Optimizing Treatment for Bone Metastases in Patients with Advanced Cancers


October 6, 2011
27 Pages - SKU: TAG3804263
License type:
Understand current practice patterns related to bone metastases in patients with advanced cancers. Patient specific unfolding case scenarios presented to 174 high-prescribing oncologists on the treatment of bones metastases in patients with advanced stages of cancer including breast, renal cell carcinoma, and prostate. The survey was presented for their responses on clinical decisions. Oncologists were asked to respond to open-ended questions concerning their choices of treatment regimens, factors that influence their decisions, and barriers to optimal patient management. The survey was administered electronically by Qualtrics survey software between December 15, 2010 and March 31, 2011. Patient progression reveals decisions in treatment throughout patient stages.

Patient case highlights:
  • ER/PR positive HER2/neu negative metastatic breast cancer with bone metastases
  • Metastatic breast cancer with bone metastases in a patient with multiple comorbidities
  • Metastatic clear cell carcinoma with lytic bone lesions
  • Patient with increased PSA and adenocarcinoma
  • Patient with asymptomatic castration-resistant metastatic disease
  • Symptomatic prostate disease in an elderly patient with Gleason’s 5+5 and widespread metastatic disease
Treatment decisions for advanced stages of cancer are difficult to track as information quickly changes along with the introduction of new products that all have an impact oncologists’ choices. This report is part of a series of oncology reports that allow you to see what is actually happening at the patient level for different types of patients presenting with a wide range of issues in advanced stages of cancer.

This report allows you to:

Understand what occurs in physician practice and why
See the variations in practice patterns
Understand where treatments fit in physician decisions
Gain actionable data for marketing strategies


Additional Information

Countries Covered

US

Products Mentioned

Xgeva, Zometa, Sutent, Torisel, Nexavar, Votrient, Avastin, Afinitor, Casodex, Nizoral, Taxotere, Provenge, Prednisone, Aredia, Zytiga
Executive Summary
Introduction
Respondent Demographics
Eligibility Criteria for Survey Participation
Gender of Survey Respondents
Years since Medical School Graduation
Practice Settings
Practices in NCI Cancer Centers
Geographic Settings
Number of Physicians in Practice Groups
Minimal Acceptable Level of Evidence in Determining Treatment Regimen
Treatment of Bone Metasteses in Patients with Advanced Breast Cancers
Patient with ER/PR positive HER2/neu negative metastatic breast cancer
Other than analgesics, treatment of hip pain in a patient with ER/PR positive HER2/neu negative metastatic breast cancer
Treatment of Bone Metastases in Patients with Advanced Breast Cancers
Patient with metastatic breast cancer with multiple comorbidities
Treatment in addition to the aromatase inhibitor for patient’s metastatic breast cancer with multiple comorbidities
Treatment of Bone Metastases in Advanced Renal Cell Cancer
Treatment of good to moderate prognosis renal cell cancer
Initial treatment regimen chosen following surgery
Treatment of Bone Metastases in Advanced Prostate Cancer
Treatment of a patient with increased PSA and adenocarcinoma
Tests to be performed
Treatment of Bone Metastases in Advanced Prostate Cancer
Elderly patient treated for Gleason’s 7 adenocarcinoma, increased PSA 18 months later
Treatment decision upon disease progression
Factors that influenced treatment
Factors that influenced treatment by types of agents selected
Other agents that would be appropriate to include in therapy
Treatment of Bone Metastases in Advanced Prostate Cancer
Elderly patient with Gleason’s 5+5 and multiple metastases
Treatment of patient
Confidence in treating to optimal outcome
Summary
Appendix A: Survey Instrument

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