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Gene Silencing Life Science Dashboard™ Series 2

Percepta Associates, Inc.
September 1, 2008
144 Pages - SKU: PCT2071682

Abstract Table of Contents Search inside this report Related Reports

RNA interference continues to emerge as a integral tool used to study the physiological role of gene products in vivo. RNAi-based methods allow researchers to modulate and in many cases virtually eliminate expression of a gene of interest. Systems for delivering RNAs into cells for the purpose of gene silencing include standard transfection technologies, both instrument-mediated and lipid-based, as well as plasmid and viral systems for the inducible expression of siRNAs in vivo.

Percepta’s 2008 Gene Silencing Dashboard™ dives deeply into the characteristics and dynamics of the market for gene silencing products. This 2008 Dashboard provides a snapshot of the current market landscape that can be compared with data from the 2007 Gene Silencing Dashboard, providing an ongoing story of how the market is adapting to new products, new competitors and new sales and marketing strategies.

The Gene Silencing Dashboard™ was developed from responses to a 21-question survey completed by 353 scientists predominantly located in North America and Europe. This Dashboard reveals key market indicators for the gene silencing market as a whole as well as for the following methods representing market sub-segments:

RNAi screens using siRNA libraries (sets of 50 or more siRNAs)
Inducing siRNAs in vivo from a plasmid or other vector in cells
Digesting long dsRNA in vivo using dicer or other enzymes
Expressing siRNA in vitro for delivery into cells
Using PCR mediated siRNA expression cassettes to generate siRNAs
Instrument mediated delivery of synthetic siRNAs into cells
Lipid mediated delivery of synthetic siRNAs into cells
Instrument mediated delivery of plasmids into cells for plasmid-based gene knockdown
Lipid mediated delivery of plasmids into cells for plasmid-based gene knockdown
Viral delivery of vectors into cells for vector-based gene knockdown
Using reporter systems to track gene knockdown

Please note, the online download version is a global site license version of the report.

