Countries covered: United States
Despite nine years of intensive RDT&E and bio-terror mitigation programs implementation, at a cost of more than $50 billion, virtually all significant targets are as vulnerable to biological terror today as they were in September 2001.
In the words of President Obama: “we know that the successful deployment of a biological weapon - whether it is sprayed into our cities or spread through our food supply - could kill tens of thousands of Americans and deal a crushing blow to our economy. ”Meeting this challenge will require, among other things, shortening the bio-attack alarm response time, premium detection sensitivity and selectivity at a reasonable cost of ownership.
We forecast that over the next five years, led by 3rd generation technologies the US bio-detection market (including systems sale, service, consumables and upgrades) will grow from $1.3 billion in 2010 to $2.6 billion by 2016.
With more than 210 pages, 41 tables and 77 figures, granulated into more than 90 sub-markets this report represents a comprehensive bio-detection technologies and markets.
The report delves into:
- Market by systems sales, upgrade and service markets
- Market by first, second and third generation technologies
- Market by indoor, outdoor, hand-held and mobile labs segment
- Market by end user (e.g. 1st responders)
- Systems prices
- Installed base by product and user categories
- Leading US bio-security projects
- 27 vendors and their products
- Current and pipeline technologies (e.g. advanced collectors-concentrators, reagent-less triggers, DNA-based diagnostics, antigen/anti-body methods, signal analysis algorithms)
- Competitive analysis (e.g. barriers to entry, barriers to substitution, competitive rivalry)
- Business opportunities (e.g. emerging threats, human and animal sentinel surveillance, reagent-less detection assays, IC3 compatibility)
- SWOT analysis
- Market drivers and inhibitors
- And more…
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- 1 Executive Summary
- 1.1 Main Findings
- 1.2 Main Conclusions
- 1.3 Bio-Detection Market Forecast - 2011-2016
- 1.3.1 Overview
- 1.3.2 Systems and Service & Upgrade Markets - 2011-2016
- 1.3.3 Systems & Service Market by Modality - 2011-2016
- 1.3.4 Systems & Service Market by Technology Generation - 2011-2016
- 1.4 Bio-Detection - Next Generation Business Opportunities
- 1.5 Technologies Outlook
- 2 Introduction
- 2.1 Scope
- 2.2 Methodology
- 2.2.1 Research Methods
- 2.2.2 Report Structure
- 2.2.3 Assumptions
- 2.3 Who is This Report For?
- 3 Bio-Detection Market - Drivers
- 4 Bio-Detection Market - Inhibitors
- 5 Bio-Detection Industry Competitive Analysis
- 6 Bio-Detection Industry SWOT Analysis
- 7 Bio-detection Market Dynamics
- 8 Defending Against Bioterrorism
- 8.1 Definition of Bioterrorism
- 8.2 The Threat of Bioterrorism
- 8.3 How Real Is The Bioterrorism Threat?
