Pharmaceutical and Biotechnology Construction Sector Report – UK 2012-2016 Analysis


October 1, 2012
95 Pages - SKU: AJLA4886301
License type:
Countries covered: United Kingdom

AMA Research are pleased to announce the publication of the 1st Edition of a new report: “Pharmaceutical and Biotechnology Construction Sector Report – UK 2012-2016 Analysis”. The report should be of particular interest to construction companies and their supply chains operating in the UK Life Sciences sector, and to suppliers of laboratory and allied products.

Key areas in the report:

Introduction to pharmaceutical, medical technology, medical and industrial biotechnology sectors – market size, key players and geographical areas of concentration.

Overview of main manufacturing and R&D facilities in UK.

Analysis of Government resource and capital funding for science and research.

Review of challenges facing the pharmaceutical sector.

Areas of particular interest:

Major contractors, consultants, architects and product suppliers involved in the pharmaceutical and biotechnology sectors.

Capital Expenditure levels in the pharmaceutical market.

Construction costs and issues in the design of pharmaceutical R&D/manufacturing facilities including legislation, regulatory requirements, containment and environmental issues, cleanroom and laboratory design.

Profiles of top pharmaceutical/biotechnology companies operating in the UK - revenue, capital expenditure, key manufacturing & R&D facilities in UK, future strategy, expansion plans, forward pipelines etc.

Government has also announced a forward pipeline of around £250m worth of capital projects in the pharmaceutical sector between 2012- 2017. Review of key projects together with announcements made by leading pharmaceutical companies and universities about future expansion and investment plans.

Detailed analysis of pharmaceutical clusters and centres of excellence in UK - the Oxford, Cambridge and London triangle houses the UK’s largest biomedical cluster, with over 350 pharma and biotech companies linked to universities and other organisations.

Leading pharmaceutical and biotechnology companies mentioned in the report include:

AstraZeneca, Abbott Laboratories, Abcam, ABS Laboratories, ACM Global Central Lab, Aesica Pharmaceuticals, Allergan, Bayer CropScience, Bells Healthcare, Calea (UK), Cancer Research Technology, Cantab Biopharmaceuticals, Carbogen Amcis, Cobra Biomanufacturing, Convergence Pharmaceuticals, Darchem, Eli Lilly, GlaxoSmithKline, Huntingdon Life Sciences, Intercytex, Isis Innovation, Life Technologies, Lonza Biologics, MedImmune, Merck & Co, Mundipharma International, Norbrook Pharmaceuticals, Novartis UK, NuPharm Laboratories, Oxygen Healthcare, Penn Pharma, Pfizer, Pharmaserve Northwest, PsiOxus Therapeutics, Reading Scientific Services, Recipharm, Redx Pharma, Renovo, Roche, Sanofi Aventis, Sareum, Teva Pharmaceutical Industries, TPP Global Development, UCB Pharma, Unilever.

Leading construction companies and consultants mentioned in the report include:

ABB Group, AECOM, AMEC, Ardmac, Bassaire, BDP, Bilfinger Berger, Cavendish Engineers, Clean Air Technologies, Clean Modules, Clean Room Construction, Cleanroom Design & Construction, Cleanroom Solutions, ClearSphere, Enbloc Cleanrooms, Foster Wheeler, Jacobs Engineering, Kier Group, Lend Lease, M+W UK, Mach-Aire, Merit Merrell, Nuvia, Precision Cleanrooms, SDC, Shepherd Construction, Sheppard Robson, Validair, Wilson Mason.

Key areas covered in the report include:

OVERALL ‘ PHARMACEUTICAL’ MARKET

Global Market - analysis of size by value 2008-14, historical trends and market characteristics.

UK Pharmaceutical Market – by value 2011 – overview/ mix of key sectors – Pharmaceutical, Medical Technology, Medical Biotechnology, Industrial Biotechnology.

Review of each key sector – key players, sector value, number of companies/staff, key locations, overview of development pipelines etc.

KEY PLAYERS

Summary overview of Top 30+ companies in Pharmaceuticals / Biotechnology - major companies and geographic location of facilities in UK – Manufacturing, R&D, Packaging, Logistics.

Geographic review – Oxford, Cambridge, London clusters. Other key regional areas - North West, Scotland, East England, South East etc – key players, future trends.

