Pharmaceutical Licensing Strategies: Best Practices In Deal-making, Valuations And Strategic Management
Business Insights
June 1, 2006 116 Pages - SKU: RET1315618
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With falling R&D productivity and continued healthcare cost containment and generic competition pushing down the returns available for successfully launched products, only those companies able to complement internal efforts with a strong partnering strategy will be able to remain competitive over the next five-to-ten years. Pharmaceutical licensing strategies: Best practices in deal-making, valuations and strategic management provides a detailed analysis of licensing strategies in the pharmaceutical and biotechnology industries. The report draws upon deal-making trend data, primary research survey results and a profile of best practices in pharmaceutical licensing in order to present a set of actionable recommendations for optimizing deal-making.
Key findings of the report:
- The larger biotech companies now have the resources and the capabilities to develop lead drugs to later stages of development before seeking a pharmaceutical partner, and are now able to compete with pharmaceutical companies for the best in-licensing deals from emerging biotech.
- While the value of licensing deals has risen markedly in the last 5 years, the volume of deals among the top companies has plateaued. Companies are increasingly seeking out long-term, multi-product, multi-indication collaborations rather than one-off transactional deals.
- Using independent and unbiased model inputs in the licensing valuation process limits areas of subjective disagreement, and allows deal terms to be maximized for both parties.
- A successful deal cannot only be judged by deal terms and revenues gained from the eventual product; the quality of the relationship between licensing partners is also equally important.
Key questions answered in this report:
- What are the best practice strategies in developing an effective win-win licensing deal?
- How does the licensing process differ for in-licensing and out-licensing companies?
- How do outside agencies, consultancies and investors help to support the licensing process?
- What can be done to optimize licensing deal values through collaborative evaluations?
- What lessons can be drawn from the key successful deals and deal-makers of the past 10 years?
- How is the value, volume and competition for licensing deals forecast to change over the coming year?
- Why are companies now forming more relationship-based licenses than ever before?
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Additional InformationTop five reasons to order your copy today:
- Understand how the dynamics of licensing deals have changed in the last 5 years, including the increasing complexity of multiple development compound deals and the shifting balance of power between the licensee and licensor.
- Gain access to a survey of over 140 licensing experts ensuring you implement optimal licensing processes and commit adequate resources to support deal-making.
- Profile the leading deals and deal-makers over the past 5 years, identify the key factors of success and apply the report’s actionable recommendations.
- Implement effective alliance management processes to ensure the success of your current licensing deals and become the partner of choice for the future.
- Apply the independent licensing valuation model presented in this report in order to begin more collaborative licensing negotiations and maximize the value of your deal for both parties.
- Executive Summary
- Introducing pharmaceutical licensing
- Licensing trends
- Licensing process
- Licensing valuations
- Licensing best practices
- Chapter 1 Introducing pharmaceutical licensing
- Summary
- Introduction
- The age of the partnership
- Definitions
- Report outline
- Chapter 2 Licensing trends
- Summary
- Introduction
- Headline deal trends
- Licensing deal partners
- Licensing deal types
- Licensing deal subjects
- Chapter 3 Licensing process
- Summary
- Introduction
- A complex process
- In-licensing versus out-licensing
- Licensing strategy
- Opportunity identification
- In-licensing
- Out-licensing
- Licensing evaluations
- General portfolio management
- Applications for licensing evaluations
- Deal-making and agreement
- Key elements of a pharmaceutical license agreement
- Post-deal management and analysis
- Alliance management
- Using outside agencies
- Chapter 4 Licensing valuations
- Summary
- Introduction
- Valuing deals
- Current best practices
- Deal-making valuation model
- Model inputs
- Evaluation modeling
- Model outputs
- Model refinements
- Chapter 5 Licensing best practices
- Summary
- Introduction
- Top licensing deals of the 21st century
- Genentech-Roche
- Idenix-Novartis
- Millennium-Ortho Biotech
- AstraZeneca-AtheroGenics
- Preferred licensing partners
- Leading in-licensing companies
- Novartis
- Leading out-licensing companies
- Cephalon
- Recommendations for the future
- Licensing trends
- Licensing process
- Licensing valuations
- Licensing best practices
- Chapter 6 Appendix
- Primary research survey
- Sources
- Index
- List of Figures
- Figure 2.1: Number and average value of top 10 pharmaceutical company licensing deals, 2001- 2005
- Figure 2.2: Expected change in number of licensing deals during 2006
- Figure 2.3: Expected change in average value of licensing deals during 2006
- Figure 2.4: Number of top 10 pharmaceutical company licensing deals by partner, 2001-2005
- Figure 2.5: Number of top 10 biotech company licensing deals by partner, 2001-2005
- Figure 2.6: Number of biotech out-licensing deals by partner, 2001-2005
- Figure 2.7: Number of top 10 pharmaceutical company licensing deals by deal type, 2001-2005
- Figure 2.8: Number of top 10 biotech company licensing deals by deal type, 2001-2005
- Figure 2.9: Proportion of product-based licensing deals by therapy area, 2001-2005
- Figure 2.10: Number of product-based licensing deals by therapy area, 2001-2005
- Figure 2.11: Number of R&D licensing deals by development stage, 2001-2005
- Figure 2.12: Number of biotech R&D licensing deals by development stage, 2001-2005
- Figure 3.13: Expected change in number of potential partners chasing each licensing deal during 2006
- Figure 3.14: Expected change in the length of time required to complete a licensing deal during 2006
- Figure 3.15: The pharmaceutical licensing process
- Figure 3.16: Parties involved in identifying potential licensing opportunities, 2006
- Figure 3.17: Parties involved in conducting due diligence for potential licensing opportunities, 2006
- Figure 3.18: Parties involved in the valuation and negotiation of potential licensing deals, 2006
- Figure 4.19: Information shared between partners during licensing negotiations, 2006
- Figure 4.20: Valuation techniques used in determining optimal licensing deal terms, 2006
- Figure 4.21: R&D costs by phase, 2000
- Figure 4.22: R&D lead times by phase, 2000
- Figure 4.23: R&D success probabilities by phase, 2000
- Figure 4.24: Drug market diffusion curve - product lifecycle
- Figure 4.25: Likelihood of outcomes for new phase I, phase II and phase III drugs
- Figure 4.26: Expected real values (non-discounted) for new phase I, phase II and phase III drugs
- Figure 4.27: Discounted expected real values for new phase I, phase II and phase III drugs
- Figure 4.28: Discounted expected real values for new phase I, phase II and phase III drugs (adjusted for lower R&D cost inflation)
- Figure 4.29: Deal outcomes for out-licensor
- Figure 4.30: Deal outcomes for in-licensor
- Figure 4.31: Share of expected deal outcomes by partner
- Figure 4.32: R&D costs by phase by therapy area, 2000
- Figure 4.33: R&D lead times by phase by therapy area, 2000
- Figure 4.34: R&D success probabilities by phase by therapy area, 2000
- Figure 4.35: Peak sales and year of peak sales by therapy area, 2000
- Figure 4.36: Discounted value of sales by therapy area, 2000
- Figure 5.37: In-licensing partner of choice, 2006
- Figure 5.38: Business development and licensing department, Novartis
- Figure 5.39: Licensing process at Novartis
- Figure 5.40: Out-licensing partner of choice, 2006
- Figure 6.41: Licensing trends survey respondents by company focus
- Figure 6.42: Licensing trends survey respondents by functional responsibility
- Figure 6.43: Licensing trends survey respondents by licensing responsibility
- List of Tables
- Table 4.1: R&D cost by phase and peak sales, 2006 (expressed in 2006 dollars)
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