Organ and Tissue Transplantation


February 1, 2012
428 Pages - SKU: GJOB3828755
License type:
Table of Contents Related Reports
I. INTRODUCTION, METHODOLOGY &PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study
Tissue and Organ Transplantation
Bone Graft Transplantation
Product Definitions
Organ Transplantation
Heart Transplantation
Kidney Transplantation
Liver Transplantation
Pancreas Transplantation
Small Intestine Transplantation
Lungs
Tissue Transplantation
Corneal Transplantation
Blood Stem Cell Transplantation
Bone Marrow Transplantation
Heart Valves Transplantation
II. EXECUTIVE SUMMARY
1. MARKET OVERVIEW
A Quick Primer
Demand and Supply Imbalance
Measures to Address Organ Shortage
Cardiac Arrest Death Patients: The Untapped Potential Donors
Transplantation Expenses
2. MARKET TRENDS
Living Donor Organs on the Rise
Combined Organ Transplantation – Gaining Attention
Increasing Consent Rates – A Key Factor
Alliances to Play a Key Role
Graying Population and Chronic Diseases Surge Need for Transplants
Fetal Tissue for Bionic Devices – Assuming Importance
3. MAJOR ISSUES IMPACTING TRANSPLANTATION MARKET
Organ Rejection – A Major Barrier to Transplantation
Scarcity of Donor Organs – A Stumbling Block in Organ Transplantation
Other Issues for Organ Transplantation
Ethical Concerns in Transplants
Bioethical Issues Hinder Organ Donation Process
Lack of Requisite Expertise – Hindering Implantation Process
Corneal Transplantation in Developing Countries: Key Challenges
4. PRODUCT OVERVIEW
Organ and Tissue Transplantation
Organ Transplantation
Heart Transplantation
Heart Diseases and Disorders
Post Operative Complications and Consequences of Heart Transplants
Bleeding
Infection
Arrythymia
Heart Attack
Coronary Artery Disease
Respiratory Dysfunction
Renal Dysfunction
Graft Rejection and Dysfunction
Death
Kidney Transplantation
Kidney Disorders and Diseases
Donor Evaluation
Waiting List
Surgery/Post-Operation
Post-Operative Supervision and Issues
Liver Transplantation
Liver Disorders and Diseases
Pancreas Transplantation
Post Operative Complications and Consequences of Pancreas Transplants
Small Intestine Transplantation
Intestine Disorders and Diseases
Heart-and-Lung Transplantation
Lung Transplantation
Lung Diseases and Disorders
Lung Patients Survival Statistics
Tissue Transplantation
Types of Grafts
Autograft
Allograft / Homograft
Transplant Tolerance
Isograft
Xenograft
Corneal Transplantation
Penetrating Keratoplasty
Lamellar (Non-Penetrating) Keratoplasty
Aftercare
Risks Associated with Corneal Transplants
Transplantation Outcomes
Morbidity and Mortality Rates
Alternatives
Blood Stem Cells
Peripheral Blood Stem Cell Transplant
Umbilical Cord Blood Stem Cell Transplant
Bone Marrow and Hematopoietic Stem Cells
Bone and Tissue Transplantation
Bone Marrow Transplants
Stem Cell Therapy
Human Heart Valves
Atrioventricular Valves
Mitral Valve
Tricuspid Valve
Semilunar Valves
Aortic Valve
Pulmonic Valve
Pathology of Valves
Prosthetic Heart Valves
Prosthetic Mechanical Valve
Advantages
Disadvantages
Prosthetic Biologic Valve
Advantages
Disadvantages
Fetal Cells
Fetal Tissue for Transplantation
Storage Duration Time
Storage Time Period for Organs and Tissues
Cold Ischemia Time
Transplantation Immunology
Acute Cellular Rejection
Chronic Rejection
Post Transplant Observations
Types of Donors
Alive Donors
Related Donors
Good Samaritans
