US Oncologist Survey: Optimizing Treatment for Advanced Renal Cell CancerThe Assessment GroupFebruary 25, 2011 42 Pages - SKU: TAG6197087 |
Additional Information
Report ExcerptIntroduction
Renal cell carcinoma (RCC) is a type of kidney cancer in which the cancerous cells are found in the lining of very small tubes in the kidney. Renal cell carcinoma is the most common type of kidney cancer in adults. It occurs most often in men aged 50 - 70. Sometimes both kidneys are involved. The cancer spreads easily, most often to the lungs and other organs. In about one-third of patients, the cancer has already spread at the time of diagnosis. About half of all cases of RCC are now found by chance when a person gets an imaging test for a different health issue. In these cases, the person might not have any noticeable signs or symptoms of RCC.
A cure is unlikely unless all of the cancer is removed with surgery. Of the people who are diagnosed with RCC, about 25% to 30% already have advanced disease when they are diagnosed. Although patients with early-stage disease can potentially be cured with surgery, many will either experience a recurrence after surgery, or have advanced disease at the time of initial presentation. The outcome depends on how much the cancer has spread and how well it responds to treatment. Possible complications include hypertension, high calcium levels, high red blood cell counts, and liver function abnormalities. Despite significant advances in treatment for advanced renal cell carcinoma, there remains a need to develop new, more effective therapies with improved tolerability.
RCC is generally resistant to standard chemotherapy, and radiation therapy usually does not work, so it is not often used. However, immunotherapeutic regimens have been widely used in patients with advanced disease. Recently, several anti-angiogenesis drugs have demonstrated clinical activity in patients with advanced or metastatic RCC. Although targeted therapies have advanced the treatment of metastatic RCC, complete and durable responses are not achieved in the majority of patients, and a need remains for new treatment options.
- Executive Summary
- Chapter 1: Introduction
- Table 1. Treatment Options in Renal Cell Cancer
- Chapter 2: Respondent Demographics
- Table 2. Eligibility Criteria for Survey Participation
- Figure 2.1 Gender of Survey Respondents
- Figure 2.2 Years since Medical School Graduation
- Figure 2.3 Practice Settings
- Figure 2.4 Practices in NCI Cancer Centers
- Figure 2.5 Geographic Settings
- Figure 2.6 Survey Respondents by State’s Renal Cell Cancer Mortality
- Figure 2.7 Number of Physicians in Practice Groups
- Figure 2.8 Minimal Acceptable Level of Evidence in Determining Treatment Regimen
- Chapter 3: Treatment of Good to Moderate Prognosis Renal Cell Cancer
- Initial treatment regimen chosen following surgery
- Figure 3.1
- Other therapeutic agents that would be considered appropriate to include in therapy
- Figure 3.2
- Treatment decision for medication toxicity
- Figure 3.3
- Second-line therapy treatment
- Figure 3.4
- Factors influencing treatment
- Figure 3.5
- Third-line therapy treatment
- Figure 3.6
- Most important barrier to optimal patient management
- Figure 3.7
- Confidence in managing this patient
- Figure 3.8
- Chapter 4: Treatment of Patient with Poor Prognosis Renal Cell Cancer
- Appropriate treatment regimen
- Figure 4.1
- Treatment regarding metabolic and laboratory abnormalities
- Figure 4.2
- Treatment choice for progressive disease
- Figure 4.3
- Chapter 5: Treatment of Patient with Multiple Comorbidities
- Management of patient with COPD
- Figure 5.1
- Choice of systemic therapy agent
- Figure 5.2
- Tests to monitor to evaluate increased fatigue with pazopanib
- Figure 5.3
- Next systemic treatment choice for progressive disease
- Figure 5.4
- Chapter 6: Treatment of Patient with Comorbidities: Solitary Kidney
- Treatment regimen for patient with solitary kidney
- Figure 6.1
- Treatment for disease progression
- Table 6.2
- Factors influencing treatment decision
- Figure 6.3
- Most important barriers to treatment
- Figure 6.4
- Confidence in managing this patient
- Figure 6.5
- Chapter 7: Summary
- Appendix A: Survey Instrument
More United States Renal reports
Kidney Dialysis Centers by First Research, Inc.
Brief Excerpt from Industry Overview Chapter: Companies in this industry provide outpatient kidney dialysis services. Major companies include US-based DaVita and Dialysis Clinic, Inc., and Germany-based ...
United States Nephrology and Urology Devices Market Outlook to 2018 - Incontinence Devices, Renal Dialysis Equipment and Lithotripters by GlobalData
United States Nephrology and Urology Devices Market Outlook to 2018 - Incontinence Devices, Renal Dialysis Equipment and Lithotripters Summary GlobalData’s new report, “United States Nephrology and Urology ...
North America Nephrology and Urology Devices Market Outlook to 2018 - Incontinence Devices, Renal Dialysis Equipment and Lithotripters by GlobalData
North America Nephrology and Urology Devices Market Outlook to 2018 - Incontinence Devices, Renal Dialysis Equipment and Lithotripters Summary GlobalData’s new report, “North America Nephrology and Urology ...
Kidney Dialysis Centers by First Research, Inc.
See all reports like this >>Brief Excerpt from Industry Overview Chapter: The US commercial kidney dialysis industry includes about 4,200 centers with combined annual revenue of about $18 billion. Major companies ...
More United States reports
D&B Country RiskLine Report: The United States of America by Dun & Bradstreet Inc.
This D&B Country RiskLine Report will help you analyze the risks, opportunities and likely payment delays when doing business in this country. It includes ...
D&B Country Report: The United States of America by Dun & Bradstreet Inc.
D&B Country Report. Comprehensive information for evaluating risks and opportunities when trading or investing in this country. Providing critical information and analysis on ...
Country Report United States January 2011 by Economist Intelligence Unit
Country Reports analyse political and economic trends in featured countries. They show you exactly how national, regional and global events will affect your business in ...
Coal - US - a snapshot (2010) by Mintel - Snapshots
See all reports like this >>Coal in US by Mintel Global Market Navigator provides you with annual year-end market size data, most recently updated in 2010. This market covers consumption ...
Research assistance
We can help you find what you need. Call us or write us: Need help in your search?
US: 800.298.5699
Int'l: +1.240.747.3093
Related Markets
Renal Reports
- End-Stage Kidney Disease (End-Stage Renal Disease or ESRD) – Pipeline Review, H2 2012
- Kidney Cancer (Renal Cell Cancer) Global Clinical Trials Review, H2, 2012
- Kidney Cancer (Renal Cell Cancer) – Pipeline Review, H2 2012
- Acute Renal Failure (ARF) (Acute Kidney Injury) – Pipeline Review, H2 2012
- Renal Cancer Drug Pipeline Update 2012