R&D in UK – budgets, funding sources. Government Resource and Capital Funding for Science & Research 2011 – 2015 Research Councils, HEFCE, EPSRC, MRC etc). Key funding recipients. Overview of R&D – key players, locations, development plans.

Top 20 companies in UK by R&D expenditure and by Drug Pipeline 2010/11.

Top players – market shares. Company profiles - Key Operating & Financial Summary Data (Incl: Capital and R&D Expenditure, Locations, Pipelines, Future Strategy etc) -GSK, Astra Zeneca, Novartis, Pfizer, Eli Lilley, Merck, Abbott Laboratories, Roche, Sanofi Aventis, Teva etc.

Review of smaller players – pharmaceuticals / biotechnology – Capex, R&D, locations, developments etc.

Universities – key links/collaborations with private sector, players (Top 20 with funding levels / sources). University/industry collaborations in the Pharmaceutical Sector 2010-11 – Partners, Funding, Project Areas etc.

Spin-out companies - between 2006 and 2010 university spin-out companies floated on the stock market were worth around £3.5bn and over the over the past decade, university bioscience departments alone have generated over 200 spin-out companies – overview of key players.

UK Science Parks - geographical spread, size / development plans, sectors, partners – Biocity, Liverpool, West of Scotland, York, Oxford, Cambridge etc.

CONSTRUCTION ACTIVITY

Capital Expenditure – 2001-2010 by Value – trends, background, drivers etc.

Science & Research Projects - Forward Construction Pipeline 2012-2017 – Schemes, Description, Funding Source, Status, Start/Completion Dates, Capex etc.

Other development announcements – plans – medium/long term, new opportunities etc.

Construction costs – laboratories, cleanrooms, key guidelines.

Leading Contractors – specialist cleanroom players (construction, supply and services).

Key consultants / contractors – Pharmaceuticals, Biotechnology - profiles of 20+ players – sector characteristics, major strengths and weaknesses, key sectors and capabilities.


Additional Information

The UK is the 7th largest pharmaceutical market in the world, and, as such, the sector makes a greater contribution to the UK economy than any other industrial sector – worth around £31.8bn - and generating an annual trade surplus of around £5bn. One fifth of the world’s most popular prescription medicines are currently developed in the UK. The sector is particularly important in terms of its R&D contribution and the pharmaceutical sector alone accounts for more UK-based business R&D than any other manufacturing sector – around £4.6bn was spent on pharmaceutical R&D in the UK in 2010-11, over 28% of total industrial R&D spend.

Industry revenue is forecast to grow by an average of just under 2% between 2012-2016, with growth most noticeable in 2012-13 as the market takes advantage of sales of certain drugs before the effect of the ‘patent cliff’ is seen in 2013 onwards. Growth rates are now significantly slower than in previous years, due to slowing R&D pipelines, dwindling R&D and healthcare budgets, rising costs, impending ‘patent cliffs’, increased regulatory controls and increased pricing pressures. In addition, significant public spending cuts, and tighter NHS spending in particular, is forecast to impact negatively on the pharmaceutical market, with the NHS having less to invest in new drugs.

Much of the industry’s revenue is derived from export sales and the UK is one of the largest exporters of pharmaceuticals by value. The value of UK pharmaceutical exports in 2011 was £20.7bn, an increase of around 4.8%.

The pharmaceutical market is part of the overall Life Sciences sector and includes the medical technology, pharmaceutical, medical and industrial biotechnology sub-sectors and overall generates an annual turnover of £50.6bn and employs around 166,000 people in 4,500 companies. In addition, there are many more companies supplying business support, legal and financial services, marketing and publicity, construction, engineering and design, laboratory products. The pharmaceutical market is relatively mature, with around 67% of companies having operated for around 10 years or more - and around 52% having annual revenues of more than £5m. The top 10 global pharmaceutical companies account for around £19.6bn or 62% of total UK sector turnover.

Many of the top pharmaceutical companies operating in the global market have a considerable manufacturing and research presence in the UK. For example, of the top 50 global pharmaceutical operations, 37 companies have a total of 60 sites in the UK, employing 52,000 staff, representing 83% of total sector turnover.The UK also has many important smaller companies operating in the UK, most of which are in the medical technology and medical biotechnology sectors. Biotechnology companies exist in a number of industrial and medical sectors, including biomedical, food and agriculture, and environmental. The UK leads Europe in the industrial development of biotechnology and during the past decade there has been rapid and sustained growth in the number of specialist biotechnology R&D-based companies.