Rewarded/Forced Donors
Deceased Donors
Directed / Allocated
Organs and Tissues Transplanted by Type of Donor
Organ/Tissue Donation and Eligibility Criteria
Factors Considered for Matching Recipients to Donor Organs
Testing
Blood Typing
Tissue Typing
Histocompatibility – A Major Barrier for Organ Transplantation
Transplantation – Safety Requirements
Waiting List
Active Waiting List Patients
Inactive Waiting List Patients
History
Major Milestones in Organ Transplantation
5. ARTIFICIAL ORGANS
Artificial Organs Revolutionize Medical Technology Industry
Artificial Organs
Categorization of Artificial Organs
External Artificial Organs
Internal or Implantable Artificial Devices
Artificial Heart
Total Artificial Heart (TAH)
Ventricle Assist Device (VAD)
Right Ventricular Assist Systems (RVAS)
Left Ventricular Assist Systems (LVAS)
Various Ventricle Assist Devices Approved in the Recent Past
Artificial Kidney (Dialyzer)
Limitations of Artificial Kidney
Artificial Liver
Various Liver Assist Devices
Categorization of Liver Devices
Mechanical Systems
Bio-Artificial Systems
Artificial Pancreas
Artificial Lungs (Oxygenator)
Types of Artificial Lung
Artificial Cornea
Keratoprostheses
Tissue Engineered Corneas
Artificial Skin/Skin Replacement Products
AlloDerm Regenerative Tissue Matrix
Apligraf
Cymetra Micronized AlloDerm Tissue
Dermagraft
Epicel
Integra Products
OrCel
TransCyte
Core Competitive Factors
Market Outlook for Artificial Organs
6. PRESERVATION SOLUTIONS & IMMUNOSUPPRESSANT DRUGS
Organ Preservation Solutions
Celsior Solution
Collins Solution
Euro Collins Solution
Custodiol® HTK Solution
Hypothermosol
ViaSpan
Immunosuppressant Drugs
Antibody Products for Treatment of Organ Transplant Rejection
Antithymocyte Globulin
ATGAM
Campath/MabCampath
Thymoglobulin
Therapeutic Antibody Products
Antiproliferative Agents
Azathioprine
CellCept
Certican
Myfortic
Calcineurin Inhibitors
Cyclosporine
Gengraf
Neoral
Pulminiq
Tacrolimus
Prograf
TOR Inhibitors
Side Effects of Immunosuppression Therapy
Select Immunosuppressant Drug Players
Astellas Pharma US, Inc. (USA)
F.Hoffmann-La Roche Ltd. (Switzerland)
Novartis AG (Switzerland)
Wyeth (USA)
7. REGULATORY ENVIRONMENT
Transplant Center
Organ Procurement Organization (OPO)
Health Resources and Services Administration (HRSA)
Division of Transplantation (DoT)
United Network for Organ Sharing (UNOS)
Organ Procurement and Transplantation Network (OPTN)
University Renal Research and Education Association (URREA)
Scientific Registry of Transplant Recipients (SRTR)
Funding Sources
Patient Education and Advocacy Organizations
Legal Framework for Transplantation
Legislation Covering Organ Transplant
Organ Transplantation and Ethics
Regulations Governing Artificial Organs
8. PRODUCT DEVELOPMENT/INNOVATIONS
Dr. Reddy's to Launch Tacrolimus Capsules in US
ApaTech® Unveils Actifuse® MIS Bone Graft Delivery System
DePuy Spine Introduces HEALOS® Fx Injectable Bone Graft Replacement
Watson Laboratories Receives FDA Approval for Tacrolimus 5 mg
RTI Biologics Introduces Osteochondral Allograft in San Francisco
Pluristem Develops New Cell Graft for Cancer Patients
CryoLife Develops Cryopreserved Orthopaedic Tissues Implants
Japanese Innovators Develop New Prognostic Scoring Model for Liver Transplants
EUREKA project E! 2674 MIDAS Develops New Test to Improve Graft Survival
9. RECENT INDUSTRY ACTIVITY
Sanofi-Aventis Snaps Up Genzyme Corp.
