Monoclonal Antibody Based Products


October 1, 2008
527 Pages - SKU: GJOB2073343
License type:
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study
Therapeutics
Cancer
Other Therapeutic Mabs
Diagnostics
II. EXECUTIVE SUMMERY
1. Industry Overview
World MAb-Based Products Market: A Profile
MAb Market - Set for Significant Growth
Therapeutic mAb Market - Principal Driving Force
Development of New MAbs on a Fast Track
Genomics Research Leads Way to New Monoclonal Antibodies
Bright Outlook for MAbs
Current and Future Analysis
Regional Perspective
Product Segment Perspective
Competitive Scenario
Intensifying Consolidation Activity
Table 1: Major Acquisitions of Antibody-Focused Companies (2005-2007)
Table 2: Leading Players in the Worldwide Monoclonal Antibody Therapy Market (2005): Percentage Breakdown of Sales for Genentech/Roche, J & J/Schering Plough, Abbott Laboratories, MedImmune, ImClone/BMS, and Eli Lilly (includes corresponding Graph/Chart)
Table 3: Leading Drugs in the Global Therapeutic Monoclonal Antibodies Market (2006): Percentage Breakdown of Dollar Sales for Remicade, Rituxan, Herceptin, Avastin, Humira, Erbitux, Synagis, Xolair and Others (includes corresponding Graph/Chart)
Table 4: Monoclonal Antibody Based Products Market (2004): Percentage Breakdown of Leading Manufacturers by Sales for Genentech, Johnson & Johnson, Roche, Abbott, MedImmune, Schering Plough, Eli Lilly, and Others (includes corresponding Graph/Chart)
Table 5: Monoclonal Antibody Based Products Market (2004): Percentage Breakdown of Leading Drugs by Sales for Remicade, Rituxan, Herceptin, Synagis, Humira, Avastin, ReoPro, Erbitux, Xolair, and Others (includes corresponding Graph/Chart)
Table 6: Leading Products in the Global Oncology Monoclonal Antibodies Market (2008E): Percentage Share Breakdown of Sales for Avastin, Herceptin, Rituxan, Erbitux, and Others (includes corresponding Graph/Chart)
Table 7: Leading Products in the Global Antibody-Based Anti-Inflammatory Market (2006): Percentage Share Breakdown of Revenues for Enbrel, Remicade, Humira, and Others (includes corresponding Graph/Chart)
Therapeutic Antibodies in the Market
Drug Developers Trying to Break the Shackles
Rituximab Vs. Epratuzumab
A Revolution Not too Far
Milestones in Development of MAbs
Focus on Unmet Medical Needs in the Emerging Markets
2. Industry Analysis
Evolution of Monoclonal Antibodies - A Historical Journey
Trends and Issues
Shift Towards Humanized and Fully Human Antibodies
Ageing Baby Boomers Spur MAbs Growth
Non-Existent Generic Competition Favors MAb Market
Partnerships and Collaborations Spark Increase in Profit Margins
Pharma Majors & CMOs Augment Investment in Mab Production
Rising Number of MAbs Under Clinical Trials
Select Clinical Trials for Monoclonal Antibodies
Major Monoclonal Antibodies in Phase III Trials Across the World
High Costs Impede MAbs Penetration
Opportunities in Technology Development
Advancements & Challenges in Antibody Production Processes
Increasing Demand for Protein A in Mab Manufacturing
FCA- A Major Cause for Discomfort in Mice
Innovations to Drive Growth in Anti-Ovarian Cancer Drugs Market
