About BioSeeker Group
Our Five Steps to Creating Success in Intelligence
Databases
Reports
Analytical Tools
Consulting
Intelligence Partnership
Executive Summary
Methodology
Information Sources
Selection of Companies
Continents
Cluster Definitions and Limitations
R&D Definitions and Limitations
Analysts
Abbreviations
Introduction
Hepatitis C
Transmission
Genotypes
Current Drugs and Therapies targeting HCV
Pegylation Improves Efficacy and Administration
The Launch of Generic Ribavirin
Disturbing Side Effects
Drug Development Obstacles and Promises
HCV Market Development - A Multibillion Market Facing Changes
HCV Pharmaceutical Market in for a Stagnation in Growth
The Battle of Equals in Interferon - Affects the Entire HCV Market
How Schering-Plough Wants to Regain World Leadership After Loosing the 1st Round to Roche- The 2nd Round
World Business Interest in HCV
The Competitive Landscape of HCV Alliances
Companies Between Powerful Clusters - Are They of Strategic Value?
The HCV Cluster Analysis
Cluster I: The Screening Cluster
Cluster II: Out-licensing as a Business Model for HCV
Cluster III: The RNA Drug Discovery Creates Interest
Cluster IV: Future Success Lies in Co-Development?
Cluster V: Cluster of a Market Leader
Cluster VI: A Phase II Drug Cluster
Cluster VII: Cluster of Small Pharma: Do They Challenge?
Singles or Non-cluster HCV Companies?
R&D Diversity in HCV
Just About How Innovative is the Industry?
World Review on HCV Drug & Vaccine Development
Introduction
Top Five Countries
Latest Progress on Animal Models - Do they deliver?
Surrogate Animal Models
Human-Mice Chimeric Models
Using Stem-Cells
Transgenic Models
Pharmaceutical Drug Development
What Demands are Raised on New HCV Drugs?
Interferon will Continue to Dominate - But for How Long?
Ongoing Strategies to Enhance Interferon-based Therapies
Oral Interferon Inducers
Other Therapies That Modulate Host Immune Responses
Anti-HCV immunoglobulins - How do They Evolve?
The Power of HCV Inhibitors
Status and Advancement of RNA dependent RNA polymerase inhibitor
Status and Advancement of Serine-protease inhibitor
Status and Advancement of IMPDH inhibitor
Status and Advancement of P7 inhibitors
Is the Future Small Molecular Drugs?
Gene and Cell therapy Programs - An Alternative Route for Fighting HCV?
Ribozymes - Targets and Mechanisms in fighting HCV
The Never Ending Fight in Fibrosis
Non-Survival Drugs and Drugs on Hold
Mechanism versus Target - An Inventory of the Current Status
Partnering in HCV Drug Development
Progress in Prophylactic and Therapeutic HCV Vaccine Development
Prophylactic Vaccines Development
With a Strong Alliance in the DNA Vaccine Business
Therapeutic Vaccine Development
Who Will Be First With a Vaccine?
Partnering in HCV Prophylactic and Therapeutic Vaccine Development
Conclusion
Disclaimer
Liability
Completeness
Appendix A. Selected Key Company Profiles
Akros Pharma Inc
Anadys Pharmaceuticals
Boehringer Ingelheim GmbH
Chiron Corporation
F Hoffmann-La Roche
Collaborations
Hayashibara Biochemical Laboratories Inc
HemispheRx Biopharma
Indevus Pharmaceuticals Inc
Innogenetics NV/SA
InterMune Pharmaceuticals Inc
ISIS Pharmaceuticals Inc
Mitsubishi Pharma Corporation
Nektar Therapeutics
Schering-Plough Corporation
SciClone Pharmaceuticals Inc
Serono International S.A.
Tripep AB
Valeant Pharmaceuticals International
Viragen, Inc.
XTL Biopharmaceuticals Ltd