International Stem Cell Inks Partnership Deal with Sankara Nethralaya
BGS Global Hospitals Inaugurates New Multi-Organ Transplants Center in India
Vietnamese Ministry of Health to Establish Organ Transplant Coordination Center
Novartis Secures US FDA Approval for Zortress Oral Tablets
Humacyte Enters into Strategic Alliance with Xcellerex
Osteotech Signs Agreement with Community Tissue Services
Tissue Banks International Enters into a Partnership with Northwest Tissue Services
Roche Secures FDA Approval for Valcyte
Astellas Pharma Secures FDA Clearance for Prograf and MMF Drug Combination
Astellas Pharma Receives Additional Approval for Prograf
Novadaq® Obtains US FDA Approval for SPY® System
Teleflex Acquires Arrow International
St. Jude Medical’s Heart Valve Obtains US FDA Approval
Zimmer and Tutogen Expand Distribution Partnership
10. CORPORATE ACTIVITY IN THE RECENT PAST- A PERSPECTIVE BUILDER
Leman Cardiovascular Acquires Hancock Jaffe Laboratories
Nabi Acquires Commercialization Rights of ATG-Fresenius S for North America
Cytopia and Novartis Ink Research Collaboration and Global License Agreement
ZLB Behring Inks Agreement with MedImmune
Japanese Team To Perform Liver Transplants in Hyderabad
Nabi Bags Approval for HB Intravenous in Liver Transplant Patients
Schering-Plough Announces PROTECT study Initiation
Allegheny General Hospital To Establish Adult Liver Transplantation Center in Oakland
Global Hospitals to Setup an Organ Transplant Center in Kolkata
GCC to Establish Organ Transplant Center
Delhi-Based Hospital Offers Help in Setting Up of Liver Transplant Center in Lahore
Kaiser To Shut Down Kidney Transplant Center
Abiomed Obtains FDA Approval for Selling Artificial Hearts
Astellas Bags FDA Approval to Use Prograf in Heart Transplant Patients
New York State Department of Health Approves Program for Kidney Transplant for Queen’s Community
National Heart Institute Conducts First Double Lung Transplant in Malaysia
The Netherlands Obtains Orphan Drug Designations for Treatment of DGF
Papworth Transplants First Beating Human Heart in the UK
Enzon to Return ATG-Fresenius S Rights to Fresenius Biotech
Schering-Plough to Conduct ‘PROTECT’ Study
Community Tissue Services Selects NOVA 2200 Supercritical Carbon Dioxide Sterilization Technology
CryoLife Inks Agreement with The Magdi Yacoub Institute to Enhance Xenografts in Human Transplantation
ReGen Inks Exclusive Marketing Deals with Polymedic and Xmedica
University of California-Irvine Announces Closure of Liver-Transplantation Program
Swedish Health Services Bags Approval for Liver Transplant Program
New Organ Transplant Research Center in South Korea
Child Lung Transplant Unit to be opened in Melbourne Hospital
Narayana Hrudayalaya Health City Establishes Exclusive Organ Transplant Hospital
Liver Transplant Facility in Delhi Region
First Liver Transplant Research Institute in China
PIMS to establish Liver Transplant Unit
Liver Transplant Programme in Pakistan
Isotechnika Gains FDA Approval
FDA Offers Approval for Brain Stem Cell Transplant Trial
Methodist Specialty and Transplant Hospital Gains Approval to Execute Liver Transplants
Cubist Pharma Enters into Licensing Agreement with XTL Biopharmaceuticals
Jackson Memorial Receives Approval from the U.S. Centers for Medicare and Medicaid Services
Royal Perth Hospital to Open Lung Transplant Unit in Perth
Mater Hospital Opens Lung Transplant Unit in Dublin
Genzyme Makes a Synergistic Purchase of Ilex Oncology
NIAID Sets Up Clinical Consortium to Enhance Organ Transplants Success
Chiron files NDA for Pulminiq Inhalation Solution
Roche Acquires
Antagonist
Genzyme Completes Acquisition of SangStat
11. FOCUS ON SELECT GLOBAL PLAYERS
Abiomed, Inc. (USA)
CryoLife, Inc.(USA)
Exactech, Inc. (USA)
Fresenius Medical Care AG & Co. KGaA (Germany)
Gambro AB (Sweden)
Genzyme Corporation (USA)
Jarvik Heart, Inc. (USA)
LifeCell Corporation (USA)
Medtronic, Inc. (USA)
MicroMed Cardiovascular, Inc. (USA)
Organogenesis, Inc. (USA)
SynCardia Systems (USA)
Terumo Corporation (Japan)
Teleflex Inc. (USA)
Thoratec Corporation (USA)
WorldHeart Corporation (USA)
12. GLOBAL MARKET PERSPECTIVE
Table 1: World Recent Past, Current & Future MarketAnalysis for Organ Transplantation by GeographicRegion – US, Canada, Europe, Asia (includingJapan), Latin America and Rest of WorldIndependently Analyzed by Number of Proceduresfor Years 2009 through 2017 (includescorresponding Graph/Chart)
Table 2: World Historic Review for Organ Transplantationby Geographic Region – US, Canada, Europe, Asia-Pacific (including Japan), Latin America and Rest of World Independently Analyzed by Number of Proceduresfor Years 2003 through 2008 (includescorresponding Graph/Chart)