Rising Incidence of NHL to Drive Monoclonal Antibody Drug Market
3. Product Overview
Immune System: Natural Defenders
Human Antibodies
Antibodies Offer Natural Immunity
Induction of The Immune Process
Mechanism of Action
Polyclonal and Monoclonal Antibodies
Production of Monoclonal Antibodies
Traditional Methods
The Hybridoma Technology
Separation and Purification of Monoclonals
Factors Impacting Production of MAbs
Types of Monoclonal Antibodies
Table 8: Worldwide MAb Market by Product Type (2008): Percentage Share Breakdown for Chimeric, Humanized, Human and Murine (includes corresponding Graph/Chart)
Murine Monoclonal Antibodies
Humanized Antibodies/ CDR Grafted Antibodies
Murine Vs Human Monoclonal Antibodies
Chimeric Antibodies: Show Lesser Antigenicity
Fully Human Antibodies
Bispecific Antibodies
Certain Limitations Do Exist
Advantages of MAbs
Advantages and Limitations of MAb Technologies
4. Diagnostic Applications of Monoclonal Antibodies
Monoclonal Antibody Based Diagnostics
Immunodiagnostics
Monoclonals Used as Targeting Agents
Radio labeled Monoclonal Antibodies for Diagnostic Imaging
The Pros and Cons of MAb-Based Immunoconjugates
Cytogen: The First to Introduce A Monoclonal Antibody-based Cancer Agent
NeoProbe’s Radioimmunogzuided Surgery
Cancer
A Historical Overview
Initial Hiccups
Tumor Markers
5. Monoclonal Antibody-Based Therapeutics
Evolution of Therapeutic Antibody Products
Advantages of Therapeutic Monoclonal Antibodies
Current Scenario in Monoclonal Antibody Therapeutics Market
Table 9: Monoclonal Antibody Market by Therapy Area (2004 & 2010): Percentage Breakdown by Sales for Oncology, Arthritis, Immune & Inflammatory Disorders, Infectious Diseases, Cardiovascular, Respiratory, Ophthalmology, and CNS (includes corresponding Graph/Chart)
Cancer Therapeutics
Monoclonal Antibodies Offer Hope Against Cancer
Monoclonal Antibodies Approved For Cancer Treatment in the World
Monoclonal Antibody Cancer Therapies Under Development
Antibody Therapies for Cancer
Cancer: A Serious Issue and Plaguing Illness Worldwide
Breast Cancer: The Most Common Form of Cancer in American Women
Breast Cancer - Treatment Options
Monoclonal Antibodies Against NHL
Monoclonal Antibodies Against Ovarian Cancer
MAb Immunotherapy - Effective for Residual Ovarian Cancer
Melanoma
Immunologic Effector Functions
Colorectal Cancer: Rising Incidence
Panorex: The First Cancer Therapeutic in the Market
Myeloid Leukemia
6. Other Therapeutic Monoclonal Antibodies
Therapeutic Monoclonal Antibody Drugs and Applications
MAbs used in Clinical Field
Inflammation Therapeutics
Inflammation
Asthma: A Chronic Affliction
Autoimmune Diseases
What Goes Wrong
Intervention Better Than Prevention
Some Autoimmune Diseases
Multiple Sclerosis
Crohn’s Disease
Rheumatoid Arthritis
Organ Transplantation
Biology of Transplantation
Types of Transplants
Autografts
Syngeneic Transplants
Allografts
Xenografts
Follow-up Treatment
Products to Counter Rejection
OKT3: A Monoclonal Already in the Market
Infectious Diseases
Sepsis
A Rapid Process
Gram Negative Bacteria are the Causative Agents
A Retrospect
Monoclonal Antibodies and Septic Shock
HIV/AIDS
What is AIDS?
