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Drug Discovery Market Research Reports & Industry Analysis

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Drug Discovery Industry Research & Market Reports

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p53 Signaling Pathway in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... transcriptional activator of p53-regulated genes. This results in three major outputs; cell cycle arrest, cellular senescence or apoptosis. Other p53-regulated gene functions communicate with adjacent cells, repair the damaged DNA or set up positive and ...  |  read more...
USD 4,485
Pancreatic Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... drugs over the last years amount to another 128 drugs. Pancreatic Cancer Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 325 ...  |  read more...
USD 6,750
Peptides in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... number of ceased drugs over the last years amount to another 143 drugs. Peptides In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs ...  |  read more...
USD 6,750
Protein Kinase Inhibitors in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... three successful drugs are just the top of an emerging line of therapy. Given the fact that they all target tyrosine kinases and that kinase mutations can cause patients to become resistant to these drugs, ...  |  read more...
USD 6,750
Proteins in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... 944 developmental projects in cancer. In addition, there are 2 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 201 drugs. Proteins In Oncology Drug Pipeline Update lists ...  |  read more...
USD 6,750
Radiation Therapy in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... 741 developmental projects in cancer. In addition, there are 7 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 149 drugs. Radiation Therapy In Oncology Drug Pipeline Update ...  |  read more...
USD 6,750
RIG-I-like Receptor Signaling Pathway in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... a result of intracellular viral replication is recognized by a family of cytosolic RNA helicases termed RIG-I-like receptors (RLRs). There are today 75 companies plus partners developing 50 RIG-I-like receptor signaling pathway targeting drugs in ...  |  read more...
USD 2,250
Targeting Metabolic Pathways in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... drugs and the accumulated number of ceased drugs over the last years amount to another 91 drugs. Targeting Metabolic Pathways In Cancer Drug Pipeline Update lists all drugs and gives you a progress analysis on ...  |  read more...
USD 6,750
Targeting Tight Junctions in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... consisting of many different proteins that form large complexes. There are today 111 companies plus partners developing 106 tight junction targeting drugs in 447 developmental projects in cancer. In addition, there is 1 suspended drug ...  |  read more...
USD 4,485
The Latest Sales Figures in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... global pharmacuetical companies to progressive biotech companies. The analysis leverages the power of BioSeeker's 1stOncology intelligence which combines company disclosed product sales and detailed drug development information. The results is not only a unique insight ...  |  read more...
USD 4,485
TNF-Alpha Signaling Pathway in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... in 2523 developmental projects in cancer. In addition, there are 6 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 299 drugs. Tnf-Alpha Signaling Pathway In Oncology Drug ...  |  read more...
USD 6,750
Toll-Like Receptor Signaling Pathway in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... as homologs of Toll in Drosophila. Mammalian TLRs are expressed on innate immune cells, such as macrophages and dendritic cells, and respond to the membrane components of Gram-positive or Gram-negative bacteria. Pathogen recognition by TLRs ...  |  read more...
USD 6,750
Transcriptional Misregulation in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... and the accumulated number of ceased drugs over the last years amount to another 200 drugs. Transcriptional Misregulation In Cancer Drug Pipeline Update lists all drugs and gives you a progress analysis on each one ...  |  read more...
USD 6,750
TSLP Signaling Pathway in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... cells upon pathogen stimulation. TSLP can also activate dendritic cells, CD4+ T cells and CD8+ T cells. TSLP not only activate the JAK/STAT pathway but also induce phosphorylation of other signaling molecules including PI3K/Akt, ERK1/2 ...  |  read more...
USD 6,750
VEGF Signaling Pathway in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... signal transducer in both physiologic and pathologic angiogenesis. The binding of VEGF to VEGFR-2 leads to a cascade of different signaling pathways, resulting in the up-regulation of genes involved in mediating the proliferation and migration ...  |  read more...
USD 6,750
Viral Carcinogenesis Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... (HBV), hepatitis C virus (HCV), human papilloma virus (HPV), human T-cell lymphotropic virus (HTLV-1) and Kaposi's associated sarcoma virus (KSHV) contribute to 10-15% of the cancers worldwide. Via expression of many potent oncoproteins, these tumor ...  |  read more...
USD 6,750
Wnt Signaling Pathway in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... are today 211 companies plus partners developing 222 Wnt pathway targeting drugs in 885 developmental projects in cancer. In addition, there are 2 suspended drugs and the accumulated number of ceased drugs over the last ...  |  read more...
USD 6,750
Conjugated Drugs in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... targeting, the clinical application of ADCs is accelerating rapidly. But antibodies are not the only kind of compound one could conjugate small molecules to, nor the only class of compounds which one can yield targeted ...  |  read more...
USD 6,750
Cytokine Therapy in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... accumulated number of ceased drugs over the last years amount to another 11 drugs. Cytokine Therapy In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. ...  |  read more...
USD 4,485
ErbB Signaling Pathway in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... differentiation, cell motility, and survival. Ligand binding to the four closely related members of this RTK family -epidermal growth factor receptor (EGFR, also known as ErbB-1 or HER1), ErbB-2 (HER2), ErbB-3 (HER3), and ErbB-4 (HER4)-induces ...  |  read more...
USD 6,750
FSH Signaling Pathway in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... FSH signaling which continues further downstream. Activation of PKA leads to phosphorylation of transcription factors like cAMP response element binding protein(CREB) and brings about chromatin remodeling by phosphorylating histone H3. It also enhances the activity ...  |  read more...
USD 6,750
Gap Junctions in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... 'hemichannels', each containing six connexins, contributed by each neighboring cell. These channels permit the direct transfer of small molecules including ions, amino acids, nucleotides, second messengers and other metabolites between adjacent cells. Gap junctional communication ...  |  read more...
USD 6,750
Gene Therapy in Oncology Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... the accumulated number of ceased drugs over the last years amount to another 103 drugs. Gene Therapy In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of ...  |  read more...
USD 6,750
Head and Neck Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... accumulated number of ceased drugs over the last years amount to another 57 drugs. Head And Neck Cancer Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. ...  |  read more...
USD 6,750
HIF-1 Signaling Pathway in Cancer Drug Pipeline Update 2015
6/17/2015 | published by: BioSeeker Group AB
... (O(2)) and nutrient availability. The hypoxia-inducible factors (HIFs) are a common link between adaptation to low O(2), changes in cancer metabolism, and malignant progression. This report focusses around the cancer drugs targeting the hypoxia-inducible factor ...  |  read more...
USD 6,750
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