Countries covered: United States
US demand to rise 7.2% annually through 2015
US demand for drug delivery products is forecast to expand 7.2 percent annually to $133 billion in 2015. The best growth opportunities will emerge in specialized pharmaceutical formulations and administration devices that advance the nature of therapy for autoimmune conditions, cancer, heart disease, neurological disorders and other debilitating health problems. Included in this group are human monoclonal antibodies, polymer encapsulated nanomedicines and transdermal patches for breakthrough pain management. Infusion products and parenteral delivery devices with improved safety, infection prevention and ease-of-use features will also fare well in the marketplace. Among these devices are retractable syringes, needleless injectors, premixed IV systems and smart infusion pumps. Based on the complex nature of therapy and the high frequency of dosing requirements, central nervous system, respiratory and hormonal indications will command the largest and fastest growth by drug delivery products.
Chewable and orally disintegrating tablets to see good growth
Demand for oral drug delivery products will increase 4.3 percent annually to over $52 billion in 2015. Controlled-release formulations will command the largest share of sales, but will lose some growth momentum due to patent expirations on several large-selling sustained-release therapies. Chewable and orally disintegrating tablets, nanoparticulate medicines and transmucosal therapies will realize faster growth in demand spurred by new product introductions and the high valueadded nature of indications served.
Monoclonal antibodies to pace parenteral products
Demand for parenteral drug delivery products will reach $54.7 billion in 2015, up eleven percent annually from 2015. Monoclonal antibodies will lead gains as advances in biotechnologies contribute new and improved therapies for autoimmune disorders, cancer and various rate debilitating diseases. Polymer-encapsulated medicines will also see fast rising demand based on contributions to the improved bioavailality and reduced toxicity of advanced parenteral compounds. Safety-engineered prefillable syringes and IV catheters, along with bag/ vial infusion systems, will command the best growth opportunities among parenteral infusion products and delivery devices due largely to infection prevention advantages.
Patches to lead gains among other drug delivery systems
Other drug delivery products will post demand of $26.1 billion in 2015, up 6.6 percent annually from 2010. Prefilled dry powder and metered dose inhalers will retain the largest share of sales, spurred largely upward trends in prevalence of asthma and chronic obstructive pulmonary disease (COPD). Less favorably, growth opportunities for these devices will decelerate as patent expirations open up several widely prescribed inhalation therapies, including sales leader ADVAIR, to generic competition. Led by new next-generation drug-eluting stents with thinner struts and enhanced safety profiles, implantable drug delivery systems will generate rebounding demand in angioplasty procedures, reversing a recent sharp sales drop. Transdermal patches will realize the fastest growth among other drug delivery systems as new therapies for breakthrough pain and various central nervous system disorders replace less effective oral medicines.
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- INTRODUCTION
- I. EXECUTIVE SUMMARY
- II. MARKET ENVIRONMENT
- General
- Economic Factors
- Demographic Patterns
- Health Care Trends
- Health Insurance
- Medical Conditions
- Acute Conditions
- Chronic Conditions
- National Health Expenditures
- Medical Providers
- Hospitals
- Skilled Nursing Homes
- Outpatient Facilities
- Physicians
- Patient Activity
- Hospital Activity
- Surgical Procedures
- Outpatient Consultations
- Pharmaceutical Market Overview
- Regulation
- Research & Development
- Demand Patterns
- Therapeutic Classes
- Dosage Formulations
- Distribution Classification
- Commercial Status