Global Statistics
HIV/AIDS Testing
Monoclonal Antibodies and HIV
Cardiovascular
Cardiovascular Diseases are Fatal
Treatment Options
Causes of Cardiovascular Diseases
ReoPro
7. Regulation Impacting The Industry
Regulations in the U.S
Approval: A Laborious Process
Clinical Trials
Orphan Drug Status
8. Research and Development Activities
Rituxan and Herceptin from Genentech
FuCell hybridomas
Test-tube MAbs/ Phase Display Library
Rituxan for Cancer Treatment
GenMAb Develops Fully Human Antibodies
Protein Design Labs Licenses Trioma
Protein Design Labs’ Innovative Technology
9. Product Launches and Developments
Amgen Introduces Vectibix
Trevigen Introduces Mouse Monoclonal Antibody
UCB Receives FDA Approval for Cimzia®
GSK’s Tykerb Receives FDA Approval
Dr. Reddy’s Introduces Reditux™
Morphotek Receives Orphan Drug Status for MORAb - 009 mAb
Biocon Introduces BIOMab Monoclonal Antibody
Biotest AG and AERES Biomedical Develop BT- 062
Genentech Launches Avastin
Biotest Unveils Intratect®
Genentech Introduces Xolair
Genentech Unveils Raptiva
Corixa Presents BEXXAR
IGEN Launches Monoclonal Antibody Therapies
MAb Against Pseudomonas Aeruginosa
Wyeth Introduces Mylotarg
10. Recent Industry Activity
EUSA Pharma to Take Over Cytogen
AVANIR Inks a Definitive Agreement to Divest Anthrax Antibodies
Access Pharmaceuticals Acquires Somanta Pharmaceuticals
Daiichi Sankyo to Take Over U3 Pharma
IMUC Completes Molecular Antibody Technology Acquisition
Callisto Merger Corporation Merges with Celldex Therapeutics
Genmab Enters into Antibody Research Collaboration with Pepscan
BTI Enters into an Agreement with Raven
Arana and Kyowa Hakko Sign Agreement to Jointly Develop ART 104
Eusa Sells Antibody Research Business
CG Therapeutics and UoW Agree for Joint Monoclonal Antibody Program
Raven and CMC ICOS Collaborate to Advance RAV18
SDI to Develop mAbs for SAIC-F and NCI
HGS Reacquires Rights for TRAIL Receptor Antibodies
CAT Grants Exclusive Worldwide License of CAT-213 to iCo
Morphotek and HMI in Licensing Agreement
Amgen Enters into Licensing Agreement with Kyowa Hakko
Dyax and Sanofi-Aventis Sign Agreements
HGS Enters into Antibody Collaboration Agreement with Xencor
CSL Limited Inks a Collaboration Agreement with Celltrion
Eisai Acquires Morphotek
Astellas US Holding Takes Over Agensys
Astrazeneca Creates New Integrated Business Unit - Medimmune
Genentech Acquires Tanox
Biotest Acquires Assets of Nabi Biologics
CMC Acquires ICOS Biologics Operation
Roche Takes Over THP
GTC and LFB Commence CD20 Monoclonal Antibody Development
Regeneron Grants a Non-Exclusive License to AstraZeneca
OncoMed Enters into Monoclonal Antibody Deal with GSK
BioArctic and Eisai Announce Licensing Agreement
MediGene Collaborates with Celltrion
Amgen Inks Collaboration and License Pact with Daiichi Sankyo
CMC Biopharmaceuticals Inks Agreement with Morphotek
CMC Biopharmaceuticals Inks Agreement with Biotest
Eli Lilly Collaborates with MacroGenics
Genentech Inks Global Licensing Agreement with Seattle Genetics
VaxGen to Merge with Raven Biotechnologies
Abeome Enters into Distribution Agreement with Millipore
Compugen Forays into Monoclonal Antibody Business
MilleGen and LFB Enter into Partnership Agreement
Favrille Acquires Diversa’s Anti-CD20 Monoclonal Antibodies
Kirin Inks Licensing Agreement with Astellas Pharma
Viropro in Partnership with NRC-BRI
Merck Acquires Abmaxis
Micromet Merges with CancerVax
Tanabe & Janssen Team Up to Develop Anti-TNF Alpha Monoclonal Antibody
Intercell Enters into Strategic Alliance with Kirin
Xencor Extends R&D Collaboration with Roche
MedImmune Inks Licensing Agreement with Japan Tobacco
Immunomedics Enters into an Agreement with UCB for Epratuzumab
Akorn and Serum Institute Enter into Development and Distribution Agreement
FDA Clears IND for CYT-500 Monoclonal Antibody from Cytogen
LSP Acquires Global License for Monoclonal Antibodies from Ludwig Institute
Seattle Genetics in Agreement with Laureate to Manufacture Monoclonal Antibody Drug
Candidates
EU Grants Orphan Drug Designation to GPC’s Anticancer Monoclonal Antibody
Laureate Collaborates with Bradmer on Neuradiab Monoclonal Antibody for Cancer
Treatment
Amgen Takes Over Abgenix
Celera and Medarex in Strategic Alliance for Developing Human Monoclonal Antibody
Therapeutics