Table 3: World 15-Year Perspective for OrganTransplantation by Geographic Region –Percentage Breakdown of Number of Procedures forUS, Canada, Europe, Asia-Pacific (including Japan),Latin America and Rest of World Markets for Years2003, 2011 & 2017(includes correspondingGraph/Chart)
Table 4: World Recent Past, Current & Future MarketAnalysis for Heart Transplantation by GeographicRegion – US, Canada, Europe, Asia-Pacific(including Japan), Latin America and Rest of World Independently Analyzed by Number of Proceduresfor Years 2009 through 2017 (includes correspondingGraph/Chart)
Table 5: World Historic Review for Heart Transplantationby Geographic Region – US, Canada, Europe, Asia-Pacific (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures forYears 2003 through 2008 (includes correspondingGraph/Chart)
Table 6: World 15-Year Perspective for Heart Transplantationby Geographic Region – Percentage Breakdown ofNumber of Procedures for US, Canada, Europe,Asia-Pacific (including Japan), Latin America andRest of World Markets for Years 2003,2011 & 2017 (includes corresponding Graph/Chart)
Table 7: World Recent Past, Current & Future MarketAnalysis for Kidney Transplantation by GeographicRegion – US, Canada, Europe, Asia-Pacific(including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures forYears 2009 through 2017 (includes correspondingGraph/Chart)
Table 8: World Historic Review for Kidney Transplantationby Geographic Region – US, Canada, Europe, Asia-Pacific (including Japan), Latin America and Rest of WorldIndependently Analyzed by Number of Proceduresfor Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 9: World 15-Year Perspective for Kidney Transplantationby Geographic Region – Percentage Breakdown ofNumber of Procedures for US, Canada, Europe,Asia-Pacific (including Japan), Latin America andRest of World Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
Table 10: World Recent Past, Current & Future MarketAnalysis for Liver Transplantation by Geographic Region –US, Canada, Europe, Asia-Pacific (including Japan),Latin America and Rest of World Independently Analyzedby Number of Procedures for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 11: World Historic Review for Liver Transplantationby Geographic Region – US, Canada, Europe, Asia-Pacific(including Japan), Latin America and Rest of WorldIndependently Analyzed by Number of Procedures forYears 2003 through 2008 (includes correspondingGraph/Chart)
Table 12: World 15-Year Perspective for LiverTransplantation by Geographic Region – PercentageBreakdown of Number of Procedures for US, Canada,Europe, Asia-Pacific (including Japan), Latin Americaand Rest of World Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
Table 13: World Recent Past, Current & Future MarketAnalysis for Pancreas Transplantation by GeographicRegion – US, Canada, Europe, Asia-Pacific (including Japan),Latin America and Rest of World Independently Analyzedby Number of Procedures for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 14: World Historic Review for PancreasTransplantation by Geographic Region – US, Canada,Europe, Asia-Pacific (including Japan), Latin Americaand Rest of World Independently Analyzed by Numberof Procedures for Years 2003 through 2008 (includescorresponding Graph/Chart)
Table 15: World 15-Year Perspective for Pancreas Transplantation by Geographic Region – PercentageBreakdown of Number of Procedures for US, Canada,Europe, Asia-Pacific (including Japan), Latin America andRest of World Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
Table 16: World Recent Past, Current & Future MarketAnalysis for Lung Transplantation by Geographic Region –US, Canada, Europe, Asia-Pacific (including Japan),Latin America and Rest of World Independently Analyzedby Number of Procedures for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 17: World Historic Review for Lung Transplantationby Geographic Region – US, Canada, Europe, Asia-Pacific (including Japan), Latin America and Rest of WorldIndependently Analyzed by Number of Procedures for Years2003 through 2008 (includes corresponding Graph/Chart)
Table 18: World 15-Year Perspective for LungTransplantation by Geographic Region – PercentageBreakdown of Number of Procedures for US, Canada,Europe, Asia-Pacific (including Japan), Latin Americaand Rest of World Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
