1 EXECUTIVE SUMMARY
Introduction
Introduction
Embryonic Vs. Adult Stem Cells
Key Findings
International Developments
Market and Applications Overview
Research Methodology
2 INTRODUCTION
Embryonic and Adult Stem Cells
Introduction
Embryonic Stem Cells
Political Debate
Cloning: Therapeutic Vs. Reproductive
Adult Stem Cells
Potential Applications for Stem Cell Therapies
Gene Therapy/Tissue Engineering
Neurological Therapies
Bone and Cartilage; Repair and Regeneration
3 MARKET ANALYSIS
Market Forecast and Sectors Affected by Stem Cell Therapeutics
Market Forecast
Alzheimer's; Cancer; Heart Disease
Wounds; Burns; and Skin Ulcers
Spinal Repair Therapies
Tissue Engineering
Bone Implants and Cartilage Regeneration
Organ Transplantation
Breast Cancer Therapies
Diabetes Therapies
New Heart Attack Therapeutics
New Products Will Face Competition
Gene Therapy
International Efforts
Market Drivers and Opportunities
R&D Funding
Government Funding/Population Issues/Partnerships
4 MARKET AND TECHNOLOGY CHALLENGES AND BARRIERS
Introduction
Introduction
Culture Difficulties
Key Challenges and Barriers
Key Restrictions
The Stem Cell Debates: Political and Biological
Quality Control
Other Challenges
5 STEM CELL TECHNOLOGIES
International Efforts
Scotland: Stem Cell Osteoblasts Could Help Osteoporosis
Germany: Patient's Own Stem Cells Restore Damaged Heart Muscle
Japan: Artificial Eyeballs and Other Research
Canada: So Simple? Stem Cells Regenerate Injured Mouse Pancreas
Israel: Human Heart Tissue Generated from Embryonic Stem Cells
Korea: Human Embryo Cloned
China: Stem Cells from Human-Rabbit Hybrid Embryo
Sweden Funds Stem Cell Research
UK: International Human Stem Cell Project
India/Switzerland
Growing; Storing; and Analyzing Stem Cells
Rare Adult Stem Cells As Multipotent As Embryonic?
Adult Stem Cells Might Not Trans-Differentiate after All
But Then Again
Serum-Free; Mouse-Cell Free Culture System
Another Serum-Free; Mouse-Cell Free Culture System
Private Funds Yield New Embryonic Lines
Human ESCs Stable in Culture over Long Time
Embryonic Skin Cells Committed at an Early Age
Blood Cells from ESCs May Protect against Transplant Rejection
Stem Cell-Specific Genes Analyzed
Stem-Cell Factor and Flt3-Ligand for Stem Cell Growth
One-Cell Genetics Lab-On-Chip
Cytometry Probes Effect of HIV on Stem Cells
New Freezing Method Keeps Stem Cells Viable
Scaffolds for Tissue Engineering
Temperature-Sensitive Hydrogel for Joint Repair
Fibrin/Polymer Matrix Slows Growth Factor Dissipation
Biorubber Makes Good Scaffold for Stem Cell Growth
A Collagen Bandage
Molecule Mimics Tissue Nanostructure for Scaffolds
Stem Cells + Scaffold + Growth Factors = New Tissues
Tissue Repair and Regeneration
Neurological Therapies
Cardiovascular Therapies
Bone and Cartilage
Diabetes
Cancer
Miscellaneous
Dedifferentiation
Regeneration by Dedifferentiation: No Stem Cells Needed?
More Dedifferentiation: Chemical Turns Muscle Cells back into Stem Cells
Engineering Whole Tissues
Functioning Liver Tissue Grown in a Bioreactor
Tissue-Engineered Joint from Stem Cells
Tissues Derived from Nuclear Transplantation Avoid Immune Rejection
Engineered Tissue Goes Chomp
CAD/CAM Meets Bioassembly of Live Tissue
Ex Vivo Gene Therapy
Stem Cell Gene Therapy for Blood Disorders
Gene Therapy Corrects Blistering Skin Disorder in Mice
Telomerase Gene Extends Lifespan of Adult Marrow Stem Cells
Mesenchymal Stem Cells Target Tumors
RNA Interference Tunes Gene Activity in Stem Cells
Cells of Knockout Pigs Acceptable to Human Immune System
Adult Stem Cells As Natural Gene Therapy
6 PATENTS AND CONTACT DETAILS
Patents
Patents - I
Patents - II
Patents - III
Patents - IV
Contact Details
Contact Details
7 FROST & SULLIVAN 2004 SCIENCE AND TECHNOLOGY AWARDS
Technology Innovation Award
Awards Description
Award Recipient
Technology Leadership Award
Award Description
Award Recipient
8 DECISION SUPPORT TABLES
Prevalence of Arthritis (Millions)
Worldwide Prevalence of Arthritis by Country (Millions)
Cardiovascular Prevalence as Percentage of Total Population
Cardiovascular Prevalence Per Country as Percentage of Total Population
Cardiovascular Prevalence (Millions)
Cardiovascular Disease Prevalence Per Country(Millions)
Number of Heart Transplants
Number of Heart Transplants Per Country
Number of Kidney Transplants
Number of Kidney Transplants Per Country