1. Executive Summary
2. Introduction
3. Negotiating Licensing Agreements for Drug Delivery Technologies
- Deals for enabling/enhancing drug delivery technologies
- Feasibility studies and agreements
- Negotiation of technology licenses
4. Strategic Partnerships at Elan Pharmaceutical Technologies
- EPT's partnering strategy
- Development of feasibility studies
- Development and licensing agreements
- Strategies to extend product life cycles
5. Market Trends in the Drug Delivery Industry
- Drug delivery markets and challenges
- Product life cycle issues
- Drug delivery deal structures
6. Consolidation Trends in the Drug Delivery Industry
- Patent expiration as opportunity for second-generation drugs
- Current pharmaceutical industry issues
- Mergers and acquisitions as drivers for industry consolidation
7. Leveraging a Technology Platform into a Commercial Strategy
- Developing an internal product pipeline
- Collaborations to manage product life cycles
- Collaborations to deliver new chemical entities
8. Targeting a Pharmaceutical Product Pipeline
- Economics, risks and payoffs of new delivery technologies
- Drug delivery alliances Alternate routes, competition, price pressure and vertical integration
9. Capitalizing on New Drug Delivery Technologies
- Drug delivery companies and big pharma: a case of David and Goliath
- Complementary strengths and needs in partnerships
- Do's and don'ts for successful relationships
10. Novel Technologies and Partnering in R&D Portfolio Management
- Strategic use of drug delivery systems
- Deciding on internal vs. external development
- Factors influencing partnership success
11. Drug Delivery Companies — A Wall Street Perspective
- The players behind the consolidation deals
- Increasing value in a fluctuating stock market
12. Pricing, Reimbursement and Regulatory Implications of Novel Systems within Managed Care and Government Programs
- Understanding needs of the target audience for health outcomes evidence
- Regulatory approval challenges posed by new delivery systems
13. Oral Delivery
- Technology Overview
- Increasing gastrointestinal absorptionfor oral delivery of macromolecules
- Benefits of fast-dissolve tablets
- Rapid-dissolve for waterless oral dos-ing; colon-specific drug delivery
- Oral controlled release
- Amorphous and nanocrystalline composites to improve oral solubility
- Aqueous mist delivery of oral insulin
14. Pulmonary Delivery
- Technology Overview
- Benefits and issues of pulmonary delivery of biomolecules
- Dry powder inhalers for systemic drug delivery via the pulmonary route
- Improved inhalation devices for asthma
- Adaptive aerosol delivery systems
- Nasal delivery of pain medications and vaccines
15. Transdermal Delivery
- Technology Overview
- Transdermal and transmucosal drug delivery patches
- Gels, films and microparticles for topical, transmucosal and parenteral use
- Needle-free drug and vaccine delivery by high-velocity, dry powder injection
- Macroflux transdermal technology for local and systemic protein
- Transdermal and transbuccal drug delivery for chronic pain management
- Iontophoresis for inflammation and ophthalmic diseases
16. Liposome-Based Delivery
- Extending circulation time of lipo-somes for protein drug delivery
- Stealth liposomes to target cytotoxic drugs to disease sites
17. Polymers and Microparticles for Drug Delivery
- Polymer-based systems
- Polymer systems for sustained release
- Polymer systems for drug targeting
18. Other Delivery Systems
- Drug delivery applications of the TOGA gene discovery technology
- Formulating water-insoluble drugs to improve delivery
