Optimizing Synthetic RNAi: Perspectives from the Pharmaceutical and Biotech Industry
BioInformatics, LLC
December 1, 2006 115 Pages - SKU: BIF1492282
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The price of this report has been reduced due to its age.
This report identifies the RNAi research objectives of pharmaceutical and biotech scientists and present siRNA customer purchasing preferences by key experimental design parameters
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- Section 1. Analysis and Interpretation of Survey Results
- Executive Overview
- Study Objectives
- Customer Profile
- Research Objectives
- Experimental Design
- Product Requirements
- Market Potential
- Throughput and Market Growth
- Future Trends
- Supplier Performance
- Preferred Suppliers
- Customer Satisfaction
- Brand Share
- Brand Health
- Section 2. Study Methodology and Demographics
- Methodology
- Definition of Terms
- Demographics
- Questionnaire
- Section 3. Presentation of Survey Data
- Experimental Design
- Currently use synthetic siRNA
- Primary research objective of RNAi experiments
- Primary species studied in RNAi research
- Cell types primarily used
- Typical method of measuring the effectiveness of RNAi-induced gene silencing
- Percent reduction in gene expression that is usually required
- siRNA Selection
- Percentage of total RNAi experiments for which each type of synthetic siRNA is used
- Preferred type of siRNA
- Synthesis scale typically ordered for preferred type of siRNA
- Order turn-around time normally required for preferred type of siRNA
- Typical specifications for preferred type of siRNA
- Strandedness
- Quantity
- Format
- Level of purification usually ordered for preferred type of siRNA
- Most common modification ordered for preferred type of siRNA
- Preferred method for ordering pre-designed or validated siRNA
- Primary way of designing custom siRNA
- Experimental Throughput
- Typical number of unique synthetic siRNAs utilized per gene target
- Average number of gene targets analyzed per month
- Expected change in the number of gene targets analyzed
- Choosing the siRNA Supplier
- Brands of synthetic siRNA currently used
- Primary brand of synthetic siRNA
- Percentage of RNAi experiments for which each brand of siRNA is used
- Relative amount of money spent on each brand of siRNA
- Evaluating the Primary Supplier’s Performance
- Satisfaction with specific product features of synthetic siRNA from primary supplier
- Formats available
- Modifications available
- Purification options
- Purity
- Reduction of target gene expression
- Specificity of gene suppression
- Stability in cells
- Time-to-results
- Transfectability
- Overall satisfaction with synthetic siRNA from primary supplier
- Happiness with the performance of synthetic siRNA from primary supplier
- Familiarity with other RNAi products from primary supplier
- Level of acceptability of synthetic siRNA prices from primary supplier
- Ease of obtaining synthetic siRNA from primary supplier
- Helpfulness of customer service from primary supplier
- Helpfulness of technical service from primary supplier
- Likelihood of recommending synthetic RNAi products from primary supplier to a colleague
- Future Trends in Nucleic Acid-Based Gene Silencing
- Identifying which molecules would be the most useful in advancing research goals in:
- Gene function analysis
- Genome-wide screening
- Therapeutic applications
- Improvement to siRNA that would most convince scientists to try a new supplier’s siRNA
- DemographicsSection
- 4. Appendices
- Insights and Perspectives
- Cross-Tabulations of Survey Data
- Other Recent Publications
- About BioInformatics
- Our Valued Clients
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