- 8.4 Bio-Defense Programs
- 8.4.1 Strategy
- 8.4.2 Project BioWatch
- 8.4.3 Project BioSense
- 8.4.4 Project BioShield
- 8.5 Bio-Detection - The Industry
- 9 The Obama Administration Bio Terror Mitigation Strategy
- 9.1 Biosurveillance Network
- 9.2 Bio-Defense Funding
- 9.2.1 Overview
- 9.2.2 DHHS Bio-Defense Missions and Funding
- 9.2.3 DHS Bio-Defense Missions and Funding
- 9.2.4 DOD Bio-Defense Missions and Funding
- 9.2.5 DOA Bio-Defense Missions and Funding
- 9.2.6 EPA Bio-Defense Missions and Funding
- 9.3 The Obama Administration Bio-Defense Strategy
- 10 Bio-Detection - Technologies Overview
- 10.1 Bio-Detection Technology Challenges
- 10.1.1 Sampling the Environment
- 10.2 The Bio-Detection Process
- 10.2.1 Bio-Detectors in a Multitude of Ambient Settings
- 10.2.2 Bio-Detection Triggering
- 10.2.3 Collection of Particles
- 10.2.4 Bio-Particle Detectors
- 10.2.5 Bio-Agent Identification
- 11 Major Bio-Detection Technological Challenges
- 11.1 Challenge 1 - Detection of Small Particle Concentration
- 11.2 Challenge 2 - Eliminating Bio Background
- 11.3 Challenge 3 - Expensive Reagents
- 11.4 Challenge 4 - Expensive Equipment Maintenance
- 11.5 Challenge 5 - Adapting Equipment to Changing Environments
- 11.6 Challenge 6 - Dealing With Emerging Threats
- 12 Bio Detection Technologies Review & Outlook - 2011-2016
- 12.1 Bio-Detection - Core Technologies Comparison
- 12.2 Collector/Concentrator Core Technologies
- 12.3 Cyclone Collectors
- 12.4 Variable Particle-Size Impactor
- 12.5 Virtual Impactors
- 12.6 Impingers
- 12.7 Reagentless Trigger Core Technologies
- 12.7.1 Flow Cytometry
- 12.7.2 Particle Sizing
- 12.7.3 Gas Chromatography
- 12.7.4 Trigger Technologies - Drivers
- 12.7.5 Trigger Technologies - Inhibitors
- 12.8 DNA Based Diagnostic Core Technologies
- 12.8.1 Overview of DNA-Based Detection
- 12.8.2 Polymerase Chain Reaction (PCR)
- 12.8.3 DNA / RNA Microarrays
- 12.8.4 DNA Technology Drivers
- 12.8.5 DNA Technology Inhibitors
- 12.9 Antibody-Antigen Diagnostic Core Technologies
- 12.9.1 Overview of Antibody-Antigen Reaction
- 12.9.2 Hand-Held Immuno-Chromatographic Assays (HHA)
- 12.9.3 Magnetic Microbead-Base Assays
- 12.9.4 Microfluidic Devices - “Lab on a Chip”
- 12.9.5 Fluorescence Imaging
- 12.9.6 Electrochemical-Luminescence (ECL)
- 12.9.7 Antibody/Antigen Technology - Drivers
- 12.9.8 Antibody/Antigen Technology - Inhibitors
- 12.1 Signal Analysis Algorithms
- 12.10.1 Clustering / Classifier Algorithms
- 12.10.2 Image Analysis Algorithms
- 12.10.3 Decision Algorithms
- 12.10.4 Algorithm Drivers
- 12.10.5 Algorithm Inhibitors
- 12.11 Rapid Microbiological Technologies
- 13 Biological Detection - Overview by Application
- 13.1.1 Application 1 - Emergency Responder Hand-Held Detectors
- 13.1.2 Application 2 - Emergency Responder Mobile Labs
- 13.1.3 Application 3 - Indoor Standoff Detectors
- 13.1.4 Application 4 - Outdoor Standoff Detectors
- 14 U.S. Bio-Detection Systems Market Outlook - 2011-2016
- 14.1 Methodology
- 14.2 Bio-Detection Systems Sales - 2011-2016
- 14.2.1 Bio-Detection Systems Revenue Sales by Generation Forecast - 2011-2016
- 14.2.2 Bio-Detection Systems Sales by Modality - 2011-2016
- 14.3 Bio-Detection Systems Quantity Sales - 2011-2016
- 14.3.1 Bio-Detection Systems Quantity Sales by Generation - 2011-2016
- 14.3.2 Bio-Detection Systems Quantity Sales by Modality - 2011-2016
- 14.4 Outdoor Bio-Detection Systems Market - 2011-2016
- 14.4.1 Outdoor Standoff Detection Systems Revenue Sales Outlook - 2011-2016