UCB Collaborates with Immunomedics
Crucell Collaborates with DSM for Monoclonal Antibody Licensing Business
Roche Licenses Rabbit Monoclonal Antibody Technology from Epitomics
BioGenex Receives FDA Pre-Market Approval for InSite™ Monoclonal Antibody
Upstate Bags Marketing Rights for Anti-ZAP-70 Monoclonal Antibody
XOMA Bags NIAID Contract to Develop Anti-Botulinum Neurotoxin Monoclonal
Antibodies
HGS Bags Two-Phase Contract for ABthrax™ Mab from the US Government
Medarex and PharmAthene Receive Funding for Development of Valortim™
UCB Collaborates with Millenium
MorphoSys Acquires Two Antibody Technology Companies
Tanabe Seiyaku and Remicade Sign Addendum
Abgenix Receives Royalty from Human Genome
Amgen Acquires Tularik
Sunesis Pharmaceuticals Collaborates with Biogen Idec
H3 Pharma Inc. Enters into a Manufacturing Agreement with DSM Biologics
EMBL and Abnova Inks Collaboration Agreement
AstraZeneca and CAT in Five-Year Strategic Alliance for Monoclonal Antibody
Research
UCB Acquires Celltech
ImmunoGen Signs Licensing Agreement with Biogen
Lonza Inks MAbs Manufacturing and Supply Agreement with NovImmune
Avanir and Peregrine Sign License Agreement
BioVest Concludes Agreement with Bioventix
Roche to Set Up Two Manufacturing Facilities in Switzerland
XTL Biopharm Bags European patent for Human Monoclonal Anti Body
MBL and Medarex Bags FDA approval for CDA-1 Phase I Trials
Health Canada Approves HUMIRA
11. Industry Activity in the Recent Past (2000-2003)
CAT Signs Licensing Agreement with Micromet
CAT Enters into Agreement with Genzyme
Medarex and Avlon Enter into Agreement
Micromet, Enzon and CAT Sign Cross-License Agreement
Xerion and CAT Enter into Agreement
Genetastix and Nissho Enter into Agreement
InNexus and Corixa Enter into Agreement
Abbott Collaborates with LigoCyte
CAT Acquires Drug Royalty Corporation
CAT and Amrad Join Hands for Research
IDEC's Receives FDA Approval for Zevalin
Medarex Enters into Research Alliance with Seattle Genetics
Dow, Epicyte and Centocor Join Forces to Develop Monoclonal Antibody
Eos, Medarex and Biosite in Alliance for Cancer Treatment
Imgenex forms Alliance with GMO
CAT and Elan Enter into Strategic Alliance
Bioinvent International Enters into Agreement with Novo Nordisk for Drug Discovery
Research
Epicyte and Dow Chemical Enter into Agreement
Rockland Announces the Completion of Laboratory Expansion
Roche’s MAbThera Receives Approval in Japan
Aviva Launches Manufacturing and Marketing Operations
ICOS and Seattle Enters into Joint Development and Manufacturing Agreement
Medarex and Corixa Team-up to Develop Human Monoclonal Antibodies
Taisho Enters into Research Alliance with IDEC
PDL Signs Agreement with InterMune
ProMetic Signs Agreement with Integrated Protein
Medarex Signs Agreement with ZynloGenetics
CAT Joins Hands with GD. Searle
Medarex and MedImmune Enter into Antibody Research Agreement
Lonza Signs Agreement with ImClone Systems
MedImmune and Alkermes Enter into Agreement
GTC and Abgenix Enter into Production Agreement
Genzyme Transgenics Expands Agreement with Centocor
PDL and InterMune Enter into an Agreement
12. Focus on Select Global Players
Amgen, Inc. (US)
BD Biosciences (US)
Biogen Idec Inc (US)
Biotest AG (Germany)
CMC ICOS Biologics, Inc
Dendreon Corporation (US)
Elan Corporations Plc (Ireland)
Eli Lilly and Company (US)
Genentech, Inc. (USA)
Human Genome Sciences, Inc. (US)
Immunomedics (US)
Johnson & Johnson (US)
Centocor (US)
Ortho Biotech Products, L.P. (US)
Medarex, Inc. (US)
MedImmune, Inc. (US)
PDL BioPharma (US)
Schering-Plough Corporation (US)
Strategic Diagnostics Inc (US)
UCB Group (Belgium)
Wyeth Pharmaceuticals (US)
13. Global Market Perspective
Table 10: World Recent Past, Current & Future Market Analysis for Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 11: World Long-term Projections for Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 12: World 10-Year Perspective for Monoclonal Antibody Based Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)
Table 13: World Recent Past, Current & Future Market Analysis for Therapeutic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 14: World Long-term Projections for Therapeutic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 15: World 10-Year Perspective for Monoclonal Antibody Based Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)
