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Receive a thorough overview of the evolving field of rapid viral testing with D&MD’s Rapid Viral Testing Report, including market forecasts through 2010. This Report will provide the most up-to-date survey of rapid viral testing technologies and products that are available, illustrated with recent case studies and providing analyses of savings and medical as well as logistical benefits.
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- Chapter 1: Executive Summary
- Chapter 2: The Rationale of Rapid Infectious Disease Testing
- What Does “Rapid” Mean in Infectious Disease Testing?
- When “Rapid” Means “Rapid and Easy:” Testing Outside the Laboratory
- Home Testing and Home Collection/Mail-In Tests
- Where Time Savings Can Make a Therapeutic Difference
- Healthcare Resource Allocation
- Targeted Screening
- Occupational Exposure
- Bioterrorism Countermeasures
- Regulatory Considerations for Rapid Viral Testing
- Privacy Issues
- Chapter 3: Current and Emerging Rapid Testing Technologies
- Testing Matrices
- Whole Blood and Dried Blood Spots
- Dried Blood Spots (DBS)
- Urine
- Saliva and Oral Mucosal Transudate
- Rapid Serological Tests
- Immunochromatography: The Lateral Flow Principle
- Flow-Through Devices
- Solid Phase Devices
- CANARY: An Example for an Unconventional Antigen Detection Principle
- Nucleic Acid Based Tests
- The Polymerase Chain Reaction (PCR) and its Derivative Technologies
- TaqMan and Modifications
- Loop-Mediated Isothermal (LAMP) Assay
- Conjugated Peptide Nucleic Acid (PNA) Tests
- Rapid Electron Microscopy
- Chapter 4: The Testing Targets and the Tests
- HIV Detection and Typing
- FDA-Approved HIV Antibody Tests
- OraQuick Rapid HIV-1/2 Test
- Reveal Rapid HIV Antibody Test
- Multi-Spot HIV-1/HIV-2 Test
- Uni-Gold Recombigen HIV Test
- HIV Rapid Genotyping: Monitoring Drug Resistance
- Hepatitis Viruses
- Hepatitis A and E
- Hepatitis B
- Hepatitis B Rapid Tests Worldwide
- Microarrays-Not yet a Factor in Hepatitis B Rapid Typing
- Hepatitis C
- HCV Genotyping
- Combined HIV and HCV Infection-A Mounting Challenge
- Febrile Respiratory Infections: Leading Killers Worldwide
- Influenza
- Severe Acute Respiratory Syndrome (SARS)
- Respiratory Syncytial Virus (RSV)
- Enteroviruses
- West Nile Virus
- Viral Hemorrhagic Fevers
- Dengue
- Ebola
- Herpes Simplex Viruses
- Infectious Mononucleosis
- Papillomavirus
- Smallpox-The Most Significant Viral Bioterrorism Agent
- Rabies
- Prion Diseases
- Chapter 5: Markets and Market Dynamics for Rapid Viral Tests
- HIV and HCV Diagnostics-Driven by Both Point of Care and Molecular Tests
- The Fluctuating Rapid Test Market for Respiratory Diseases
- Viral Hemorrhagic Fevers and West Nile Virus-Another Significant Potential for Rapid Tests
- International Developments
- A Paradigm Change is Imminent During 2005-2010
- Summary
- Chapter 6: Developers and Vendors: Selected Corporate Profiles
- Acon Laboratories
- Artus GmbH
- Bio-Rad Laboratories
- Becton Dickinson Diagnostic Systems
- Calypte Biomedical Corp.
- Genelabs Diagnostics Pte Ltd
- Inverness Medical Innovations, Inc.
- Medical Services International, Inc.
- MedMira Laboratories, Inc.
- OraSure Technologies, Inc.
- Roche Diagnostics
- Roche Molecular Systems, Inc.
- Saliva Diagnostic Systems, Inc.
- LIST OF EXHIBITS
- Exhibit 3.1 Lateral Flow Device Scheme
- Exhibit 3.2 Flow-Through Device Scheme.
- Exhibit 3.3 CANARY™ Biosensor Detection of Viral Pathogens.
- Exhibit 3.4 The Principle of the Polymerase Chain Reaction (PCR)
- Exhibit 3.5 The TaqMan Principle
- Exhibit 4.1 FDA-Approved Rapid HIV Test Kits
- Exhibit 4.2 Performance Characteristics of FDA-Approved Rapid HIV Tests Compared to a Typical FDA-Approved Immunoassay under Various Conditions of HIV Prevalence
- Exhibit 4.3 The OraQuick Test
- Exhibit 4.4 The BioRad Multi-Spot Rapid HIV-1/HIV-2 Test
- Exhibit 4.5 The Trinity Biotech Uni-Gold Recombigen HIV Assay
- Exhibit 4.6 Selected Internationally Available Rapid HIV Antibody Tests without FDA Approval
- Exhibit 4.7 Typical Serological Time Profile in Uncomplicated Hepatitis B
- Exhibit 4.8 Selected Internationally Available Rapid Hepatitis B Tests
- Exhibit 4.9 Transmission Routes for Hepatitis C Virus
- Exhibit 4.10 Estimated and Acute Cases of HCV Infection, USA 1982-2001
- Exhibit 4.11 Selected Internationally Available Rapid Hepatitis C Tests
- Exhibit 4.12 Performance Characteristics of Rapid Influenza Assays available in the United States (as per manufacturer data)
- Exhibit 4.13 Distribution of Dengue Fever, 2000
- Exhibit 4.14 Sequence-Predicted (left row) versus Actual (right row) Patterns of Microchip-Based Hybridization of Amplified Orthopox Virus Nucleic Acids using Fluorescence Detection
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