Table 19: World Recent Past, Current & Future MarketAnalysis for Corneal Transplantation by GeographicRegion – US, Canada, Europe, Asia-Pacific (including Japan), Latin America and Rest of World Independently Analyzed by Number of Procedures for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 20: World Historic Review for CornealTransplantation by Geographic Region – US, Canada,Europe, Asia-Pacific (including Japan), Latin Americaand Rest of World Independently Analyzed by Numberof Procedures for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 21: World 15-Year Perspective for CornealTransplantation by Geographic Region – PercentageBreakdown of Number of Procedures for US, Canada,Europe, Asia-Pacific (including Japan), Latin Americaand Rest of World Markets for Years 2003, 2011 &2017 (includes corresponding Graph/Chart)
III. MARKET
1. THE UNITED STATES
A. Market Analysis
A Few Organ Transplant Facts and Figures in the US
Sources of Donor Organs
Table 22: US Kidney Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 23: US Liver Donations by Donor Type -Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 24: US Heart Donations by Cadaveric DonorType for Years 2003 through 2008 (includescorresponding Graph/Chart)
Table 25: US Lung Donations by Donor Type -Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 26: US Pancreas Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 27: US Intestine Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart)
Key Market Trends
Innovative Means of Organ Procurement to Increase Organ Donations
A New Technique to Enhance and Extend Kidney Transplants
California Stands Up Against Insurance on HIV Patients’ Transplantation
Awareness Programs to Address Shortage of Minority Donors
Organs and Tissues on A Recovery Spree
Unexamined Human Tissue Transplants – A Major Threat
Defective Medical Implants – A Health Hazard
Eye Infections from Usage of MoistureLoc Leads to Corneal Transplants
Incidence of Organ Transplants
Table 28: Incidence of Organ Transplant per 1 MillionPopulation in the US by Type - Kidney, Liver,Heart, Lung, Pancreas, Intestine, and Heart-Lung Transplants, for the Year 2003 through 2008(includes corresponding Graph/Chart)
Table 29: Incidence of Organ Transplants (Kidney,Liver, Heart, Lung, Pancreas, Intestine, and Heart-Lung) per 1 Million Population in the US by RecipientRace (White, African American, Asian, Hispanic,and Other) for 2008 (includes correspondingGraph/Chart)
Table 30: Incidence of Organ Transplants (Kidney,Liver, Heart, Lung, Pancreas, Intestine, andHeart-Lung) per 1 Million Population in the USby Recipient Gender (Male, and Female) for2008 (includes corresponding Graph/Chart)
Table 31: Incidence of Organ Transplants (Kidney,Liver, Heart, Lung, Pancreas, Intestine, andHeart-Lung) per 1 Million Population in the US by Recipient Age (65+ Years, 50-64 Years, 35-49 Years,18-34 Years, 11-17 Years, 6-10 Years, 1-5 Years,<1 Year) for 2008 (includes correspondingGraph/Chart)
Heart Transplantation
Table 32: Heart Transplant Life Expectancyin the US (2009): As of 2009 (includescorresponding Graph/Chart)
Lung Transplantation
Heart-Lung Transplantation
Waiting List
Table 33: Waiting List of Patients As of July 2010(includes corresponding Graph/Chart)
Table 34: Waiting List of Active and InactivePatients for the Year 2008 (includescorresponding Graph/Chart)
Waiting List for Heart Transplants
Table 35: Waiting List of Active Patients for Heartfor Years 2000 to 2008 (includes corresponding Graph/Chart)
Categorized by Diseases
Categorized by Age
Categorized by Race
Death Rates on the Waiting Lists
Kidney Transplantation Waiting List
Categorized by Age
Categorized by Race
Waiting List for Liver Transplants
Categorized by Age
Categorized by Race
Categorized by Gender
Categorized by Diseases
Categorized by Re-Transplant Necessity
Pancreas Transplant Waiting List
Simultaneous Pancreas Kidney Transplantation Waiting List
Waiting List for Lung Transplants
Categorized by Age
Categorized by Primary Diagnoses
Categorized by Gender and Ethnic Makeup
Waiting List for Intestine Transplants
Death Rates on Waiting List
Patient Survival Rate
Table 36: Unadjusted Patient Survival Rate (*) byOrgan Type for 1-Year and 5-Years (includes corresponding Graph/Chart)
Multi-Organ Transplant Gaining Momentum
Table 37: Multi-Organ Transplants in the US:2005-2008 (includes correspondingGraph/Chart)
Immunosuppression Therapy
Immunosuppression Therapy for Heart Transplant Recipients
Table 38: Usage Rates of Major Immunosuppressantsat Discharge by Organ Type for the Year 2008(includes corresponding Graph/Chart)
Immunosuppression Therapy for Kidney Transplant Recipients
Immunosuppression Therapy for Pancreas Transplants
Immunosuppression Therapy for Lung Transplant Recipients
Table 39: Usage Rates of Induction Drugs ForLung Transplant Recipients in 2008(includes corresponding Graph/Chart)
