Chronic Organ Transplant Rejection: Opportunities Await Improved Therapies

Decision Resources
March 10, 2008
26 Pages - SKU: DECR1696140
License type:
Table of Contents Related Reports
Countries covered: United States

Introduction

The organ transplant market, though growing only slowly in recent years, offers substantial opportunities for drug developers. This market encompasses therapies that must be taken lifelong, ensuring a steady stream of revenue throughout a drug's life cycle. Another attractive feature of this market is that it can serve as a gateway to other, potentially more lucrative markets.

Get the Answers You Need to Shape Your Strategy
  • Although the organ transplant market has seen slow growth, certain segments of the market offer greater opportunities. What factors are constraining this market? Will growth accelerate in coming years? Which markets offer the greatest potential rewards?
  • Current anti-rejection therapies provide satisfactory efficacy, but their side-effect profi les are a safety concern. Which current therapies are associated with the most serious effects? What are the greatest unmet needs in this market? How can companies capitalize on these needs as they develop new therapies?
  • Two leading agents in this market, Astellas's Prograf and Roche/Chugai's Cellcept, will soon go off-patent. What will the advent of increased generic competition mean for the market? Which agents will become the new market leaders?
Scope
  • Biology of transplant rejection: immune response in tissue rejection, natural killer cell response, types of rejection, post-transplant survival rates.
  • Prevalence of organ transplantation: number of transplants performed per year (including projections through 2017), number of transplants per organ, number of transplants by age-group.
  • Current therapies: treatment after transplantation, commonly used maintenance therapies.
  • Market for anti-rejection therapies:emerging therapies, long-acting tacrolimus, CP-690550, belatacept.
  • Market outlook: drivers, constraints, development strategies.
Please note, the PDF e-mail from publisher version of this report is for a global site license.


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