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Orthopedic Biomaterials, The World Market, 2nd Edition

Kalorama Information
September 1, 2007
150 Pages - SKU: KLI1399489

Abstract Table of Contents Search inside this report Related Reports

Countries covered: Global

Orthopedic biomaterial products, which can be organic or synthetic in nature, are implanted into or near a bone fracture to facilitate healing or to compensate for a lack or loss of bone tissue. Biomaterials used in orthopedic surgery include autografts, allografts, xenografts, ceramics, polymers, bone growth factors and synovial fluid substitutes. Among the prominent applications for orthopedic biomaterials are surface coatings for hip prostheses, bone cements, bone defect fillers, and fracture fixation plates.

Technological advancement and an aging, active population are the principal drivers behind the market for orthopedic biomaterials. Kalorama's Orthopedic Biomaterials, World Market, one of the few resources available on this market, looks at the Market for biomaterials, including the following segments:

Allograft Products (including DBM, Machined Bone and Standard Allograft)
Ceramic Products
Polymer Products
rhBMP Products
HA Viscosupplemental Products

As part of Kalorama Information's exhaustive coverage of the orthopedic biomaterials market for each area, the following data are provided:

Historical Revenues from 2001-2005
Forecasts to 2012
Competitive Market Share
Discussion of Issues and Trends
Review of New Products
Company Profiles

A truly global resource, this report provides information on the following world regions:

US
Europe
Asia
Rest of World

The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information.

For the purpose of this study, Kalorama Information conducted interviews with key industry officials, consultants, health care providers, orthopedic surgeons, research institutes, and government personnel. These sources were the primary basis for information specifically relating to trends in the orthopedic biomaterials industry, revenue and market share data presented in this report. Specific interviews with orthopedic implant device and biomaterial company representatives included marketing directors, division managers, and product representatives.

CHAPTER ONE: EXECUTIVE SUMMARY

Overview
Scope and Methodology
Musculoskeletal Conditions/Treatments
Prevelance of Musculoskeletal Conditions
Most Common Musculoskeletal Conditions
Joint Replacement Procedures
Future Directions in the Treatment of Musculoskeletal Conditions
Gene Therapy
Stem Cell Therapy
Orthopedic Biomaterials Products and Markets
World Orthopedic Biomaterials Market
Market Segment Analysis
Allograft Bone Substitutes
Ceramic Bone Substitutes
Polymer Bone Substitutes
rhBMP
HA Viscosupplemental Substitutes

CHAPTER TWO: INTRODUCTION

Overview of the Form/Function of Bone

Bone Characteristics

Types of Bone

Cortical Bone

Cancellous Bone

Bone Cells

Osteoblasts

Osteoclasts

Osteocytes

The Functions of Bone

Bone Matrix

Joint Components

Cartilage

Joint Capsule

Synovium

Ligaments

Prevalence of Musculoskeletal Conditions

Musculoskeletal Conditions In Europe

Musculoskeletal Conditions In the United States

Common Musculoskeletal Conditions

Osteoarthritis

Osteoporosis

Bone Fractures

Ligament Injuries

Joint Replacement Procedures

Introduction

Most Common Procedures

Knee Reconstruction

Hip Reconstruction

Spinal Fusion

Future Directions in the treatment of Musculoskeletal conditions

Gene Therapy

Stem Cell Therapy CHAPTER THREE: ORTHOPEDIC BIOMATERIALS

Overview
Brief History of Orthopedic Biomaterials
Categories of Orthopedic Biomaterials
Bone Grafts
Types of Bone Grafts
Autografts
Advantages
Disadvantages
Allograft
Disadvantages
Xenografts
Disadvantages
Allograft Bone Graft Substitutes
Overview
Demineralized Bone Matrix
Types of DBM Products
Conventional Allograft
Machined Allograft
Ceramic-based Bone Graft Substitutes
Overview
Types of Materials
Hydroxyapatites
Ceramic Coated Joint Implants
Coralline Hydroxyapatite
Tricalcium Phosphate
Calcium Phosphate
Calcium Sulphate
Polymer-based Bone Graft Substitutes
Overview
Nondegradable Polymers
Bioabsorbable Polymer Biomaterials
Polylactic Acid (PLA)
Polyglycolic Acid (PGA)
Copolymers
Factor-based Bone Graft Substitutes
Overview
Types of Growth Factors
Bone Morphogenic Protein (BMP)
Transforming Growth Factor-Beta (TGF-â)
Fibroblast Growth Factors (FGFs)
Insulin-Like Growth Factors (IGFs)
Platelet-Derived Growth Factor (PDGF)
Carriers/Delivery Systems for Growth Factors
Type-1 Collagen
Demineralized Bone Matrix (DBM)
Polymers
Ceramics
Hyaluronic Acid
Gene Therapy
Hyaluronic Acid Synovial Fluid Substitute
Overview
Viscosupplementation

