Pharmaceutical and Biotechnology Construction Sector Report – UK 2012-2016 AnalysisAMA ResearchOctober 1, 2012 95 Pages - SKU: AJLA4886301 |
Additional Information
The UK is the 7th largest pharmaceutical market in the world, and, as such, the sector makes a greater contribution to the UK economy than any other industrial sector – worth around £31.8bn - and generating an annual trade surplus of around £5bn. One fifth of the world’s most popular prescription medicines are currently developed in the UK. The sector is particularly important in terms of its R&D contribution and the pharmaceutical sector alone accounts for more UK-based business R&D than any other manufacturing sector – around £4.6bn was spent on pharmaceutical R&D in the UK in 2010-11, over 28% of total industrial R&D spend.Industry revenue is forecast to grow by an average of just under 2% between 2012-2016, with growth most noticeable in 2012-13 as the market takes advantage of sales of certain drugs before the effect of the ‘patent cliff’ is seen in 2013 onwards. Growth rates are now significantly slower than in previous years, due to slowing R&D pipelines, dwindling R&D and healthcare budgets, rising costs, impending ‘patent cliffs’, increased regulatory controls and increased pricing pressures. In addition, significant public spending cuts, and tighter NHS spending in particular, is forecast to impact negatively on the pharmaceutical market, with the NHS having less to invest in new drugs.
Much of the industry’s revenue is derived from export sales and the UK is one of the largest exporters of pharmaceuticals by value. The value of UK pharmaceutical exports in 2011 was £20.7bn, an increase of around 4.8%.
The pharmaceutical market is part of the overall Life Sciences sector and includes the medical technology, pharmaceutical, medical and industrial biotechnology sub-sectors and overall generates an annual turnover of £50.6bn and employs around 166,000 people in 4,500 companies. In addition, there are many more companies supplying business support, legal and financial services, marketing and publicity, construction, engineering and design, laboratory products. The pharmaceutical market is relatively mature, with around 67% of companies having operated for around 10 years or more - and around 52% having annual revenues of more than £5m. The top 10 global pharmaceutical companies account for around £19.6bn or 62% of total UK sector turnover.
Many of the top pharmaceutical companies operating in the global market have a considerable manufacturing and research presence in the UK. For example, of the top 50 global pharmaceutical operations, 37 companies have a total of 60 sites in the UK, employing 52,000 staff, representing 83% of total sector turnover.The UK also has many important smaller companies operating in the UK, most of which are in the medical technology and medical biotechnology sectors. Biotechnology companies exist in a number of industrial and medical sectors, including biomedical, food and agriculture, and environmental. The UK leads Europe in the industrial development of biotechnology and during the past decade there has been rapid and sustained growth in the number of specialist biotechnology R&D-based companies.
Capital expenditure by pharmaceutical companies in the UK has been declining since a peak of nearly £1bn in 2001 to its current level of around £500m. The UK is a world-player in researching and producing innovative medicines, but is facing increasing competitive pressure, especially from emerging economies such as India, China and Singapore. For pharmaceutical manufacturing companies, the greatest barrier to capital investment in the UK over the last several years has been the lack of financial incentive to locate new manufacturing (or retain existing manufacturing plants) in the UK. Going forward, the Government has also announced a forward pipeline of around £250m worth of capital projects in the pharmaceutical and biotechnology sectors taking place between now and 2017.
