Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta

Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta


November 22, 2011
240 Pages - SKU: XGBR6690800
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Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta

Summary

GBI Research, the leading business intelligence provider, has released its latest research, “Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta”, which provides insights into the global pain management therapeutics market and market forecasts until 2017. The report provides an in-depth analysis of the top eight therapeutic indications for which pain management drugs are often prescribed, which includes fibromyalgia, neuropathic pain, migraine, cancer pain, osteoarthritis pain, rheumatoid arthritis pain, low back pain and post-operative pain. The report also examines the global pain management therapeutics treatment usage patterns for the covered indications. In addition, the report also includes insights into the pain management therapeutics R&D pipeline.

The report is built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis by GBI Research’s team of industry experts.

The global pain management therapeutics market has huge potential for growth due to the large population that is affected by medically significant pain. The market is growing at a moderate growth rate, driven by the cancer pain, low back pain and post-operative pain relief markets. In 2010, the global pain management therapeutics market was estimated at $28.6 billion, representing a CAGR of 5.3% between 2002 and 2010. The post-operative pain relief market, with sales of $5.9 billion in 2010, accounted for one fifth of the total pain management therapeutics market. The low back pain market, with sales of $4.9 billion, was the second largest market segment, with a share of 17% of the worldwide pain management therapeutics market. The low back pain market is followed by the cancer pain and neuropathic pain relief markets, accounting for 16% each of the global pain management therapeutics market.

The global pain management market is driven by anticonvulsant Lyrica and anti-depressant Cymbalta, which are expected to expire in 2013. By 2017, the global pain management therapeutics market is forecast to generate sales of $35.1 billion, representing a CAGR of 3.0% between 2010 and 2017. Other blockbuster drugs that are likely to drive the market in the forecast period include UCB Group’s Vimpat (lacosamide), Teva’s Fentora (fentanyl), J&J’s Nucynta (tapentadol), Pfizer’s Remoxy (oxycodone hydrochloride) and Orexo’s Abstral (fentanyl).

Scope
  • Data and analysis on the pain therapeutics market in the leading geographies of the world - the US, the UK, Germany, France, Italy, Spain, and Japan.
  • Annualized market data for the pain management therapeutics market from 2002 to 2010, with forecasts to 2017.
  • Market data on the therapeutic landscape, which covers fibromyalgia, neuropathic pain, migraine, cancer pain, osteoarthritis pain, rheumatoid arthritis pain, low back pain and post-operative pain therapeutics, including market size, market share, annual cost of therapy, sales volume and treatment usage patterns such as disease population and treated population.
  • Key drivers and restraints that have had a significant impact on the market and on each indication.
  • The competitive landscape of the global pain management therapeutics market, which includes companies such as Pfizer, Johnson & Johnson, Teva, Eli Lilly and several mid-size players such as Purdue Pharma, Endo Pharmaceuticals, and Forest Laboratories.
  • Key M&A activities and Licensing Agreements that took place from 2005 to 2010 in the global pain management therapeutics market.
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  • Develop key strategic initiatives by understanding the key focus areas and top selling pain management therapeutics molecules of leading companies.
  • Accelerate and strengthen your market position by identifying key companies for mergers, acquisitions and strategic partnerships.


Additional Information

GBI Research, the leading business intelligence provider, has released its latest research, “Pain Management Therapeutics Market to 2017 - Price Competition to Intensify Following Patent Expiries of Lyrica and Cymbalta”, which provides insights into the global pain management therapeutics market and market forecasts until 2017. The report provides an in-depth analysis of the top eight therapeutic indications for which pain management medications are prescribed, including fibromyalgia, neuropathic pain, migraine, cancer pain, osteoarthritis pain, rheumatoid arthritis pain, low back pain and post-operative pain. The report also examines the global pain management treatment usage patterns for the covered indications. In addition, the report also includes insights into the pain management R&D pipeline.

The report is built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis by GBI Research’s team of industry experts.

Global Pain Management Therapeutics Market to Witnesses Moderate Growth as Generic Share Continues to Rise

In 2010, the global pain management market was worth approximately $28.6 billion, representing a compound annual growth rate (CAGR) of 5.3% between 2002 and 2010. By 2017, the global pain management market is estimated to reach $35.1 billion, indicating a CAGR of 3.0% between 2010 and 2017. The major reason behind the decline in the growth rate is the decline in the annual cost of treating pain in different indications during 2010-2017. Although the market for management is highly competitive, blockbuster sales of Lyrica (pregabalin) and Cymbalta (duloxetine HCl) coupled with improved diagnosis of pain indications such as fibromyalgia and neuropathic pain are expected to drive the market in the future.

Pain Management Therapeutics Market, Global, Revenue Forecasts ($bn), 2002-2017

Source: GBI Research, American Academy of Pain Medicine, the American Pain Society, American Chronic Pain Association, National Fibromyalgia Association, Arthritis Association, Cancer Association

The global pain management market is expected to witness a series of patent expiries between 2009 and 2016, which includes some top selling drugs such as Cymbalta, Lyrica and Celebrex (celecoxib). While the current pain management market has a healthy pipeline and prospects for growth in the future, these factors will not be able to completely offset the challenge from generic competition. Therefore, while the pipeline ensures potential for attractive growth in the long term, Unmet Need for Better Management of Pain and Potential for Future Growth is Driving Companies to Invest in Research and Development

The research and development (R&D) pipeline for pain management is moderately healthy due to the presence of about 282 programs. These programs study drug candidates for the treatment of neuropathic pain and pain associated with fibromyalgia, cancer, migraine and osteoarthritis, rheumatoid arthritis, low back pain and post-operative pain.

Pain Management Therapeutics Market, Global, R&D Pipeline by Indication, 2010

Source: GBI Research, Company Websites, ClinicalTrials.gov

Nevertheless, the products in the pipeline do not look promising and may not provide better efficacy and safety levels compared to the drugs currently in the market. The pipeline is a mix of first-in-class and me-too products. The success of the first-in-class products will determine the future prospects for the industry. The high level of R&D activity indicates that the pain management market has potential for growth.

Lyrica and Cymbalta Drive the Pain Management Market

Lyrica (pregabalin) is the branded anticonvulsant product of Pfizer. Lyrica is indicated for the treatment of epilepsy, fibromyalgia and neuropathic pain. Lyrica, along with Neurontin (gabapentin), is the first line of therapy for the treatment of neuropathic pain, especially when tricyclic antidepressants are contraindicated. Lyrica is the only anticonvulsant which has been approved for the treatment of fibromyalgia. Lyrica generated revenue of $2.6 billion and $2.8 billion for Pfizer in 2008 and 2009 respectively. Eli Lilly’s Cymbalta is another major drug approved for fibromyalgia, chronic osteoarthritis pain and chronic low back pain. Cymbalta registered revenue of $2.6 billion and $3 billion in 2008 and 2009 respectively.

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