- III. DRUG DELIVERY EXCIPIENTS
- General
- Polymers
- Polyethylene Glycol
- Acrylic Polymers
- Carbomers
- Methacrylate Copolymers
- Polyethylene Oxide
- Polyvinyl Alcohol
- Other Synthetic Polymers
- Cellulose Excipients
- Ethyl Cellulose
- Hydroxypropyl Methylcellulose (HPMC)
- Other Cellulose Excipients
- Minerals
- Mineral Hydrocarbons
- Petrolatum
- Mineral Oil
- Waxes
- Other Minerals
- Attapulgite
- Calcium Carbonate
- Calcium Silicate
- Electrolytes
- Other Excipients
- Sterile & Purified Waters
- Starch Compounds
- Cyclodextrins
- Dextrates
- Dextrin
- Maltodextrin
- Sugars & Polyols
- Sucrose
- Sorbitol
- Lactose
- Mannitol
- Natural Gums
- All Other Excipients
- IV. DRUG DELIVERY PRODUCTS OVERVIEW
- General
- Types of Drug Delivery Products
- Historical Market Trends
- Regulation
- Research & Development
- US Trade
- International Markets
- V. ORAL DRUG DELIVERY PRODUCTS
- General
- Controlled-Release Formulations
- Coated Products
- Diffusion Products
- Reservoir Products
- Chewable Tablets
- Nanoparticulate Formulations
- Orally Disintegrating Tablets (ODT)
- Transmucosal Formulations
- VI. PARENTERAL DRUG DELIVERY PRODUCTS
- General
- Therapeutic Monoclonal Antibodies
- Types of Monoclonal Antibodies
- Marketed Products
- Therapeutic Monoclonal Antibodies in Development
- Encapsulated Parenteral Drug Delivery Products
- Polymer-Protected Products
- PEG-Based Parenteral Therapies
- Other Polymer-Protected Parenteral Therapies
- Developmental Activities
- Liposomes
- Marketed Products
- Developmental Activities
- Infusion Products
- IV Administration Sets
- Premixed IV Solutions
- Infusion Pumps
- Other Infusion Products
- Enteral Feeding Supplies
- IV Accessories
- Parenteral Drug Delivery Devices
- Prefillable Syringes
- Injectors
- Cartridges
- Hypodermic Syringes
- IV Catheters
- Other Parenteral Delivery Devices
- VII. OTHER DRUG DELIVERY PRODUCTS
- General
- Inhalation Drug Delivery Products
- Dry Powder Formulations
- Types of DPIs
- Developmental Activities
- Metered Dose Formulations
- 3M Drug Delivery Systems
- Other Producers
- Implantable Drug Delivery Products
- Drug-Eluting Stents
- Other Implantable Drug Delivery Products
- Drug Inserts
- Brachytherapy
- Drug Pumps
- Transdermal Drug Delivery Products
- Transdermal Technologies
- Central Nervous System Agents
- Other Transdermal Therapies
- Hormones & Related Agents
- OXYTROL
- Cardiovascular Agents
- Nicotine Patches
- Scopolamine
- VIII. APPLICATIONS
- General
- Central Nervous System Agents
- Respiratory Agents
- Hormones & Related Agents
- Gastrointestinal Agents
- Cardiovascular Agents
- Anti-Infective Agents
- Nutritional Agents
- Genito-Urinary Agents
- Other Pharmaceuticals
- IX. INDUSTRY STRUCTURE
- General
- Market Share
- Competitive Strategies
- Mergers & Acquisitions
- Licensing & Related Agreements
- Marketing & Distribution
- Manufacturing
- Company Profiles
- Abbott Laboratories
- Amgen Incorporated
- Aptalis Pharma Incorporated
- AptarGroup Incorporated
- AstraZeneca plc
- Aveva Drug Delivery Systems, see Nitto Denko
- Axcan Intermediate Holdings, see Aptalis Pharma
- Baxa, see Baxter International
- Baxter International Incorporated
- Becton, Dickinson and Company
- Boehringer Ingelheim GmbH
- Boston Scientific Corporation
- Braun (B.) Melsungen AG
- Bristol-Myers Squibb Company
- Cephalon, see Teva Pharmaceutical Industries
- Conor Medsystems, see Johnson & Johnson
- Cordis, see Johnson & Johnson
- Eurand, see Aptalis Pharma
- Evonik Industries AG
- Facet Biotech, see Abbott Laboratories
- Genentech, see Roche Holding
- Genzyme, see Sanofi-Aventis
- GlaxoSmithKline plc
- Hospira Incorporated
- ImClone Systems, see Lilly (Eli)
- Janssen Pharmaceuticals, see Johnson & Johnson
- Johnson & Johnson
- Lilly (Eli) and Company
- Medingo, see Roche Holding
- Merck & Company Incorporated
- Nitto Denko Corporation
- Novartis AG
- Novo Nordisk A/S
- Ortho-McNeil-Janssen Pharmaceuticals, see Johnson & Johnson
- Pfizer Incorporated
- Roche Holding Limited
- Sanofi-Aventis
- Teva Pharmaceutical Industries Limited
