Optimizing Lead Selection (3 Volumes)

AdvanceTech Monitor
February 1, 2000
341 Pages - SKU: ATM141175
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Optimizing Lead Selection
  • Executive Summary (pp. 9-16) US $89.00
  • Introduction (pp. 17-19) US $48.00
  • High Throughput Metabolism Screening (pp. 20-44) US $202.00
  • Cytochrome P450 Assays for Miniaturized Formats and Library Screening (pp. 45-57) US $110.00
  • Drug-Drug Interactions: High Throughput Assays to Screen for Inhibition of Human Cytochromes P450 (pp. 58-78) US $181.00
  • Drug Disposition: Rapid Throughput Methods to Quantify Compound Solubility (pp. 79-97) US $157.00
  • Screening Compounds for Oral Absorption Using High Throughput Cellular Assays (pp. 98-105) US $64.00
  • Screening Compounds for CNS Permeability using Blood Brain Barrier Models (pp. 106-130) US $224.00
  • Pharmacogenomics Impact on Early Lead Selection (pp. 131-153) US $193.00
  • In Silico Biology - Virtual Systems and Organs for the Assessment of Drug Candidates (pp. 154-173) US $189.00
  • High-Performance Computing in Pharmaceutical R&D (pp. 174-189) US $123.00
  • Computational Pharmacokinetics for Drug Discovery (pp. 190-200) US $100.00
  • A Consortium Approach to Building a Toxicology Database from Proprietary Compounds (pp. 201-215) US $152.00
  • Use of FDA Databases and Computational Toxicology to Predict Toxicity (pp. 216-230) US $142.00
  • Using State-of-the Art IT Systems to Integrate Preclinical Evaluations into Discovery (pp. 231-254) US $224.00
  • Better Decision-Making Through Data-Mining and Visualization (pp. 255-273) US $155.00
  • Discovery - Solving Developmental Challenges Before They Arise (pp. 274-284) US $108.00
  • Informed Early Attrition (pp. 285-305) US $188.00
  • Cost-Effective Development of Protein Therapeutics (pp. 306-323) US $176.00
  • Creating Value via Better Resource Allocation (pp. 324-343) US $192.00