CHAPTER FOUR: ORTHOPEIC BIOMATERIAL MARKET ANALYSIS

World Market Analysis and Forecast

Orthopedic Biomaterial Market Drivers

Orthopedic Biomaterials Market Forecast

World Regional Markets

Market Segment Analysis

Market Value and Growth by Segment

Allograft Bone Market Analysis

Allograft Applications

Allograft Bone Products

DBM

Machined Bone Products

Allograft Market

Market Drivers and Limitations

Allograft Competitors’ Market Share

Ceramic Bone Substitute Market Analysis

Ceramic Applications and Products

Ceramic-coated Implants

Ceramic-based Bone Substitute Products

Ceramic Biomaterials Market

Market Drivers and Limitations

Ceramic Competitors’ Market Share

Polymer Bone Substitutes Market Analysis

Nondegradable Polymers

PEEK Applications

Bioabsorbable Polymers

Applications for Polymer Bioabsorbable Biomaterials

Bioaborable Polymers as Delivery Systems

Combination Products

Polymer Biomaterials Market

Market Drivers

Competitors’ Market Share

Bone Morphogenetic Proteins Market Analysis

Products and Applications

InFuse and InductOS (RhBMP-2)

OP-1 (rhBMP-7)

Carrier Materials for BMPs

BMP World Market

Market Drivers

HA Viscosupplementational Market Analysis

HA Viscosupplemental Products and Applications

HA Viscosupplementational Market

Market Drivers

HA Viscosupplemental Competitors’ Market Share CHAPTER FIVE: COMPANY PROFILES

Biomet, Inc.
Genzyme Corporation
IsoTis OrthoBiologics, Inc.
LifeCell Corporation
Medtronic Sofamor Danek, Inc.
Orthovita, Inc.
Osteotech, INC.
Smith & Nephew, Inc.
Stryker Corporation
Synthes, Inc
Tutogen Medical, Inc.
Wright Medical Group, Inc. TABLE OF EXHIBITS Exhibit 1-1: World Orthopedic Biomaterials Market
Exhibit 1-2 World Orthopedic Biomaterials Market (in millions of dollars)
Exhibit 1-3: Segment Market Share, 2006 (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
INTRODUCTION
Exhibit 2-1: Emergency Room Visits for Muscolskeletal Symptoms, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-2: Emergency Room Visits for Fractures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-3: Knee Replacement Procedures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-4 Hip Replacement Procedures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
Exhibit 2-5: Spinal Fusion Procedures, 1998-2004 (Procedure, Year, Number of Patients, Number of Procedures, Mean Age of Patient, Mean Length of Stay)
ORTHOPEDIC BIOMATERIAL MARKET ANALYSIS
Exhibit 4-1: World Orthopedic Biomaterials Market
Exhibit 4-2: World Regional Biomaterials Markets by Revenue, 2006
Exhibit 4-3 World Regional Biomaterilas Markets by Percentage, 2006
Exhibit 4-4: Orthopedic Biomaterials Market by Segment (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
Exhibit 4-5: Segment Market Share in 2006 (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
Exhibit 4-6: Segment Market Share in 2012 (Allograft Products, Ceramic Products, Polymer Products, rhBMP Products, HA Viscosupplemental Products)
Exhibit 4-7: Sample Allograft Distribution Relationships (Tissue, Source, Processor, Distributor)
Exhibit 4-8: Selected Allograft Prdoucts on the Market v Exhibit 4-9: World Allograft Market
Exhibit 4-10: Allograft Product Categories, by Percent, 2006 (DBM, Machined Bone, Standard Allograft)
Exhibit 4-11: Allograft Market Share, 2006
Exhibit 4-12: Selected Ceramic-Based Biomaterials (Product, Manufacturer, Description)
Exhibit 4-13: World Market for Ceramic-Based Biomaterials
Exhibit 4-14: Ceramic-Based Products Market Share,2006
Exhibit 4-15: Selected Polymer Products (Product, Composition, Company)
Exhibit 4-16: Bioresorbable Polymer Resorption (Polymer, Crystallinity, Beginning of Resorption, Time of Complete Resorption)
Exhibit 4-17: World Polymer Biomaterials Market (millions)
Exhibit 4-18: Polymer Biomaterials Market Share, 2006
Exhibit 4-19: Various Carrier Materials Available for BMPs
Exhibit 4-20: The World Market for rhBMP Products
Exhibit 4-21 Osteoporosis and Low Bone Mass in the United States
Exhibit 4-22 Definitions and Charactertistics of Hyaluronic Acid and Hylans
Exhibit 4-23 Osteoporosis and Low Bone Mass in the United States
Exhibit 4-24: Selected HA Viscosupplemental Products
Exhibit 4-25: World HA Viscosupplementational Market (in millions of dollars)
Exhibit 4-26: World Viscosupplementation Market Share, 2006

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