- 14.4.2 Outdoor Standoff Detection Systems Quantity Sales Outlook - 2011-2016
- 14.5 Indoor Bio-Detection Systems Market- 2011-2016
- 14.5.1 Indoor Standoff Systems Detection Sales - 2011-2016
- 14.5.2 Indoor Standoff Systems Unit Sales - 2011-2016
- 14.6 First Responder Hand-Held Bio-Detection Systems Market - 2011-2016
- 14.6.1 First Responder Hand-Held Systems Sales - 2011-2016
- 14.6.2 First Responder Hand-Held Systems Quantity Sales - 2011-2016
- 14.7 Mobile Bio-Detection Labs Market - 2011-2016
- 14.7.1 First Responder Mobile Labs Sales - 2011-2016
- 14.7.2 First Responder Mobile Labs Quantity Sales - 2011-2016
- 15 Service & Upgrade Business - 2011-2016
- 15.1 Bio-Detection Service & Upgrade Business by Modality - 2011-2016
- 15.2 Bio-Detection Service Business by Technology Generation - 2011-2016
- 16 Business Opportunities in Bio-Detection - 2011-2016
- 16.1 Historical Perspective
- 16.1.1 A Market Waiting for Transition
- 16.1.2 The Current and Future HLS Bio-Defense Strategy for Detection
- 16.1.3 Factors Affecting Biological Detectors Deployment and Technologies - 2011-2016
- 16.1.4 Biological Detection Technology Timeline
- 16.2 Next Generation HLS Bio-Detection Systems Business Opportunities
- 16.2.1 Overview
- 16.2.2 Business Opportunity 1 - Emerging Threats
- 16.2.3 Business Opportunity 2 - Human Sentinel Surveillance System
- 16.2.4 Business Opportunity 3 - Animal Sentinel Surveillance System
- 16.2.5 Business Opportunity 4 - Biological IC3 - Biological Threat Assessment Intelligence Command, Control, and Communication Infrastructure
- 16.2.6 Business Opportunity 5 - Reducing False Alarms - Lesser False Positives and False Negatives
- 16.2.7 Business Opportunity 6 - Reducing Cost - Minimizing Use of Non-Reusable Reagents
- 16.3 Outdoor Standoff Biological Detectors
- 16.3.1 Business Opportunity 7 - Bioagent Autonomous Networked Detectors (BAND)
- 16.3.2 Business Opportunity 8 - Rapid Automated Biological Identification System (RABIS)
- 16.3.3 Business Opportunity 9 - First Responder Portable Hand-Held Detector
- 16.3.4 Business Opportunity 10 - First Responder Mobile Biological Detection Station
- 16.3.5 Business Opportunity 11 - Regional Automatic Detector - Outdoor Standoff Detectors
- 16.3.6 Business Opportunity 12 - Networked Automatic Detector - Indoor Standoff Detectors
- 16.3.7 Business Opportunity 13 - External Spread of Bioagent Detection
- 16.3.8 Business Opportunity 14 - Internal Spread of Bioagent
- 16.4 Other Bio-Detection Technologies - Business Opportunities
- 16.4.1 Business Opportunity 15 - “Lab on a Chip” - Miniature Detection Devices
- 16.4.2 Business Opportunity 16 - Reagentless Specific Detection Assays
- 16.4.3 Business Opportunity 17 - Laser Induced Breakdown Spectroscopy (LIBS)
- 16.4.4 Business Opportunity 18 - Raman Spectroscopy-based Reagentless Detection
- 16.5 Future Technologies and Systems
- 17 Bio-Detection - Personnel Considerations
- 17.1 Background - Personnel
- 17.2 Personnel Training
- 18 Vendors
- 18.1 20/20 GeneSystems Inc.
- 18.2 Advnt Biotechnologies
- 18.3 Agilent Technologies
- 18.4 Alexeter Technologies
- 18.5 ANP Technologies, Inc.
- 18.6 BAS - Biological Alarm Systems Ltd. (Israel)
- 18.7 BD Biosciences Immunocytometry Systems
- 18.8 Bertin Technologies
- 18.9 BioDefense Corporation
- 18.1 BioDETECT AS
- 18.11 BioSentinel Pharmaceuticals LLC
- 18.12 3M Microbiology (Biotrace International, Ltd.)
- 18.13 BioTraces, Inc.
- 18.14 BioVeris Corporation
- 18.15 Biral
- 18.16 Cepheid
- 18.17 Commonwealth Biotechnologies, Inc.
- 18.18 Dycor Technologies Ltd.