Executive Summary: Key Findings and Implications; Gene Silencing Dashboard; Gene Silencing Market Opportunity Matrix; Survey Methodology; Survey Invitation Text; Respondent Demographics; Frequency of Performance of Life Science Techniques; Frequency of Performance of Gene Silencing Techniques; Reaction Throughput and Market Segment Growth Rates; Respondent’s Stated Price Per Reaction; Total Market Size, Market Segment Sizes and Total Market Growth Rate; Market Shares by Segment (Share of Mention); Customer Satisfaction And Interest In Switching Suppliers; Product Features That Influence Purchasing Decisions; Primary Downstream Applications; Desired Changes to Gene Silencing Products; Survey Questionnaire
Figures and Tables: Figure 1: Respondent’s Place of Employment; Figure 2: Respondent’s Country/Region; Figure 3: Respondent’s Job Title; Figure 4A: Respondent’s Areas of Expertise/Specialization; Figure 4B: Respondent’s Areas of Expertise/Specialization (Molecular Biology Excluded); Figure 5: Number of Employees in Respondent’s Laboratories; Figure 6: Percentage of Respondents Performing Various Life Science Techniques at Least a Few Times per Year; Figure 7: Percentage of Respondents Performing RNAi/siRNA Experiments; Figure 8: Percentage of Respondents Performing Various Gene Silencing Techniques at Least a Few Times per Year; Figure 9: Percentage of Respondents That Perform RNAi Screens Using siRNA Libraries; Figure 10: Percentage of Respondents That Induce siRNAs in vivofrom a Plasmid or Other Vector in Cells; Figure 11: Percentage of Respondents That Digest Long dsRNA in vivousing Dicer or other Enzymes; Figure 12: Percentage of Respondents that Express siRNA in vitro for Delivery into Cells; Figure 13: Percentage of Respondents that Use PCR Mediated siRNA Expression Cassettes to Generate siRNAs; Figure 14: Percentage of Respondents that Deliver Synthetic siRNAs into Cells (Instrument Mediated); Figure 15: Percentage of Respondents that Deliver Synthetic siRNAs into Cells (Lipid Mediated); Figure 16: Percentage of Respondents that Deliver Plasmids into Cells for Plasmid Based Gene Knockdown (Instrument Mediated); Figure 17: Percentage of Respondents that Deliver Plasmids into Cells for Plasmid Based Gene Knockdown (Lipid Mediated); Figure 18: Percentage of Respondents that Deliver Viral Vectors into Cells for Vector Based Gene Knockdown; Figure 19: Percentage of Respondents that Use a Reporter Systems to Track Gene Knockdown; Figure 20: Respondent’s Primary Supplier of Products for Performing RNAi Screens Using siRNA Libraries; Figure 21: Respondent’s Primary Supplier of Products to Induce siRNAs in vivofrom a Plasmid or Other Vector in Cells; Figure 22: Respondent’s Primary Supplier of Products to Digest Long dsRNA in vivo using Dicer or Other Enzymes; Figure 23: Respondent’s Primary Supplier of Products to Express siRNA in vitro for Delivery into Cells; Figure 24: Respondent’s Primary Supplier of PCR Mediated siRNA Expression Cassettes to Generate siRNAs; Figure 25: Respondent’s Primary Supplier of Products to Deliver Synthetic siRNAs into Cells (Instrument Mediated); Figure 26: Respondent’s Primary Supplier of Products to Deliver Synthetic siRNAs into Cells (Lipid Mediated); Figure 27: Respondent’s Primary Supplier of Products to Deliver Plasmids into Cells for Plasmid Based Gene Knockdown (InstrumentMediated); Figure 28: Respondent’s Primary Supplier of Products to Deliver Plasmids into Cells for Plasmid Based Gene Knockdown (Lipid Mediated); Figure 29: Respondent’s Primary Supplier of Products for Viral Delivery of Vectors into Cells for Vector Based Gene Knockdown; Figure 30: Respondent’s Primary Supplier of Reporter Systems to Track Gene Knockdown; Figure 31: Percentage of Respondents That Have Switched Suppliers in the Last Six Months; Figure 32: Most Important Features of Products for Gene Silencing Experiments; Figure 33: Respondent’s Primary Downstream Application for RNAi Screens Using siRNA Libraries; Figure 34: Respondent’s Primary Downstream Application for Products to Induce siRNAs in vivofrom a Plasmid or Other Vector in Cells; Figure 35: Respondent’s Primary Downstream Application for Products to Digest Long dsRNA in vivousing Dicer or Other Enzymes; Figure 36: Respondent’s Primary Downstream Application for Products to Express siRNA in vitrofor Delivery into Cells; Figure 37: Respondent’s Primary Downstream Application for PCR Mediated siRNA Expression Cassettes to Generate siRNAs; Figure 38: Respondent’s Primary Downstream Application for Products to Deliver Synthetic siRNAs into Cells (Instrument Mediated); Figure 39: Respondent’s Primary Downstream Application for Products to Deliver Synthetic siRNAs into Cells (Lipid Mediated); Figure 40: Respondent’s Primary Downstream Application for Products to Deliver Plasmids into Cells for Gene Knockdown (Instrument Mediated); Figure 41: Respondent’s Primary Downstream Application for Products to Deliver Plasmids into Cells for Gene Knockdown (Lipid Mediated); Figure 42: Respondent’s Primary Downstream Application for Products to Deliver Vectors into Cells for Vector Based Gene Knockdown; Figure 43: Respondent’s Primary Downstream Application for Reporter Systems to Track Gene Knockdown; Table 1: Respondent’s Areas of Expertise/Specialization Values for Figures 4A and 4B; Table 2: Frequency of Performance of Various Techniques; Table 3: Frequency of Co-Performance of Various Molecular Biology Techniques; Table 4: Frequency of Performance of Gene Silencing Methods; Table 5: Frequency of Co-Performance of Life Science Techniques with Gene Silencing Methods; Table 6: Frequency of Co-Performance of Gene Silencing Methods with Life Science Techniques; Table 7: Median and Average Monthly Throughput for Gene Silencing Products; Table 8: Percentage of Respondents Performing Various Numbers of Gene Silencing Reactions Per Month; Table 9: Comparison of to 2007 Percentage of Respondents Performing Various Numbers of Gene Silencing Reactions Per Month; Table 10: Projected Growth in the Performance of Various Gene Silencing Techniques; Table 11: Median and Average Price Per Prep for Gene Silencing Products; Table 12: Market Share Leaders for Gene Silencing Products; Table 13: Percentage of Respondents Satisfied with Various Gene Silencing Products and Reasons for Dissatisfaction; Table 14: Percentage of Respondents Satisfied with Various Gene Silencing Products: Comparison to 2007 Dashboard; Table 15: Most Important Features of Products for Gene Silencing Experiments -Comparison to 2007 Gene Silencing Dashboard; Table 16: Respondents Primary Application After Various Gene Silencing Methods; Table 17: Respondents Primary Application After Various Gene Silencing Methods -Comparison to 2007 Gene Silencing Dashboard

Gene Silencing Life Science Dashboard™ Series 2

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