Table 16: World Long-term Projections for Therapeutic Monoclonal Antibody Based Products by Segment - Cancer and Other Therapeutics Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 17: World Long-term Projections for Therapeutic Monoclonal Antibody Based Products by Segment - Cancer and Other Therapeutics Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 18: World 10-Year Perspective for Therapeutic Monoclonal Antibody Based Products by Segments - Percentage Breakdown of Dollar Sales for Cancer and Other Therapeutics Markets for Years 2003, 2008 & 2012
Table 19: World Recent Past, Current & Future Market Analysis for Cancer Therapeutic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 20: World Long-term Projections for Cancer Therapeutic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 21: World 10-Year Perspective for Cancer Therapeutic Monoclonal Antibody Based Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)
Table 22: World Recent Past, Current & Future Market Analysis for Other Therapeutic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 23: World Long-term Projections for Other (*) Therapeutic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 24: World 10-Year Perspective for Other Therapeutic Monoclonal Antibody Based Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)
Table 25: World Recent Past, Current & Future Market Analysis for Diagnostic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 26: World Long-term Projections for Diagnostic Monoclonal Antibody Based Products by Geographic Region - US, Canada, Japan, Europe, and Rest of World Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 27: World 10-Year Perspective for Diagnostic Monoclonal Antibody Based Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe and Rest of World Markets for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)
III. MARKET
1. The Untied States
A. Market Analysis
Global Hub of MAbs
Approved Therapeutic Antibodies in the US (As of 2007)
Therapeutic Monoclonal Antibodies Market - An Overview
New Heights f or US Cancer Therapeutics
Competitive Landscape
Leading Products
Table 28: Leading Products in the US Therapeutic Monoclonal Antibodies Market (2007): Percentage Breakdown of Revenues for Remicade, Avastin, Rituxan, Herceptin, Synagis, Lucentis, Erbitux, and Others (includes corresponding Graph/Chart)
Table 29: Leading Players in the US Therapeutic Monoclonal Antibodies Market (2007): Percentage Share Breakdown of Revenues for Genentech Inc, Centocor, MedImmune, Bristol Meyer's Squibb, Amgen, Hoffman-La Roche, and Others (includes corresponding Graph/Chart)
Focus on Key Players
Amgen, Inc
BD Biosciences
Biogen Idec
CMC ICOS Biologics, Inc
Dendreon Corporation
Eli Lilly and Company
Genentech, Inc
Human Genome Sciences
Immunomedics
Johnson & Johnson
Centocor
Ortho Biotech Products, L.P
Medarex, Inc
MedImmune, Inc
PDL BioPharma
Schering-Plough Corporation
Strategic Diagnostics Inc
Wyeth Pharmaceuticals
Product launches
Strategic Developments
B. Market Analytics
Table 30: US Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 31: US Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 32: US 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
2. Canada
A. Market Analysis
Strategic Developments
B. Market Analytics
Table 33: Canadian Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment -Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 34: Canadian Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 35: Canadian 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
3. Japan
A. Market Analysis
Strategic Developments
B. Market Analytics
Table 36: Japanese Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment -Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010, (includes corresponding Graph/Chart)
Table 37: Japanese Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 38: Japanese 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
4. Europe
A. Market Analysis
Biotechnology and Pharmacy Research
Monoclonal Antibody Based Products Market in Europe
European Therapeutic MAbs Market - An Overview
Approved Therapeutic Antibodies in Europe as of 2004
Need to Reduce Complexities, Time & Cost of mAb Development
