Labeling and Linking Agents for Immunoassays and Gene Probes
BCC Research
October 1, 2011 416 Pages - SKU: WA6669391
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Countries covered: United States
An overview of the technological developments in the market for labeling and linkage agents for immunoassays and gene probes
Analyses of global market trends, with data from 2009 and 2010, estimates for 2011, and projections of compound annual growth rates (CAGRs) through 2016
The most current and reliable information on consumption of probes and related chemicals in enzyme immunoassay
Estimates of the global supply-and-demand scenario broken down by applications and regions
Comprehensive profiles of major companies involved in the industry and their market shares.
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Additional InformationINTRODUCTION
OBJECTIVES AND GOAL OF THE STUDY
This study provides the reader with a detailed analysis of the current application and consumption and future growth potential of immunoagents, gene probes, and molecular diagnostics. This study also analyzes the recent technological developments, future industry trends, and emerging business opportunities. Such information will facilitate the investment decisions and strategic planning for business managers.
Immunoassays are used to determine antibody or antigen levels in a variety of disease situations. Gene probes explore the DNA makeup of microorganisms causing infection and of the gene structure of cellular mutations involved in cancer diabetes, coronary disease, etc. Molecular diagnostics is an emerging science that studies cellular biomarkers that are related to gene expression and that also develops assays to serve as companion diagnostic tests to allow physicians to better structure treatment of diseases.
- CHAPTER ONE: INTRODUCTION
- OBJECTIVES AND GOAL OF THE STUDY
- REASONS FOR DOING THE STUDY
- SCOPE OF THE STUDY
- TARGETED AUDIENCE
- METHODOLOGY
- ANALYST CREDENTIALS
- RELATED REPORTS
- BCC ONLINE SERVICES
- DISCLAIMER
- CHAPTER TWO: SUMMARY
- SUMMARY TABLE MARKETS FOR IMMUNOAGENTS, PROBES AND MOLECULAR DIAGNOSTICS, THROUGH 2016 ($ MILLIONS)
- SUMMARY FIGURE MARKETS FOR IMMUNOAGENTS, PROBES AND MOLECULAR DIAGNOSTICS, 2009-2016 ($ MILLIONS)
- CHAPTER THREE: TECHNOLOGY OVERVIEW
- IMMUNOASSAY TECHNOLOGY
- QUALITATIVE AND QUANTITATIVE IMMUNOASSAYS
- APPLICATIONS FOR IMMUNOASSAY TECHNIQUES
- COMPARISON OF IMMUNOASSAYS WITH CONVENTIONAL METHODS
- HIGH SENSITIVITY
- HIGH ACCURACY
- SPEED
- COST FACTORS
- METHODS OF IMMUNOASSAYS
- IMMUNOPRECIPITATION
- PARTICLE IMMUNOASSAYS
- RADIOIMMUNOASSAY (RIA)
- Immunoradiometric Assays
- IMMUNONEPHELOMETRY
- ENZYME IMMUNOASSAY (EIA)
- Enzyme-Linked Immunosorbent Assays (ELISA)
