Next Generation Sequencing Generates Momentum

This report focuses on current and innovative NGS technologies, services and markets to answer such questions as;

• Which early NGS market entrants have been continually improving and updating their original systems?
• Who has introduced new scaled-down instruments to broaden the market?
• What Generation 2.5 systems featuring new detection technologies and single-molecule sequencing are now on the market?
• When will third generation of instruments led by nanopore technologies be entering the commercial feasibility stage?
• Why upstream sample handling is undergoing continual technological innovation?
• Which informatics providers are moving rapidly toward fully integrated systems to provide the rapid generation of actionable biological information?

Next Generation Sequencing Generates Momentum: Markets Respond to Technology and Innovation Advances describes these innovations and analyzes their impact on this extremely dynamic technology and market sector. We report on the:

• NGS systems on the market and those on the horizon
• Possible game changing innovations still in development
• NGS market dynamics for instruments and services
• Results of an Insight Pharma Reports’ user market survey
• Interviews with six experts on diverse aspects of NGS
• Analysis on how the field will likely develop over the next several years.

Next Generation Sequencing Generates Momentum: Markets Respond to Technology and Innovation Advances updates the product offerings from Roche/454, Illumina, Life Technologies (Ion Torrent), Complete Genomics (CGI), Helicos, Pacific Biosciences (PacBio). As well as NGS upstream sample preparation and downstream informatics, aspects of NGS that have developed into substantial and fast-growing markets of their own. Companies in the informatics space covered in this report include Geospiza, Accelrys, GenoLogics, CLC bio, GenomeQuest, Partek, and DNAStar and Ingenuity Systems.

Next Generation Sequencing Generates Momentum: Markets Respond to Technology and Innovation Advances looks at a number of new product and technology candidates in varying stages of development. As the report highlights, some candidates are mainly extensions of current technologies, while others represent something very different.

Large companies have entered the new technology race such as General Electric, IBM as well as Life Technologies with its Starlight system. Many small entrepreneurial companies are also covered in this report including GnuBio’s with its microreactors, Halcyon Molecular and ZS Genetics’ use of scanning transmission electron microscopy, Intelligent Bio-Systems’ 40 million five micron wells, NABsys, using a hybridization-assisted nanopore method, NobleGen’s approach involving preliminary replacement of each base by longer oligonucleotides prior to sequencing and LightSpeed Genomics where patents suggest involving novel optical scanning methodology.