- 3M Company
- Unilife Corporation
- West Pharmaceutical Services Incorporated
- LIST OF TABLES
- SECTION I -- EXECUTIVE SUMMARY
- Summary Table
- SECTION II -- MARKET ENVIRONMENT
- 1 Macroeconomic Indicators
- 2 Population by Age Group
- 3 Health Insurance Coverage of the US Population
- 4 Acute Conditions by Type
- 5 Chronic Conditions by Type
- 6 National Health Expenditures by Type
- 7 Medical Providers by Type
- 8 Patient Activity by Type & Volume
- 9 Pharmaceutical Demand by Therapeutic Class
- 10 Pharmaceutical Demand by Dosage Formulation
- 11 Pharmaceutical Demand by Distribution Classification
- 12 Pharmaceutical Demand by Commercial Status
- SECTION III -- DRUG DELIVERY EXCIPIENTS
- 1 Drug Delivery Excipient Demand by Product Group
- 2 Polymer Drug Delivery Excipient Demand by Type
- 3 Cellulose Drug Delivery Excipient Demand by Type
- 4 Mineral Drug Delivery Excipient Demand by Type
- 5 Other Drug Delivery Excipient Demand by Type
- SECTION IV -- DRUG DELIVERY PRODUCTS OVERVIEW
- 1 Drug Delivery Product Demand by Dosage Formulation
- 2 Drug Delivery Product Demand, 2000-2010
- 3 US Trade in Drug Delivery Products
- 4 World Drug Delivery Product Demand by Region
- SECTION V -- ORAL DRUG DELIVERY PRODUCTS
- 1 Oral Drug Delivery Product Demand by Type
- 2 Oral Controlled-Release Drug Delivery Product Demand by Type, Mode of Action & Application
- 3 Oral Coated Drug Delivery Product Demand
- 4 Oral Diffusion Drug Delivery Product Demand
- 5 Oral Reservoir Drug Delivery Product Demand
- 6 Chewable Tablet Demand by Therapeutic Class
- 7 Oral Nanoparticulate Product Demand by Application
- 8 Orally Disintegrating Tablet (ODT) Demand by Application
- 9 Transmucosal Product Demand
- SECTION VI -- PARENTERAL DRUG DELIVERY PRODUCTS
- 1 Parenteral Drug Delivery Product Demand by Type
- 2 Therapeutic Monoclonal Antibody Demand by Application
- 3 Therapeutic Monoclonal Antibodies Approved for US Sale
- 4 Encapsulated Parenteral Product Demand by Type & Application
- 5 Infusion Product Demand by Type
- 6 Parenteral Delivery Device Demand by Type
- SECTION VII -- OTHER DRUG DELIVERY PRODUCTS
- 1 Other Drug Delivery Product Demand by Type
- 2 Inhalation Drug Delivery Product Demand by Type
- 3 Dry Powder Inhaler (DPI) Product Demand
- 4 Metered Dose Inhaler (MDI) Product Demand
- 5 Implantable Drug Delivery Product Demand by Type & Application
- 6 Drug-Eluting Stent Demand
- 7 Other Implantable Drug Delivery Product Demand by Type
- 8 Transdermal Product Demand by Application
- SECTION VIII -- APPLICATIONS
- 1 Drug Delivery Product Demand by Application
- 2 Central Nervous System (CNS) Drug Delivery Product Demand by Type
- 3 Respiratory Drug Delivery Product Demand by Type
- 4 Hormone & Related Drug Delivery Product Demand by Type
- 5 Gastrointestinal Drug Delivery Product Demand by Type
- 6 Cardiovascular Drug Delivery Product Demand by Type
- 7 Anti-Infective Drug Delivery Product Demand by Type
- 8 Nutritional Drug Delivery Product Demand by Type
- 9 Genito-Urinary Drug Delivery Product Demand by Type
- 10 Drug Delivery Product Demand in Other Pharmaceuticals by Type
- SECTION IX -- INDUSTRY STRUCTURE
- 1 US Drug Delivery Product Sales by Company, 2010
- 2 Selected Acquisitions & Divestitures
- 3 Selected Cooperative Agreements
- LIST OF CHARTS
- SECTION IV -- DRUG DELIVERY PRODUCTS OVERVIEW
- 1 Drug Delivery Product Demand by Dosage Formulation, 2010
- SECTION V -- ORAL DRUG DELIVERY PRODUCTS
- 1 Oral Drug Delivery Product Demand by Type, 2010
- 2 Oral Controlled-Release Drug Delivery Product Demand by Type, 2010
- SECTION VI -- PARENTERAL DRUG DELIVERY PRODUCTS
- 1 Parenteral Drug Delivery Product Demand by Type, 2010
- SECTION VII -- OTHER DRUG DELIVERY PRODUCTS
- 1 Other Drug Delivery Product Demand by Type, 2010
- SECTION VIII -- APPLICATIONS
- 1 Drug Delivery Product Demand by Application, 2010
- SECTION IX -- INDUSTRY STRUCTURE
- 1 Drug Delivery Dosage Formulations, US Market Share, 2010
- 2 Drug Delivery Devices, US Market Share, 2010
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