- FLUORESCENT IMMUNOASSAY (FIA)
- Fluorescence Polarization (FP): A Variation of FIA
- CHEMILUMINESCENT ASSAY (CLIA)
- IMMUNOASSAY TECHNIQUES
- MONOCLONAL-POLYCLONAL (MOAB-POAB) SANDWICH IMMUNOASSAY
- COMPETITIVE INHIBITION IMMUNOASSAY
- ANTIGEN-DOWN IMMUNOASSAY
- RAPID IMMUNOASSAYS
- GENE PROBE TECHNOLOGY (NUCLEIC ACID ASSAYS)
- DNA PROBES UTILIZED FOR ASSESSING TUMOR GENES IN PATIENT SPECIMENS
- TABLE 1 COMMONLY USED CHEMILUMINESCENT COMPOUNDS
- GENE PROBES
- MOLECULAR BEACONS
- TABLE 2 COMMON MOLECULAR BEACON AND QUENCHER COMBINATIONS
- DETECTION OF BACTERIAL CONTAMINATION IN FOODS
- CHIP-BASED NUCLEIC ACID ASSAY
- REPORTER GENE ASSAY
- TABLE 3 FDA APPROVED NUCLEIC ACID TEST USING DNA PROBE TECHNOLOGIES
- CHAPTER FOUR: OVERVIEW OF PROBES AND RELATED CHEMICALS
- RADIOACTIVE COMPOUNDS
- TABLE 4 PROPERTIES OF RADIOACTIVE ISOTOPES USED IN RADIOACTIVE LABELED PROBES
- ENZYMES/ENZYME SUBSTRATES
- FLUORESCENT COMPOUNDS
- CHEMILUMINESCENCE COMPOUNDS
- GENE PROBES
- CONSTRUCTION OF GENE PROBES
- PROBE LABELING
- RADIOACTIVE PROBES USED IN DIAGNOSTIC IMAGING
- TABLE 5 RADIONUCLIDES COMMONLY USED FOR DIAGNOSTIC IMAGING
- TABLE 6 USE OF RADIOACTIVE PROBES − THYROID IMAGING
- TABLE 7 ADDITIONAL USE OF ISOTOPES IN THYROID SCANNING
- TABLE 8 RADIO-LABELED ANTIBODIES FOR DIAGNOSIS OF SPECIFIC CANCE8S
- TABLE 9 USE OF RADIOACTIVE PROBES IN DIAGNOSIS OF THYROIDISM
- TABLE 10 USE OF RADIOACTIVE PROBES − RADIOCARDIOGRAPHY
- TABLE 11 USE OF RADIOACTIVE PROBES − TUMOR IMAGING
- TABLE 12 USE OF RADIOACTIVE PROBES − CANCER TREATMENT
- TABLE 13 USE OF RADIOACTIVE PROBES − DETERMINATION OF CIRCULATION RED CELL MASS/PLASMA VOLUME
- TABLE 14 USE OF RADIOACTIVE PROBES − DETERMINATION OF BLOOD FLOW
- TABLE 15 USE OF RADIOACTIVE PROBES − STOMACH IMAGING
- TABLE 16 USE OF RADIOACTIVE PROBES − TREATMENT OF LEUKEMIAS
- TABLE 17 USE OF RADIOACTIVE PROBES − STUDY OF GASTROINTESTINAL PROTEIN LOSS
- TABLE 18 USE OF RADIOACTIVE PROBES − SCANNING LUNGS/BRAIN
- TABLE 19 USE OF RADIOACTIVE PROBES − MYOCARDIAL STUDIES
- TABLE 20 USE OF RADIOACTIVE PROBES − HEART IMAGING
- TABLE 21 USE OF RADIOACTIVE PROBES − CEREBRAL PERFUSION IMAGING
- TABLE 22 USE OF RADIOACTIVE PROBES − BONE IMAGING
- TABLE 23 USE OF RADIOACTIVE PROBES − LUNG IMAGING
- HEPATOBILIARY IMAGING
- RETICULOENDOTHELIAL SYSTEM
- TABLE 24 USE OF RADIOACTIVE PROBES − RENAL IMAGING
- TABLE 25 USE OF RADIOACTIVE PROBES − MALIGNANT AND INFLAMMATORY REGIONS
- TABLE 26 USE OF RADIOACTIVE PROBES − AUTORADIOGRAPHY
- TRENDS IN RADIOLABELED ANTIBODY THERAPY
- RADIOPHARMACEUTICAL MARKET
- ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA) ASSAY PROCEDURES
- TABLE 27 COMMON TYPES OF ELISA ASSAY
- A CAPTURE EIA IS DESIGNED TO DETECT A SPECIFIC TYPE OF ANTIBODY, SUCH AS IGG OR IGM.