Capital expenditure by pharmaceutical companies in the UK has been declining since a peak of nearly £1bn in 2001 to its current level of around £500m. The UK is a world-player in researching and producing innovative medicines, but is facing increasing competitive pressure, especially from emerging economies such as India, China and Singapore. For pharmaceutical manufacturing companies, the greatest barrier to capital investment in the UK over the last several years has been the lack of financial incentive to locate new manufacturing (or retain existing manufacturing plants) in the UK. Going forward, the Government has also announced a forward pipeline of around £250m worth of capital projects in the pharmaceutical and biotechnology sectors taking place between now and 2017.
1. INTRODUCTION
2. SUMMARY AND FUTURE PROSPECTS
3. MARKET SIZE AND OVERVIEW
3.1 MARKET DEFINITION, SIZE AND VALUE
3.1.1 Global Pharmaceutical Market
3.1.2 UK Pharmaceutical Market
3.1.3 Medical Technology Sector
3.1.4 Medical Biotechnology Sector
3.1.5 Industrial Biotechnology Sector
3.1.6 Pharmaceutical Sector
3.2 PHARMACEUTICAL/BIOTECHNOLOGY CLUSTERS
3.2.1 Oxfordshire BioCluster
3.2.2 London and Cambridge BioClusters
3.2.3 Geographical Location of Pharmaceutical Manufacturing/R&D
3.3 VALUE OF THE PHARMACEUTICAL INDUSTRY TO THE UK ECONOMY
3.3.1 UK Trade in Pharmaceuticals
3.3.2 Sales of Pharmaceutical Drugs to the NHS
3.4 PHARMACEUTICAL R&D IN THE UK
3.4.1 Government Funding for Science R&D
3.4.2 Pharmaceutical Company Investment in R&D
3.4.3 R&D Pipeline
3.5 MARKET DRIVERS AND KEY ISSUES IN THE PHARMACEUTICAL INDUSTRY
4. LEADING COMPANIES/UNIVERSITIES IN THE PHARMACEUTICAL AND BIOTECHNOLOGY SECTORS
4.1 OVERVIEW
4.2 PHARMACEUTICAL COMPANY LEAGUE TABLES
4.2.1 Global
4.2.2 UK
4.3 COMPANY PROFILES
4.3.1 Abbott Laboratories
4.3.2 AstraZeneca
4.3.3 Eli Lilly
4.3.4 GlaxoSmithKline (GSK)
4.3.5 Merck & Co. Inc
4.3.6 Novartis
4.3.7 Pfizer
4.3.8 Roche
4.3.9 Sanofi-Aventis
4.3.10 Teva
4.4 OTHER PHARMACEUTICAL/BIOTECHNOLOGY COMPANIES
4.4.1 Biotechnology – Therapeutics/Diagnostics
4.4.2 Biotechnology R&D
4.4.3 Pharmaceutical
4.5 COLLABORATION BETWEEN UK PHARMACEUTICALS AND THE ACADEMIC SECTOR
4.5.1 Principal Sources of R&D
4.5.2 Research Funding for Universities
4.5.3 University/Industry Collaborations with the Pharmaceutical Sector
4.5.4 Spin-out Companies
4.5.5 UK Science Parks
5. CONSTRUCTION ACTIVITY IN THE PHARMACHEM AND BIOTECHNOLOGY SECTOR
5.1 CAPITAL EXPENDITURE IN THE PHARMACEUTICAL SECTOR
5.2 PHARMACEUTICAL CONSTRUCTION PROJECT PIPELINE
5.3 CONSTRUCTION ISSUES IN THE PHARMACEUTICAL INDUSTRY
5.3.1 Construction Costs
5.3.2 Contamination/Control Issues
6. CONSTRUCTION CAPABILITY AND SUPPLY IN THE PHARMACEUTICAL & BIOTECHNOLOGY SECTOR
6.1 OVERVIEW
6.1.1 Specialist Cleanroom Construction, Supply and Services
6.1.2 Construction Consultants & Contractors – Pharmaceutical & Biotechnology Sectors
List of Charts and Tables
CHART 1: TURNOVER OF UK PHARMACEUTICAL MARKET (£BN): 2011-2016
CHART 2: GLOBAL PHARMACEUTICAL MARKET AND FORECASTS 2008-2014 BY VALUE (£BN)
