Executive Summary
Chapter 1. Introduction
Chapter 2. High-Throughput Screening Discussion
2.1 Introduction
-Rising R&D Costs
- Accelerating Discovery through High-Throughput
2.2 Current High-Throughput Screening Market Breakdown
-High-Throughput Screening Market Trends
2.3 High-Content Analysis
2.4 Conclusion
Chapter 3. High-Content Analysis Overview
3.1 State of Cell Based Assays in Drug Development - Where Does High Content Analysis Fit?
-High-Content Analysis Customer Description
3.2 Current Needs, Most Valuable Assays, Best Opportunities for High-Content Analysis
-GPCR
-RNAi
3.3 Technical Considerations
-Time to Scan
-Sample Preparation
-Fixed Versus Kinetic Studies
3.4 Market Conditions
-Hardware Market Analysis
Chapter 4. High-Content Analysis Impact
4.1 Impact o n Systems Biology
4.2 Impact on Toxicology
Chapter 5. Market Change Analysis - Five Year Projections
5.1 High-Content Analysis Hardware System Model
5.2 Reagent Cost Model
5.3 Other Costs
5.4 Total Market
5.5 Challenges to Technology Adoption
5.6 Conclusion
Appendix. Companies Interviewed
Applied Precision
AstraZeneca
Atto Bioscience
Aventis
Axon
Bristol-Myers Squibb
Cellomics
ICCB (Harvard Medical School)
Molecular Devices
Pfizer
Roche
Schering-Plough
Wyeth
Glossary
Company Index