Zollinger-Ellison Syndrome (Gastrinoma) Global Clinical Trials Review, H1, 2013

GlobalData
March 31, 2013
72 Pages - SKU: GBDT5014102
Hematological Cancers Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
Unmet needs across the hematological malignancies remain high, with most traditional therapies conferring low levels of specificity and high toxicity. There are today 485 companies plus partners developing 752 hematological cancer drugs in 1767 developmental projects  |  read more...
USD 8,996
The MAPK Signaling Pathway in Oncology Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. There are today 250 companies plus partners developing 311 The MAPK signaling  |  read more...
USD 6,746
TNF-Alpha Signaling Pathway in Oncology Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
The TNF-alfa signaling pathway stimulates the MAPK signaling module and activates NFkB. There are today 386 companies plus partners developing 507 TNF-alpha pathway targeting drugs in 2119 developmental projects in cancer. In addition, there are 6  |  read more...
USD 6,746
PI3K-Akt Signaling Pathway in Cancer Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
The phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, translation, proliferation, growth, and survival. There are today 496 companies plus  |  read more...
USD 8,996
HIF-1 Signaling Pathway in Cancer Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
Cancer cells are characterized by rapid proliferation and require adaptive metabolic responses to allow continued biosynthesis and cell growth in the setting of decreased oxygen (O(2)) and nutrient availability. The hypoxia-inducible factors (HIFs) are a  |  read more...
USD 6,746
ID Signaling Pathway in Oncology Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
Inhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA binding capacity. This family  |  read more...
USD 2,246
Interfering With the ECM-Receptor Interaction for the Treatment of Cancer Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
The extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell and tissue structure and function. There  |  read more...
USD 2,246
Leptin Signaling Pathway in Oncology Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
The binding of Leptin to its receptor, LEPR induces various signaling modules such as JAK/STAT, RAS/RAF/MAPK, IRS/PI-3K and AMPK/ACC. There are today 292 companies plus partners developing 361 Leptin pathway targeting drugs in 1445 developmental projects  |  read more...
USD 6,746
Liver Cancer Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
There are today 183 companies plus partners developing 219 drugs targeting liver cancer in development. In addition, there is 1 suspended drug and the accumulated number of ceased drugs over the last years amount to  |  read more...
USD 4,496
Lymphoma Drug Pipeline Update 2015
1/5/2015 | published by: BioSeeker Group AB
Lymphoma is a broad term encompassing a variety of cancers of the lymphatic system. There are today 263 companies plus partners developing 378 lymphoma drugs in 694 developmental projects in cancer. In addition, there are 3  |  read more...
USD 6,746
 

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