Table 40: US Recent Past, Current & FutureMarket Analysis for Immunosuppressive DrugTherapy Following Bone Marrow Transplantationby Category – For GVHD and Maintenance Independently Analyzed with Annual Sales Figuresin US$ Million for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 41: US Historic Review for ImmunosuppressiveDrug Therapy Following Bone MarrowTransplantation by Category – For GVHDand Maintenance Independently Analyzed withAnnual Sales Figures in US$ Million forYears 2003 through 2008 (includescorresponding Graph/Chart)
Table 42: US 15-Year Perspective for Immunosuppressive Drug Therapy FollowingBone Marrow Transplantation by Category –Percentage Breakdown of Dollar Sales ForGVHD and Maintenance Independently Analyzedwith Annual Sales Figures in US$ Millionfor Years 2003, 2011, and 2017
Immunosuppression Therapy, Following Blood Stem Cell Transplantation
Table 43: US Recent Past, Current & Future Market Analysis for Immunosuppressive Drug Therapy Following Blood Stem Cell Transplantation byCategory – For GVHD and MaintenanceIndependently Analyzed with Annual SalesFigures in US$ Million for Years 2009through 2017 (includes correspondingGraph/Chart)
Table 44: US Historic Review for ImmunosuppressiveDrug Therapy Following Blood Stem Cell Transplantation by Category – For GVHD and Maintenance Independently Analyzed withAnnual Sales Figures in US$ Million forYears 2003 through 2008 (includescorresponding Graph/Chart)
Table 45: US 15-Year Perspective for Immunosuppressive Drug Therapy FollowingBlood Stem Cell Transplantation by Category – Percentage Breakdown of Dollar Sales ForGVHD and Maintenance Independently Analyzedwith Annual Sales Figures in US$ Million forYears 2003, 2011, and 2017
The United Network for Organ Sharing
The American Association of Tissue Banks (AATB)
Accredited Banks from Select US States
Eye Banks from Select US States
Number of Transplant Center Programs
Table 46: Number of Transplant Center Programsfor the Years 1990, 1997 and 2000 (includescorresponding Graph/Chart)
Table 47: Average Number of Transplants PerProgram for the Years 1990, 1997 and 2000(includes corresponding Graph/Chart)
B. Market Analytics
Table 48: US Recent Past, Current & Future MarketAnalysis for Organ Transplantation by Organ Type –Heart, Kidney, Liver, Pancreas, Lung and Intestine Independently Analyzed with Annual Sales Figuresin US$ Million for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 49: US Historic Review for Organ Transplantationby Organ Type – Heart, Kidney, Liver, Pancreas, Lungand Intestine Independently Analyzed with AnnualSales Figures in US$ Million Years 2003 through2008 (includes corresponding Graph/Chart)
Table 50: US 15-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Dollar Sales for Heart, Kidney, Liver, Pancreas, Lung and Intestine Markets for Years 2003, 2011 & 2017(includescorresponding Graph/Chart)
Table 51: US Recent Past, Current & Future MarketAnalysis for Tissue Transplantation by Tissue Type –Cornea, Heart Valves and Skin Grafts Independently Analyzed with Annual Sales Figures in US$ Millionfor Years 2009 through 2017 (includescorresponding Graph/Chart)
Table 52: US Historic Review for Tissue Transplantationby Tissue Type – Cornea, Heart Valves and Skin Grafts Independently Analyzed with Annual Sales Figuresin US$ Million for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 53: US 15-Year Perspective for Tissue Transplantation by Tissue Type – Percentage Breakdown of Dollar Sales for Cornea, Heart Valves and Skin Grafts Markets forYears 2003, 2011 & 2017 (includes corresponding Graph/Chart)
By Number of Procedures
Table 54: US Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas, Lung and Intestine Independently Analyzed by Number of Procedures for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 55: US Historic Review for Organ Transplantationby Organ Type – Heart, Kidney, Liver, Pancreas, Lungand Intestine Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 56: US 15-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas, Lung and Intestine Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
Table 57: US Recent Past, Current & Future MarketAnalysis for Tissue Transplantation by Tissue Type –Cornea, Heart Valves, Skin Grafts, Vascular Grafts,Bone Marrow and Bone Grafts Independently Analyzed by Number of Procedures for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 58: US Historic Review for Tissue Transplantationby Tissue Type – Cornea, Heart Valves, Skin Grafts,Vascular Grafts, Bone Marrow and Bone Grafts Independently Analyzed by Number of Proceduresfor Years 2003 through 2008 (includescorresponding Graph/Chart)
Table 59: US 15-Year Perspective for TissueTransplantation by Tissue Type – Percentage Breakdownof Number of Procedures for Cornea, Heart Valves,Skin Grafts, Vascular Grafts, Bone Marrow andBone Grafts Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