- TABLE 28 ENZYMES AND SUBSTRATES USED IN ELISA ASSAYS
- FLUORESCENCE COMPOUNDS
- TABLE 29 COMMONLY USED FLUOROPHORES IN FIA
- TABLE 30 FLUOROPHORES AND THEIR APPLICATIONS
- TABLE 31 FLUOROPHORES AND THEIR APPLICATIONS
- FLUORESCENT DOT IMAGING
- MOLECULAR IMAGING AND OPTICAL IMAGING
- OPTICAL IMAGING
- TABLE 32 RADIO-PROBES USED IN MOLECULAR IMAGING
- CHEMILUMINESCENT COMPOUNDS
- TABLE 33 COMMONLY USED CHEMILUMINESCENT COMPOUNDS
- TABLE 34 BLOTTING METHODS DEVELOPED FOR BIOMOLECULAR SPECIES
- FLOW CYTOMETRY
- CLINICAL APPLICATIONS OF FLOW CYTOMETER
- TABLE 35 FLUOROCHROME DYES USED IN MOLECULAR DIAGNOSTICS AND MOLECULAR PROBES
- CHAPTER FIVE: MARKETS FOR IMMUNOAGENTS, AND MOLECULAR DIAGNOSTICS BY APPLICATION SECTORS
- CHANGES IN THE GLOBAL MARKETS FOR IMMUNOGENIC PROBES
- TABLE 36 LIST OF FDA-APPROVED DRUGS THAT HAVE BIOMARKER INFORMATION INCLUDED IN THEIR LABELING
- TABLE 37 GLOBAL MARKET FOR IMMUNOAGENTS, PROBES, AND MOLECULAR DIAGNOSTICS BY APPLICATION SECTORS, THROUGH 2016 ($ MILLIONS)
- TABLE 38 DIAGNOSTIC CATEGORIES FOR FAILED DRUG CLINICAL TRIALS IN PERIOD 2008-2016
- TABLE 39 GLOBAL MARKET BY MATERIALS FOR PROBES IN IMMUNOASSAYS, THROUGH 2016 ($ MILLIONS)
- TABLE 40 GLOBAL MARKET BY MATERIALS FOR PROBES IN IMMUNOASSAYS INCLUDING MOLECULAR ANTIBODY THERAPY, THROUGH 2016 ($ MILLIONS)
- TABLE 41 REGIONAL SHARE OF THE MARKET FOR IMMUNOAGENTS, PROBES, AND MOLECULAR DIAGNOSTICS, THROUGH 2016 ($ MILLIONS)
- POINT-OF-CARE TESTS
- REQUIREMENTS FOR POC DEVICES
- TABLE 42 FDA CRITERIA FOR CATEGORIZING POTENTIAL POC TEST
- TABLE 43 TYPES OF POC TESTS WITH AUTOMATIC WAIVED STATUS
- TABLE 44 GLOBAL REVENUES FROM POC TESTING, THROUGH 2016 ($ MILLIONS)
- TABLE 45 GLOBAL MARKET FOR IN VITRO DIAGNOSTICS POC TESTS BY APPLICATION SECTORS, THROUGH 2016 ($ MILLIONS)
- TABLE 46 GLOBAL DISTRIBUTION OF IN VITRO DIAGNOSTICS POC TESTS BY REGION, 2010 ($ MILLIONS)
- MOLECULAR DIAGNOSTICS TESTS
- MOLECULAR DIAGNOSTICS REVENUE PROJECTIONS
- TABLE 47 GLOBAL REVENUES FROM MOLECULAR DIAGNOSTICS TESTS, THROUGH 2016 ($ MILLIONS)
- FDA-APPROVED MDX TESTS
- TABLE 48 CURRENT FDA APPROVED MOLECULAR DIAGNOSTICS TESTS
- TABLE 49 MOLECULAR DIAGNOSTICS SYSTEMS CURRENT IN COMMERCE 2011
- INFECTIOUS DISEASE TESTING
- TABLE 50 FDA-APPROVED INFECTIOUS DISEASE TESTS
- NEXT-GENERATION MOLECULAR DIAGNOSTICS
- U.S. PATENTS FOR MOLECULAR DIAGNOSTICS
- TABLE 51 NUMBER OF U.S. PATENTS ISSUED FOR MOLECULAR DIAGNOSTICS DURING THE PERIOD, THROUGH 2010
