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2007 Antibody Report: Current Trends and Future Outlook

Biocompare
March 19, 2007
94 Pages - SKU: BCOM1475585

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The 2007 Antibody Report is composed of a market overview and an introduction to the Anti¬body Survey, which contains questions about antibodies and related applications and methods that researchers are using. The report also includes a discussion of the survey results and conclusions and recommendations drawn from both an analysis of the antibody market and the survey data. The market overview describes the use of antibodies in a wide array of disciplines, ranging from basic proteomics to diagnostics and disease therapeutics. Antibodies represent the largest seg¬ment of biotechnology reagents currently in use today, bringing in over $8.8 billion last year alone.

Antibodies are critical components of certain research methodologies, including protein electro¬phoresis, protein and antibody microarrays, and cell-based immunoassays. Detection of antibody interactions is also an important market, creating large revenue shares for fluorescent, chemilu¬minescent, and radioactive probes. Fluorescent probes alone captured the largest market share of $2.5 billion in 2005 and is expected to approach $4 billion by 2010. Increased antibody specificity was realized with the development of monoclonal antibodies (mAbs) that target a single protein epitope. Such an advance has allowed the rapid determina¬tion of molecular structures and the detection of minute amounts of proteins in clinical samples. Such inroads into clinical diagnostics has manifested in revenues that top $6 billion annually and continue to grow by over 6% each year. Presently, about 18 mAbs are approved by the FDA for the treatment of various diseases. With a complicated process required for production, mAbs are an expensive therapeutic option that needs additional optimization and manufacturing facilities to bring prices down.

Survey Introduction

The 2007 Antibody Survey is designed to provide life science vendors of antibodies and related supplies with a better understanding of how their products are used in the research environment and how their company specifically rates among the survey participants. Data were gathered from questions regarding the types and number of antibody-based applications performed per week and whether this number is expected to change, how often antibodies are purchased and whether the purchases are for never-before purchased reagents to new antigens, new conjugates, or new species, whether consumers shop around prior to making an antibody purchase and what the top criteria are when shopping for a new antibody, the top vendors that come to mind when one thinks of antibodies, the specific types of antibodies used and from which companies they are purchased, how these companies rate in terms of products and services, how much money is spent monthly for antibody purchases, how many people work in the laboratory, what types of custom services are used in the laboratory, whether there are specific targets, species, or applications for which antibodies cannot be found commercially and what these desired reagents are, the biggest technical problem with antibody-based methods, how often a vendor is contacted for technical support regarding antibody-related issues, how important specific vendor web site content is and whether such characteristics influence purchasing decisions, which commercially available second antibody conjugates are used, whether bulk antibodies are used, and where one looks for antibod¬ies to purchase. With this information, vendors will be able to structure marketing campaigns to address consumer needs, as well as focus product development in areas of greatest interest to those using antibodies in their research.

I. Report Introduction
II. Market Overview
III. Survey Introduction and Methodology
IV. Discussion of Survey Findings
V. Conclusion/Recommendations
VI. Appendix I: Questionnaire
VI. Appendix II: Presentation of Survey Data: i. Demographic Survey Data; ii. Antibody Survey Data
VIII. Other Survey Data: i. Top of Mind Antibody Companies; ii. Company/Antibody Type Results
Demographic Questions: a. Country; b. Institution Type; c. Title; d. Key Areas of Research or Work; e. Purchasing Authority
Antibody Questions: a. Do you currently use antibodies in your research or work?; b. What types of antibody-based applications do you perform or plan to perform? (Select all that apply); c. Please estimate how many antibody-based applications you perform on a weekly basis. (e.g. western blots, immunoassays, affinity purifications, etc.) open-ended; d. How do you expect this number to change over the next 12 months?; e. How often do you purchase antibodies?; f. How often do you purchase the following antibodies you have never purchased before? (separate set of response options for each one); • A New Antigen; • A New Conjugate; • A New Species; h. Which of the following best describes your typical antibody purchase?; i. What are the top three criteria you use when shopping for a new antibody?; j. What are the top companies that come to mind when you think of antibodies? (Please list as many as you can) open-ended; k. Which of the following types of antibodies do you use? (Select all that apply); l. From which company(s) do you purchase those antibody type(s)? (A separate question is given for each antibody type chosen); m. How would you rate the following product and service characteristics of the antibody suppliers you selected? (Only the selected suppliers will appear); Antibody Sensitivity; Antibody Specificity; Value; Usefulness of Website; Technical Support; n. How many people are in your lab?; o. Please estimate how much money your laboratory spends on antibodies per month.; p. What type of CUSTOM services do you use or plan to use? (Select all that apply); q. Are there antibodies against specific targets for which you have not been able to find a supplier?; r. Are there antibodies to certain species for which you have not been able to find a supplier?; s. Are there antibodies for particular applications for which you have not been able to find a supplier?; t. Please list 1 to 3 specific targets for which you have not been able to find an antibody. (open-ended); If no target is a particular protein modification, please specify amino acid and residue number.; Target 1 ___________________; Target 2 ___________________; Target 3 ___________________; u. Please name at least one antibody and species for which you can’t find a supplier.; v. Please name at least one antibody and application for which you can’t find a supplier.; w. Which of the following would you identify as the biggest technical problem with your antibody-based methods?; x. How often do you call or email a supplier for technical help with an antibody?; y. Please rate the following characteristics of an antibody supplier's web content.; z. Assume the quality of an antibody (i.e. specificity, sensitivity) is the same among suppliers.; aa. Please rate the following characteristics on how important each is in your decision to purchase from one supplier over another.; bb. Which of the following commercially available secondary antibody conjugates do you prefer to use? (Select all that apply); cc. Do you currently use or plan to use bulk quantities of antibodies?; dd. What is the antigen and species of the bulk antibody you use or plan to use? (e.g. Mouse anti-human CD42a) (open-ended); ee. Where do you look for antibodies? (Select all that apply)

2007 Antibody Report: Current Trends and Future Outlook

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