Table 60: US Recent Past, Current & Future MarketAnalysis for Bone Graft Transplantation by Graft Type – Autologous Graft, Allograft and Other Materials Independently Analyzed by Number of Proceduresfor Years 2009 through 2017 (includescorresponding Graph/Chart)
Table 61: US Historic Review for Bone GraftTransplantation by Graft Type – Autologous Graft,Allograft and Other Materials Independently Analyzedby Number of Procedures for Years 2003 through2008 (includes corresponding Graph/Chart)
Table 62: US 15-Year Perspective for Bone Graft Transplantation by Graft Type – PercentageBreakdown of Number of Procedures forAutologous Graft, Allograft and Other MaterialsMarkets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
Table 63: US Recent Past, Current & Future MarketAnalysis for Bone Graft Transplantation byApplication – General Orthopedics, Spinal Fusionsand Cranio/Maxillofacial Independently Analyzed byNumber of Procedures for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 64: US Historic Review for Bone Graft Transplantation by Application – General Orthopedics, Spinal Fusions and Cranio/Maxillofacial Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 65: US 15-Year Perspective for Bone Graft Transplantation by Application – Percentage Breakdown of Number of Procedures for General Orthopedics, Spinal Fusions and Cranio/Maxillofacial Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
2. CANADA
A. Market Analysis
Canadians More Receptive to Organ Transplants
Waiting List
Table 66: Canadian Patients (Active and Inactive)on Waiting List by Organ Type for 2009 and 1H 2010 (*)(includes corresponding Graph/Chart)
Organ Donation
Table 67: Canadian Organ Donations by Donor Type - Cadaveric and Living for Years 2003 through 2008 (includes corresponding Graph/Chart)
Success Rate of Organ Transplants
Table 68: Success Rate of Organ Transplants After 1-Year (includes corresponding Graph/Chart)
B. Market Analytics
Table 69: Canadian Recent Past, Current & FutureMarket Analysis for Organ Transplantation byOrgan Type – Heart, Kidney, Liver, Pancreas andLung Independently Analyzed by Number ofProcedures for Years 2009 through 2017(includes corresponding Graph/Chart)
Table 70: Canadian Historic Review for Organ Transplantation by Organ Type – Heart, Kidney,Liver, Pancreas and Lung Independently Analyzed byNumber of Procedures for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 71: Canadian 15-Year Perspective for Organ Transplantation by Organ Type – PercentageBreakdown of Number of Procedures for Heart,Kidney, Liver, Pancreas and Lung Markets forYears 2003, 2011 & 2017(includescorresponding Graph/Chart)
3. EUROPE
A. Market Analysis
Table 72: Number of Organ Transplants in SelectEuropean Countries by Organ: 2009 (includescorresponding Graph/Chart)
Table 73: Number of Deceased Organ Donorsin Select European Countries for 2008 & 2009(includes corresponding Graph/Chart)
Focus on Select Regions
The United Kingdom
UK Organ Transplantation System: An Overview
Organ Transplantation in the UK
Table 74: UK Organ Transplantationsfor the Years 2007 and 2008 (includescorresponding Graph/Chart)
Table 75: Waiting List (Active and Inactive) byOrgan in the UK for the Years 2007 and 2008 (includes corresponding Graph/Chart)
Corneal Transplantation in the UK
Bladder Transplantation: A Roaring Success
Spain
Organ Transplantation in Spain
France
Table 76: Organ Transplantations in Francefor the Years 2006 through 2008 (includescorresponding Graph/Chart)
Table 77: Waiting List (Active and Inactive) byOrgan in France for the Years 2006 through2008 (includes corresponding Graph/Chart)
Italy
Surge in Organ Transplants
Russia
Organ Transplantations Show a Downward Trend in Russia
Turkey
Akdeniz University – A World-Renowned Transplantation Center
B. Market Analytics
Table 78: European Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 79: European Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Numberof Procedures for Years 2003 through 2008 (includes corresponding Graph/Chart)
Table 80: European 15-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdown of Number of Procedures for Heart, Kidney, Liver, Pancreas and Lung Markets for Years 2003, 2011 & 2017(includes corresponding Graph/Chart)
4. ASIA-PACIFIC
A. Market Analysis
Focus on Select Regions
Australia
Key Facts on Organ and Tissue Transplantation in Australia
Australia Registers Highest Success Rate in Transplantation
Table 81: Organ Transplantation in Australia by Organ Type: 2008 (includes corresponding Graph/Chart)
Table 82: Organ Transplant Waiting List byOrgan Type: As of January 2010 (includes corresponding Graph/Chart)