- 18.19 Environics Oy
- 18.2 Evogen, Inc.
- 18.21 General Dynamics Canada
- 18.22 GenPrime, Inc.
- 18.23 Groton Biosystems
- 18.24 Haztech Systems, Inc.
- 18.25 Idaho Technology, Inc.
- 18.26 JMAR Technologies, Inc.
- 18.27 New Horizons Diagnostics
- 18.28 Proengin
- 18.29 QTL Biodetection
- 18.3 Research International
- 18.31 Response Biomedical
- 18.32 Roche Applied Science
- 18.33 Smiths Detection
- 18.34 Tetracore, Inc.
- 19 Prices of Bio-Detection Equipment
- 20 Appendix A: The Threat of Bioweapons
- 20.1 Use of Bioweapons - Historical Perspective
- 20.2 Biological Terror - Bacterial Agents
- 20.2.1 Anthrax
- 20.2.2 Cholera
- 20.2.3 Plague
- 20.2.4 Tularemia
- 20.3 Biological Terror - Viral Agents
- 20.3.1 Smallpox
- 20.3.2 Hemorrhagic Fever Viruses
- 20.3.3 Venezuelan Equine Encephalitis
- 20.4 Biological Terror - Rickettsiae Agents
- 20.4.1 Q Fever
- 20.4.2 Typhus
- 20.5 Biological Terror - Toxins
- 20.5.1 Botulinum Toxin
- 20.5.2 Ricin
- 20.5.3 Saxitoxin
- 20.5.4 Staphylococcal Enterotoxin B (SEB)
- 21 Appendix B: Legal Issues
- 21.1 International / European Legislation / Agreements
- 21.1.1 The Biological and Toxin Weapons Convention (BTWC) 1972
- 21.2 U.S. Bioterrorism Legislation
- List of Tables
- Table 1 - US HLS & Defense Bio-Detection Systems and Service Market [$M] 2010 & 2016 - by Product Classification
- Table 2 - U.S. HLS Bio-Detection Systems and Service Market Forecast [$ Million] - 2010-2016
- Table 3 - U.S. HLS Bio-Detection Systems & Service (S&S) Market Forecast by Expenditure Share [%] - 2010-2016
- Table 4 - U.S. HLS Bio-Detection Systems & Service Market by Portability [$ Million] - 2010-2016
- Table 5 - U.S. HLS Bio-Detection Systems & Service Market by Modality Share [%] - 2010-2016
- Table 6 - Bio-Detection Systems Sales by Generation [$ Million] - 2010-2016
- Table 7 - Bio-Detection Systems Sales by Generation [%] - 2010-2016
- Table 8 - Bio-Detection Service and Upgrade Business Forecast by Technology Generation [$ Million] - 2010-2016
- Table 9 - Bio-Detection Service and Upgrade Business Forecast by Technology Generation Share [%] - 2008-2014
- Table 10 - Evolution of Bio-detection Market Dynamics - 2010-2014
- Table 11 - U.S. Federal HLS-HLD Bio-Defense Funding [$ Million], by Agency - FY2001-FY2011
- Table 12 - Comparison of Attributes of Bio-Detection Technologies
- Table 13 - Bio-Detection Systems Sales by Generation [$ Million] - 2010-2016
- Table 14 - Bio-Detection Systems Sales by Generation Share [%] - 2010-2016
- Table 15 - Bio-Detection Consolidated Sales by Modality [$M] - 2010-2016
- Table 16 - Bio-Detection Systems Sales by Modality Share [%] - 2010-2016
- Table 17 - Bio-Detection Systems Quantity Sales by Generation [Units] - 2010-2016
- Table 18 - Bio-Detection Systems Quantity Sales by Generation Share [%] - 2010-2016
- Table 19 - Bio-Detection Systems Quantity Sales by Modality [Units] - 2010-2016
- Table 20 - Bio-Detection Systems Quantity Sales by Modality Share [%] - 2010-2016
- Table 21 - Outdoor Standoff Detectors Systems Sales by Generation [$ Million] - 2010-2016
- Table 22 - Outdoor Standoff Detectors Systems Sales by Generation Share [%] - 2010-2016
- Table 23 - Outdoor Standoff Detectors Systems Sales [Units] - 2010-2016
- Table 24 - Outdoor Standoff Detectors Systems Sales Share [%] - 2010-2016
- Table 25 - Indoor Standoff Systems Sales by Generation [$M] - 2010-2016
- Table 26 - Indoor Standoff Detectors Systems Sales by Generation Share [%] - 2010-2016