Information Dissemination - Critical for Enhancing mAb Sales
Monoclonal Antibody Immunotherapy for NHL
MabThera - A Dominant MAb Drug in Europe
Emerging Radioimmunotherapy Products
Challenges for New Drug Development
B. Market Analytics
Table 39: European Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Geographic Region - France, Germany, Italy, UK & Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 40: European Long-term Projections for Monoclonal Antibody Based Products by Geographic Region - France, Germany, Italy, UK & Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 41: European Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 42: European Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 43: European 10-Year Perspective for Monoclonal Antibody Based Products by Geographic Region -Percentage Breakdown of Dollar Sales for France, Germany, Italy, The UK, and Rest of Europe for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart)
Table 44: European 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
4a. France
A. Market Analysis
Strategic Developments
B. Market Analytics
Table 45: French Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment -Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 46: French Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics (Cancer and Others) Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 47: French 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others), and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
4b. Germany
A. Market Analysis
Biotest AG- A Key Player
Product Launches
Strategic Developments
B. Market Analytics
Table 48: German Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment -Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 49: German Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 50: German 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
4c. Italy
Market Analysis
Table 51: Italian Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment -Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 52: Italian Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 53: Italian 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
4d. The United Kingdom
A. Market Analysis
Monoclonal Antibodies Market - An Overview
Strategic Developments
Product Launches
B. Market Analytics
Table 54: UK Recent Past, Current & Future Analysis for Monoclonal Antibody Based Products by Segment -Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 55: UK Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 56: UK 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others), and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
4e. Rest of Europe
A. Market Analysis
Key Players
Elan Corporations Plc (Ireland)
UCB Group (Belgium)
Strategic Developments
B. Market Analytics
Table 57: Rest of Europe Market for Monoclonal Antibody Based Products - Recent Past, Current & Future Analysis by Product Segment for Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 58: Rest of Europe Long-term Projections for Monoclonal Antibody Based Products by Segment - Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 59: Rest of Europe 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
5. Rest of World
A. Market Analysis
Australia
India
Strategic Developments
B. Market Analytics
Table 60: Rest of World Market for Monoclonal Antibody Based Products - Recent Past, Current & Future Analysis by Product Segment for Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2003 through 2010 (includes corresponding Graph/Chart)
Table 61: Rest of World (*) Market for Monoclonal Antibody Based Products - Long-term Projections by Product Segment for Therapeutics (Cancer and Others), and Diagnostics Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 62: Rest of World 10-Year Perspective for Monoclonal Antibody Based Products by Segment - Percentage Breakdown of Dollar Sales for Therapeutics (Cancer and Others),and Diagnostics Markets for 2003, 2008 & 2012 (includes corresponding Graph/Chart)
IV. COMPETITIVE LANDSCAPE
Total Companies Profiled: 123 (including Divisions/Subsidiaries - 144)
Region/Country Players
The United States 89
Canada 6
Japan 6
Europe33
France5
Germany 7
The United Kingdom6
Italy 1
Spain 1
Rest of Europe 13
Asia-Pacific (Excluding Japan) 9
Middle-East1