- TABLE 52 NUMBER OF U.S. PATENTS ISSUED TO UNIVERSITIES DURING THE PERIOD, THROUGH 2010
- THE RISE OF COMPANION DIAGNOSTICS
- BLOOD BANK IMMUNE TESTING
- FOOD TESTING IMMUNOASSAYS
- FORENSIC, BIOTERRORISM, AND PATERNITY MARKETS
- FORENSICS
- PATERNITY AND MATERNITY TESTING
- BIOTERRORISM
- MERGERS AND ACQUISITIONS
- TABLE 53 PHARMACEUTICAL AND BIOTECHNOLOGY MERGERS AND ACQUISITIONS IN 2010
- TABLE 54 MAJOR ACQUISITIONS IN BIOPHARMACOLOGY/BIOTECHNOLOGY IN 2009
- TABLE 55 MAJOR MERGER AND ACQUISITION ACTIVITY IN BIOTECH INDUSTRY DURING THE PERIOD 2005 THROUGH 2008
- WORLDWIDE IMMUNOASSAY AND MOLECULAR DIAGNOSTICS ACTIVITY
- TABLE 56 DISTRIBUTION OF GLOBAL REVENUES FOR IMMUNOASSAYS, GENE PROBES, AND MOLECULAR DIAGNOSTICS, 2010
- JAPAN
- CHINA
- RUSSIA
- BRAZIL
- CHAPTER SIX: COMPANY PROFILES
- MARKET SHARE OF MAJOR COMPANIES
- TABLE 57 MARKET SHARE OF MAJOR COMPANIES IN THE IMMUNOASSAY AND MOLECULAR DIAGNOSTICS AREAS, 2010
- ABBOTT LABORATORIES
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- IMMUNOASSAY
- TABLE 58 REPRESENTATIVE IMMUNOASSAY PRODUCTS AND AUTOMATED SYSTEMS (ARCHITECT SERIES) FOR THEIR ANALYSIS
- GENE PROBE AND MOLECULAR DIAGNOSTICS
- AFFYMETRIX
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- BECKMAN-COULTER
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- BIOMÉRIEUX
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- TABLE 59 BIOMÉRIEUX BIOMARKERS
- BIO-RAD LABORATORIES
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- GE HEALTHCARE LIFE SCIENCES
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- GENENTECH, INC.
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- TABLE 60 GENENTECH PRODUCTS IN PRODUCTION
- GEN-PROBE INCORPORATED
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- TABLE 61 GEN-PROBE STANDARDIZED ANTIBODIES
- LIFE TECHNOLOGIES
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- TABLE 62 LIFE TECHNOLOGIES’ CELL-LIGHT MOLECULAR SIGNALING DYES
- MILLIPORE CORPORATION (MERCK KGAA)
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- QIAGEN, INC.
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- ROCHE DIAGNOSTICS
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- TABLE 63 ROCHE DIAGNOSTIC TESTS
- SIGMA-ALDRICH, USA
- COMPANY OVERVIEW
- PRODUCTS AND SERVICE
- TABLE 64 MAJOR PRODUCT OFFERINGS OF SIGMA-ALDRICH
- THERMO FISHER LIFE SCIENCES
- COMPANY OVERVIEW
- PRODUCTS AND SERVICES
- TABLE 65 CUSTOMIZED ANTIBODY PRODUCTION PROCESS OF THERMO FISHER LIFE SCIENCES
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