- 1. INTRODUCTION
- 2. SUMMARY AND FUTURE PROSPECTS
- 3. MARKET SIZE AND OVERVIEW
- 3.1 MARKET DEFINITION, SIZE AND VALUE
- 3.1.1 Global Pharmaceutical Market
- 3.1.2 UK Pharmaceutical Market
- 3.1.3 Medical Technology Sector
- 3.1.4 Medical Biotechnology Sector
- 3.1.5 Industrial Biotechnology Sector
- 3.1.6 Pharmaceutical Sector
- 3.2 PHARMACEUTICAL/BIOTECHNOLOGY CLUSTERS
- 3.2.1 Oxfordshire BioCluster
- 3.2.2 London and Cambridge BioClusters
- 3.2.3 Geographical Location of Pharmaceutical Manufacturing/R&D
- 3.3 VALUE OF THE PHARMACEUTICAL INDUSTRY TO THE UK ECONOMY
- 3.3.1 UK Trade in Pharmaceuticals
- 3.3.2 Sales of Pharmaceutical Drugs to the NHS
- 3.4 PHARMACEUTICAL R&D IN THE UK
- 3.4.1 Government Funding for Science R&D
- 3.4.2 Pharmaceutical Company Investment in R&D
- 3.4.3 R&D Pipeline
- 3.5 MARKET DRIVERS AND KEY ISSUES IN THE PHARMACEUTICAL INDUSTRY
- 4. LEADING COMPANIES/UNIVERSITIES IN THE PHARMACEUTICAL AND BIOTECHNOLOGY SECTORS
- 4.1 OVERVIEW
- 4.2 PHARMACEUTICAL COMPANY LEAGUE TABLES
- 4.2.1 Global
- 4.2.2 UK
- 4.3 COMPANY PROFILES
- 4.3.1 Abbott Laboratories
- 4.3.2 AstraZeneca
- 4.3.3 Eli Lilly
- 4.3.4 GlaxoSmithKline (GSK)
- 4.3.5 Merck & Co. Inc
- 4.3.6 Novartis
- 4.3.7 Pfizer
- 4.3.8 Roche
- 4.3.9 Sanofi-Aventis
- 4.3.10 Teva
- 4.4 OTHER PHARMACEUTICAL/BIOTECHNOLOGY COMPANIES
- 4.4.1 Biotechnology – Therapeutics/Diagnostics
- 4.4.2 Biotechnology R&D
- 4.4.3 Pharmaceutical
- 4.5 COLLABORATION BETWEEN UK PHARMACEUTICALS AND THE ACADEMIC SECTOR
- 4.5.1 Principal Sources of R&D
- 4.5.2 Research Funding for Universities
- 4.5.3 University/Industry Collaborations with the Pharmaceutical Sector
- 4.5.4 Spin-out Companies
- 4.5.5 UK Science Parks
- 5. CONSTRUCTION ACTIVITY IN THE PHARMACHEM AND BIOTECHNOLOGY SECTOR
- 5.1 CAPITAL EXPENDITURE IN THE PHARMACEUTICAL SECTOR
- 5.2 PHARMACEUTICAL CONSTRUCTION PROJECT PIPELINE
- 5.3 CONSTRUCTION ISSUES IN THE PHARMACEUTICAL INDUSTRY
- 5.3.1 Construction Costs
- 5.3.2 Contamination/Control Issues
- 6. CONSTRUCTION CAPABILITY AND SUPPLY IN THE PHARMACEUTICAL & BIOTECHNOLOGY SECTOR
- 6.1 OVERVIEW
- 6.1.1 Specialist Cleanroom Construction, Supply and Services
- 6.1.2 Construction Consultants & Contractors – Pharmaceutical & Biotechnology Sectors
- List of Charts and Tables
- CHART 1: TURNOVER OF UK PHARMACEUTICAL MARKET (£BN): 2011-2016
- CHART 2: GLOBAL PHARMACEUTICAL MARKET AND FORECASTS 2008-2014 BY VALUE (£BN)
- TABLE 3: TURNOVER AND NO. OF COMPANIES IN THE UK LIFE SCIENCES SECTOR – BY % AND VALUE (£BN) 2011 – PHARMACEUTICAL, MEDICAL TECHNOLOGY , MEDICAL BIOTECHNOLOGY, INDUSTRIAL BIOTECHNOLOGY
- CHART 4: PHARMACEUTICAL & BIOTECHNOLOGY SECTOR – MAJOR COMPANIES AND GEOGRAPHICAL LOCATION OF FACILITIES (UK) – MANUFACTURING, R&D, PACKAGING, LOGISTICS