TABLE 3: TURNOVER AND NO. OF COMPANIES IN THE UK LIFE SCIENCES SECTOR – BY % AND VALUE (£BN) 2011 – PHARMACEUTICAL, MEDICAL TECHNOLOGY , MEDICAL BIOTECHNOLOGY, INDUSTRIAL BIOTECHNOLOGY
CHART 4: PHARMACEUTICAL & BIOTECHNOLOGY SECTOR – MAJOR COMPANIES AND GEOGRAPHICAL LOCATION OF FACILITIES (UK) – MANUFACTURING, R&D, PACKAGING, LOGISTICS
TABLE 5: DISTRIBUTION OF PHARMACEUTICAL/BIOTECHNOLOGY COMPANIES IN THE GREATER SOUTH EAST REGION (% OF COMPANIES)
CHART 6: PHARMACEUTICAL TRADE IN THE UK 2004-2011 – EXPORTS/IMPORTS BY VALUE (£M)
CHART 7: SALES OF PRESCRIPTION MEDICINES TO THE NHS: 2003 – 2011 (£M)
TABLE 8: GOVERNMENT RESOURCE FUNDING FOR SCIENCE & RESEARCH 2011 – 2015 (£M) – KEY SOURCES (RESEARCH COUNCILS, HEFCE, EPSRC, MRC ETC)
TABLE 9: GOVERNMENT CAPITAL FUNDING FOR SCIENCE & RESEARCH 2011 – 2015 (£M) – BY KEY SOURCES (INCLUDING LARGE FACILITIES CAPITAL FUND)
TABLE 10: TOP 20 PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES BY UK R&D SPEND IN 2010 (£M)*
TABLE 11: TOP 20 PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES BY DRUG PIPELINE SIZE 2011
TABLE 12: MAJOR DRUG PATENT EXPIRATIONS BY PRODUCT AND COMPANY
TABLE 13: TOP GLOBAL PHARMACEUTICAL COMPANIES BY MARKET SHARE (%) 2011
TABLE 14: TOP PHARMACEUTICAL COMPANIES’ UK MARKET SHARE (%) 2011
TABLE 15: ABBOTT LABORATORIES: KEY OPERATING & FINANCIAL SUMMARY DATA (INCL: CAPITAL AND R&D EXPENDITURE, LOCATIONS, PIPELINES, FUTURE STRATEGY ETC)
TABLE 16: ASTRAZENECA: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 17: ELI LILLY: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 18: GLAXOSMITHKLINE: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 19: MERCK & CO.: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 20: NOVARTIS: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 21: PFIZER: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 22: ROCHE: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 23: SANOFI AVENTIS: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 24: TEVA: KEY OPERATING & FINANCIAL SUMMARY DATA
TABLE 25: OTHER TOP PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES: KEY OPERATING & FINANCIAL SUMMARY DATA (CAPITAL AND R&D EXPENDITURE, REVENUES LOCATIONS, ACTIVITIES, TOP DRUGS ETC).
TABLE 26: HEFCE GRANT FOR FINANCIAL YEARS 2008-09 TO 2013-14 (£M)
TABLE 27: HEFCE FUNDING 2012-13 – TOP 20 UK UNIVERSITIES BY SIZE OF GRANT
TABLE 28: UNIVERSITY/INDUSTRY COLLABORATIONS IN THE PHARMACEUTICAL SECTOR 2010-11 – PARTNERS, FUNDING, PROJECT AREAS
TABLE 29: UNIVERSITY SPIN-OUT COMPANIES IN THE PHARMACEUTICAL/BIOTECH SECTOR 2010-11
TABLE 30: UK SCIENCE PARKS – GEOGRAPHICAL SPREAD, SIZE, SECTORS, PARTNERS
CHART 31: UK PHARMACEUTICAL INDUSTRY CAPITAL EXPENDITURE (£M): 2001-2010
TABLE 32: SCIENCE & RESEARCH PROJECTS: FORWARD CONSTRUCTION PIPELINE 2012-2017 – SCHEMES, DESCRIPTION, FUNDING SOURCE, STATUS, START/COMPLETION DATES, CAPEX
TABLE 33: LABORATORY CONSTRUCTION COSTS: 2011 (£M PER SQ. M OF INTERNAL AREA)
TABLE 34: AIRBORNE PARTICULATE CLEANLINESS CLASSES FOR CLEANROOMS (BASED ON ISO 14644-1

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