Kidney Transplantation Snapshots
Organ Donor Register
China
Organ Transplantations in China: Year 2005 & 6 in Review
Transplantation Tourism in China
Low Transplant Success Rate Due to Unskilled Professionals
Cost Effective Transplant Procedures Lure Foreign Patients
Illegal Activities for Harvesting Organs in China
Regulations on Organ Transplantation
Regulations on Brain Death
India
Overview of Renal Transplantation
Transplantation Expenses in India
Indian Government to Amend Organ Transplantation Rules
Singapore
Awareness Programs to Increase Living Kidney Donations in Singapore
Taiwan
Taiwan Competes with the US in Kidney and Liver Transplant Survival Rates
B. Market Analytics
Table 83: Asia-Pacific Recent Past, Current & FutureMarket Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009 through 2017 (includes corresponding Graph/Chart)
Table 84: Asia-Pacific Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2003 through 2008 (includescorresponding Graph/Chart)
Table 85: Asia-Pacific 15-Year Perspective for OrganTransplantation by Organ Type – Percentage Breakdownof Number of Procedures for Heart, Kidney, Liver,Pancreas and Lung Markets for Years 2003, 2011 &2017 (includes corresponding Graph/Chart)
5. LATIN AMERICA
A. Market Analysis
Brazil – A Major Transplant Market
B. Market Analytics
Table 86: Latin American Recent Past, Current & Future Market Analysis for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Procedures for Years 2009through 2017 (includes corresponding Graph/Chart)
Table 87: Latin American Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Numberof Procedures for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 88: Latin American 15-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdownof Number of Procedures for Heart, Kidney, Liver,Pancreas and Lung Markets for Years 2003, 2011 &2017 (includes corresponding Graph/Chart)
6. REST OF WORLD
A. Market Analysis
Kuwait – A Rapidly Emerging ‘Third World’ Country in Organ Transplants
South Africa
Key Statistical Findings on Organ and Cornea Transplants
Table 89: Number of Organ and Cornea Transplantsin South Africa for Years 2005 through 2009(includes corresponding Graph/Chart)
Table 90: Number of Organ Transplants (Excluding Cornea) in South Africa by Organ for Years 2008 & 2009 (includes corresponding Graph/Chart)
Table 91: Number of Organ Transplants in Adult Patients in South Africa by Organ for yeas 2008 & 2009 (includes corresponding Graph/Chart)
Table 92: Number of Organ Transplants in Adolescent Patients in South Africa by Organ for Years 2008 & 2009 (includes corresponding Graph/Chart)
Table 93: Number of Organ Transplants (Excluding Cornea) in Pediatric Patients in South Africa byOrgan for Years 2008 & 2009 (includescorresponding Graph/Chart)
Table 94: Number of Heart Transplants in SouthAfrica for Years 2005 through 2009 (includes corresponding Graph/Chart)
Table 95: Number of Kidney Transplants inSouth Africa for Years 2005 through 2009(includes corresponding Graph/Chart)
Table 96: Number of Lung Transplants in SouthAfrica for Years 2005 through 2009 (includes corresponding Graph/Chart)
Table 97: Organ Transplants (Excluding Cornea)in South Africa by Region (2008 & 2009): Percentage Breakdown of Volume Procedures for Cape Town, Johannesburg, Durban, Pretoria and Bloemfontein (includes corresponding Graph/Chart)
Table 98: Cornea Transplants in South Africa byRegion (2008 & 2009): Percentage Breakdown of Volume Procedures for Johannesburg, Durban,Cape Town, Pretoria and Port Elizabeth(includes corresponding Graph/Chart)
B. Market Analytics
Table 99: Rest of World Recent Past, Current & Future Market Analysis for Organ Transplantation by OrganType – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Number of Proceduresfor Years 2009 through 2017 (includescorresponding Graph/Chart)
Table 100: Rest of World Historic Review for Organ Transplantation by Organ Type – Heart, Kidney, Liver, Pancreas and Lung Independently Analyzed by Numberof Procedures for Years 2003 through 2008(includes corresponding Graph/Chart)
Table 101: Rest of World 15-Year Perspective for Organ Transplantation by Organ Type – Percentage Breakdownof Number of Procedures for Heart, Kidney, Liver,Pancreas and Lung Markets for Years 2003, 2011 &2017 (includes corresponding Graph/Chart)
IV. COMPETITIVE LANDSCAPE
Total Companies Profiled: 75 (including Divisions/Subsidiaries - 88)Region/Country Players
The United States 58
Canada 2
Japan 10
Europe 16
France 1
Germany 6
The United Kingdom 2
Italy 3
Rest of Europe 4
Asia-Pacific (Excluding Japan) 1
Middle-East 1
 
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