- TABLE 5: DISTRIBUTION OF PHARMACEUTICAL/BIOTECHNOLOGY COMPANIES IN THE GREATER SOUTH EAST REGION (% OF COMPANIES)
- CHART 6: PHARMACEUTICAL TRADE IN THE UK 2004-2011 – EXPORTS/IMPORTS BY VALUE (£M)
- CHART 7: SALES OF PRESCRIPTION MEDICINES TO THE NHS: 2003 – 2011 (£M)
- TABLE 8: GOVERNMENT RESOURCE FUNDING FOR SCIENCE & RESEARCH 2011 – 2015 (£M) – KEY SOURCES (RESEARCH COUNCILS, HEFCE, EPSRC, MRC ETC)
- TABLE 9: GOVERNMENT CAPITAL FUNDING FOR SCIENCE & RESEARCH 2011 – 2015 (£M) – BY KEY SOURCES (INCLUDING LARGE FACILITIES CAPITAL FUND)
- TABLE 10: TOP 20 PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES BY UK R&D SPEND IN 2010 (£M)*
- TABLE 11: TOP 20 PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES BY DRUG PIPELINE SIZE 2011
- TABLE 12: MAJOR DRUG PATENT EXPIRATIONS BY PRODUCT AND COMPANY
- TABLE 13: TOP GLOBAL PHARMACEUTICAL COMPANIES BY MARKET SHARE (%) 2011
- TABLE 14: TOP PHARMACEUTICAL COMPANIES’ UK MARKET SHARE (%) 2011
- TABLE 15: ABBOTT LABORATORIES: KEY OPERATING & FINANCIAL SUMMARY DATA (INCL: CAPITAL AND R&D EXPENDITURE, LOCATIONS, PIPELINES, FUTURE STRATEGY ETC)
- TABLE 16: ASTRAZENECA: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 17: ELI LILLY: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 18: GLAXOSMITHKLINE: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 19: MERCK & CO.: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 20: NOVARTIS: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 21: PFIZER: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 22: ROCHE: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 23: SANOFI AVENTIS: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 24: TEVA: KEY OPERATING & FINANCIAL SUMMARY DATA
- TABLE 25: OTHER TOP PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES: KEY OPERATING & FINANCIAL SUMMARY DATA (CAPITAL AND R&D EXPENDITURE, REVENUES LOCATIONS, ACTIVITIES, TOP DRUGS ETC).
- TABLE 26: HEFCE GRANT FOR FINANCIAL YEARS 2008-09 TO 2013-14 (£M)
- TABLE 27: HEFCE FUNDING 2012-13 – TOP 20 UK UNIVERSITIES BY SIZE OF GRANT
- TABLE 28: UNIVERSITY/INDUSTRY COLLABORATIONS IN THE PHARMACEUTICAL SECTOR 2010-11 – PARTNERS, FUNDING, PROJECT AREAS
- TABLE 29: UNIVERSITY SPIN-OUT COMPANIES IN THE PHARMACEUTICAL/BIOTECH SECTOR 2010-11
- TABLE 30: UK SCIENCE PARKS – GEOGRAPHICAL SPREAD, SIZE, SECTORS, PARTNERS
- CHART 31: UK PHARMACEUTICAL INDUSTRY CAPITAL EXPENDITURE (£M): 2001-2010
- TABLE 32: SCIENCE & RESEARCH PROJECTS: FORWARD CONSTRUCTION PIPELINE 2012-2017 – SCHEMES, DESCRIPTION, FUNDING SOURCE, STATUS, START/COMPLETION DATES, CAPEX
- TABLE 33: LABORATORY CONSTRUCTION COSTS: 2011 (£M PER SQ. M OF INTERNAL AREA)
- TABLE 34: AIRBORNE PARTICULATE CLEANLINESS CLASSES FOR CLEANROOMS (BASED ON ISO 14644-1
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