene Silencing Dashboard; Gene Silencing Market Opportunity Matrix; Survey Methodology; Survey Invitation Text; Respondent Demographics; Frequency of Performance of Molecular Biology Techniques; Frequency of Performance of Gene Silencing Techniques; Reaction Throughput and Market Growth Rates; Respondent’s Stated Price Per Reaction; Total Market Size, Market Segment Sizes and Total Market Growth Rate; Market Shares by Segment (Share of Mention); Customer Satisfaction And Interest In Switching Suppliers; Product Features That Influence Purchasing Decisions; Primary Downstream Applications; Desired Changes to Gene Silencing Products; Survey Questionnaire
Figures and Tables: Figure 1: Respondent’s Place of Employment; Figure 2: Respondent’s Country/Region; Figure 3: Respondent’s Job Title; Figure 4: Respondent’s Areas of Expertise/Specialization; Figure 5: Number of Employees in Respondent’s Laboratories; Figure 6: Percentage of Respondents Performing Various Techniques at Least a Few Times per Year; Figure 7: Percentage of Respondents Performing RNAi/siRNA Experiments; Figure 8: Percentage of Respondents Performing Various Gene Silencing Techniques at Least a Few Times per Year; Figure 9: Percentage of Respondents That Perform RNAi Screens Using siRNA Libraries; Figure 10: Percentage of Respondents That Induce siRNAs in vivofrom a Plasmid or Other Vector in Cells; Figure 11: Percentage of Respondents That Deliver Synthetic siRNAs into Cells; Figure 12: Percentage of Respondents That Digest Long dsRNAin vivousing Dicer or Other Enzymes; Figure 13: Percentage of Respondents That Express siRNA in vitrofor Delivery into Cells; Figure 14: Percentage of Respondents That Use PCR Mediated siRNA Expression Cassettes to Generate siRNAs; Figure 15: Percentage of Respondents That Deliver siRNAs into Cells by Transfection; Figure 16: Percentage of Respondents That Deliver siRNAs into Cells by Electroporation; Figure 17: Percentage of Respondents That Deliver siRNAs into Cells by Viral Infection; Figure 18: Percentage of Respondents That Use a Reporter Systems to Track Gene Knockdown; Figure 19: Respondent's Primary Supplier for RNAi Screens Using siRNA Libraries; Figure 20: Respondent's Primary Supplier for Products to Induce siRNAs in vivofrom a Plasmid or Other Vector in Cells; Figure 21: Respondent's Primary Supplier for Products to Deliver Synthetic siRNAs into Cells; Figure 22: Respondent's Primary Supplier for Products to Digest Long dsRNAin vivousing Dicer or Other Enzymes; Figure 23: Respondent's Primary Supplier for Products to Express siRNA in vitrofor Delivery into Cells; Figure 24: Respondent's Primary Supplier for PCR Mediated siRNA Expression Cassettes to Generate siRNAs; Figure 25: Respondent's Primary Supplier for Products to Deliver siRNAs into Cells by Transfection; Figure 26: Respondent's Primary Supplier for Products to Deliver siRNAs into Cells by Electroporation; Figure 27: Respondent's Primary Supplier for Products to Deliver siRNAs into Cells by Viral Infection; Figure 28: Respondent's Primary Supplier of Reporter Systems to Track Gene Knockdown; Figure 29: Percentage of Respondents That Have Switched Suppliers in the Last Six Months; Figure 30: Most Important Features of Products for Gene Silencing Experiments; Figure 31: Respondent's Primary Downstream Application for RNAi Screens Using siRNA Libraries; Figure 32: Respondent's Primary Downstream Application for Products to Induce siRNAs in vivofrom a Plasmid or OtherVector in Cells; Figure 33: Respondent's Primary Downstream Application for Products to Deliver Synthetic siRNAs into Cells; Figure 34: Respondent's Primary Downstream Application for Products to Digest Long dsRNAin vivousing Dicer or OtherEnzymes; Figure 35: Respondent's Primary Downstream Application for Products to Express siRNA in vitrofor Delivery into Cells; Figure 36: Respondent's Primary Downstream Application for PCR Mediated siRNA Expression Cassettes to Generate siRNAs; Figure 37: Respondent's Primary Downstream Application for Products to Deliver siRNAs into Cells by Transfection; Figure 38: Respondent's Primary Downstream Application for Products to Deliver siRNAs into Cells by Electroporation; Figure 39: Respondent's Primary Downstream Application for Products to Deliver siRNAs into Cells by Viral Infection; Figure 40: Respondent's Primary Downstream Application for Reporter Systems to Track Gene Knockdown; Table 1: Frequency of Performance of Various Techniques; Table 2: Frequency of Co-Performance of Various Molecular Biology Techniques; Table 3: Frequency of Performance of Gene Silencing Methods; Table 4: Frequency of Co-Performance of Life Science Techniques with Gene Silencing Methods; Table 5: Frequency of Co-Performance of Gene Silencing Methods with Life Science Techniques; Table 6: Median and Average Monthly Throughput for Gene Silencing Products; Table 7: Percentage of Respondents Performing Various Numbers of Gene Silencing Reactions Per Month; Table 8: Projected Growth in the Performance of Various Gene Silencing Techniques; Table 9: Median and Average Price Per Prep for Gene Silencing Products; Table 10: Market Share Leaders for Gene Silencing Products; Table 11: Percentage of Respondents Satisfied with Various Gene Silencing Products and Reasons for Dissatisfaction; Table 12: Respondents Primary Application After Various Gene Silencing Methods

Gene Silencing Life Science Dashboard™ Series 1

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