- Table 27 - Indoor Standoff Systems Sales by Generation [Units] - 2010-2016
- Table 28 - Indoor Standoff Detectors Systems Sales by Generation Share [%] - 2010-2016
- Table 29 - First Responder Hand-Held Detection Systems Sales [$M] by Generation - 2010-2016
- Table 30 - First Responder Hand-Held Detection Systems Sales by Generation Share [%] - 2010-2016
- Table 31 - First Responder Hand-Held Systems Sales [Units] by Generation - 2010-2016
- Table 32 - First Responder Hand-Held Systems Sales by Generation Share [%] - 2010-2016
- Table 33 - First Responder Mobile Labs Sales by Generation [$M] - 2010-2016
- Table 34 - First Responder Mobile Labs Sales by Generation Share [%] - 2010-2016
- Table 35 - First Responder Mobile Labs Sales by Generation [Units] - 2010-2016
- Table 36 - First Responder Mobile Labs Unit Sales by Generation Share [%] - 2010-2016
- Table 37 - Bio-Detection Service & Upgrade Business by Modality [$M] - 2010-2016
- Table 38 - Bio-Detection Service & Upgrade Business by Modality Share [%] - 2010-2016
- Table 39 - Bio-Detection - Service Business by Technology Generation [$M] - 2010-2016
- Table 40 - Bio-Detection Service Business Forecast by Technology Generation Share [%] - 2010-2016
- Table 41 - Prices of Bio-Detection Equipment
- List of Figures
-
- Figure 1 - Cumulative Civilian Biodefense Funding by Agency, FY2001-FY2011 [$M]
- Figure 2 - US HLS & Defense Bio-Detection Systems and Service Market [$M] 2010 & 2016 - by Product Classification
- Figure 3 - U.S. HLS Bio-Detection Systems & Service Market [$ Million] - 2010-2016
- Figure 4 - U.S. HLS Bio-Detection Systems & Service Market Share [%] - 2010, 2013 & 2016
- Figure 5 - U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality [$ Million] - 2010-2016
- Figure 6 - U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality Share [%] - 2010, 2013 & 2016
- Figure 7 - Bio-Detection Systems Sales by Generation [$ Million] - 2010-2016
- Figure 8 - Bio-Detection Service Business by Technology Generation [$ Million] - 2010-2016
- Figure 9 - Types of Biological Detectors
- Figure 10 - Bio-Detection Industry Competitive Analysis
- Figure 11 - Bio-Detection Industry SWOT Analysis
- Figure 12 - Bio-Detection Strategy - Three Pillars Diagram
- Figure 13 - BioShield Timeline and Funding
- Figure 14 - Bio-Detection Responsibilities across the US Federal Bio-surveillance Network
- Figure 15 - U.S. Government HLS-HLD Bio-Defense Funding [$ Million] - FY2001-FY2011
- Figure 16 - Cumulative 2001-2011 Bio-Defense Funding [$Million], by Agency
- Figure 17 - Bio-Defense Funding Share [%], by Agency - 2001, 2006 & 2011
- Figure 18 - Comparison in Weight of Pathogens Between BW Agents and CW Agents [mg]
- Figure 19 - Typical Point Detection Automated Architecture (With a Combined Trigger/Cue)
- Figure 20 - Airborne Bacterial Concentration Fluctuation in a Single Day
- Figure 21 - Cross-Section of Cascade Impactor: PIXE International Corporation
- Figure 22 - TSI’s Model 3317 System with Concentrator, GPS Receiver & Wireless Data Radio
- Figure 23 - Biological Detection Technologies - 2010-2016
- Figure 24 - Flow Cytometry
- Figure 25 - Gas Chromatography
- Figure 26 - Polymerase Chain Reaction
- Figure 27 - RT-PCR
- Figure 28 - Principles of Real-Time PCR
- Figure 29 - DNA Microarrays - Principles of Operation
- Figure 30 - Schematic for Antibody Protein
- Figure 31 - Hand Held Detectors: Alexeter Guardian Reader System and Tetracore Test Strips
