Biotechnology Licensing: How Has the Balance of Power Shifted?

Decision Resources
October 21, 2005
19 Pages - SKU: DECR1212075
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An analysis of the pipelines of four "mega corporations" that emerged during the first half of the decade-AstraZeneca, GlaxoSmithKline, Pfizer, and Sanofi-Aventis-shows that although spending on R&D increased significantly between 1999 and 2004, the number of new chemical entities in late-stage research has declined for all four mega corporations. How successful has the pipeline enhancement process been in practice? This report examines the pipelines of the four mega corporations to see what lessons can be learned. We seek to determine the impact that the megamergers have had on pipelines-whether mergers have resulted in a greater "breadth" of activity across therapy areas and increased productivity or whether the amalgamation of pipelines has had a deleterious effect on R&D output. The question is vital for these corporations because their profitability over the coming decades will depend, to a considerable extent, on the ability of their R&D operations to bring new drugs to market.

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