- Figure 32 - Roche Applied Science - Light CyclerTM Model 1.2
- Figure 33 - Bio-Detection Systems Sales by Generation [$M] - 2010-2016
- Figure 34 - Bio-Detection Systems Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 35 - Bio-Detection Systems Sales by Modality [$M] - 2010-2016
- Figure 36 - Bio-Detection Systems Sales by Modality Share [%] - 2010, 2013 & 2016
- Figure 37 - Bio-Detection Systems Quantity Sales by Generation [Units] - 2010-2016
- Figure 38 - Bio-Detection Systems Quantity Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 39 - Bio-Detection Systems Quantity Sales by Modality [Units] - 2010-2016
- Figure 40 - Bio-Detection Systems Quantity Sales by Modality Share [%] - 2010, 2013 & 2016
- Figure 41 - Outdoor Systems Standoff Detectors Sales by Generation [$M] - 2010-2016
- Figure 42 - Outdoor Standoff Detectors Systems Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 43 - Outdoor Standoff Detectors Systems Sales [Thousand of Units] - 2010-2016
- Figure 44 - Outdoor Standoff Detectors Systems - Sales Share [%] - 2010, 2013 & 2016
- Figure 45 - Indoor Standoff Detectors Systems Sales by Generation [$M] - 2010-2016
- Figure 46 - Indoor Standoff Detectors Systems Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 47 - Indoor Standoff Systems Sales by Generation [Units] - 2010-2016
- Figure 48 - Indoor Standoff Systems Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 49 - First Responder Hand-Held Detection Systems Sales [$M] by Generation - 2010-2016
- Figure 50 - First Responder Hand-Held Detection Systems Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 51 - First Responder Hand-Held Detection Systems Sales by Generation [Units] - 2010-2016
- Figure 52 - First Responder Hand-Held Detection Systems Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 53 - First Responder Mobile Labs Sales by Generation [$M] - 2010-2016
- Figure 54 - First Responder Mobile Labs Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 55 - First Responder Mobile Labs Sales by Generation [Units] - 2010-2016
- Figure 56 - First Responder Mobile Labs Unit Sales by Generation Share [%] - 2010, 2013 & 2016
- Figure 57 - Bio-Detection Service & Upgrade Business Forecast by Modality [$M] - 2010-2016
- Figure 58 - Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] - 2010, 2013 & 2016
- Figure 59 - Bio-Detection Service & Upgrade Business by Technology Generation [$M] - 2010-2016
- Figure 60 - Bio-Detection Service & Upgrade Business by Technology Generation [%] - 2010, 2013 & 2016
- Figure 61 - Factors Affecting Biological Detection Deployment and Technologies - 2010-2016
- Figure 62 - Bio-Detection Timeline
- Figure 63 - Civilians in China During the SARS Epidemic
- Figure 64 - A Typical Microfluidic Device
- Figure 65 - BAS101 Scheme
- Figure 66 - The Spraying of Anthrax from Aum Shinrikyo’s Headquarters June 1993
- Figure 67 - Anthrax Spores and Disease
- Figure 68 - Cholera Bacteria
- Figure 69 - Pneumonic Plague - The Disease
- Figure 70 - Tularemia - The Disease
- Figure 71 - Smallpox Virus And Disease
- Figure 72 - Ebola Virus - Electron Microscopy Image
- Figure 73 - VEE - Venezuelan Equine Encephalitis Virus in the Olfactory Mucosa of a Mouse
- Figure 74 - Q Fever
- Figure 75 - Typhus Microbe - Electron Microscopy Image
- Figure 76 - Castor Plant And Structure For The Ricin Toxin
- Figure 77 - The Dinoflagellate Alexandrium Tamarense And Structure of Saxitoxin
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